Diabetic Cat Sniffing Everything, Not Recognising Anyone

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Sarah Fitzsimmons

Member Since 2021
Hi,

My name is Sarah, I am new to this page and hope someone can help me. I am a cat mummy to 3 little fur babies and one has recently been very ill. They mean the world to me and my partner so any help would be very much appreciated.

A bit of background on my cat (boy, ginger aged 12), was diagnosed with diabetes around 6 weeks ago. After several tests his caninsulin was increased to 4 units twice a day at 8am and 8pm, he eats cooked 100g of chicken and fish twice a day around the time he has his caninsulin (which he was also eating months before he was diagnosed with diabetes). Since the diagnosis one of his eyes blinks on its own and quite often, he's up and down throughout the day and around the time he is due his caninsulin he looks ill/uncomfortable.

Today we came home after being out for a few hours (around 2pm which is the lowest point of his curve) to find him sniffing everything and not responding to us when we called him or tried to get his attention. He looked like he was unable to see and that's why he was sniffing everything and moving around quite erratically like he was lost or confused. We shined a light in his eyes to see if they were responding but couldn't see properly as he was frantically moving and wanting to sniff everything.

We took him to the vets straight away and informed them that we had read simular stories on here and think that he had gone hypo, they took him straight through to check his blood. After some time they called us in, they checked his eyes which responded slightly to light, the vet put him on the floor and he crawled low slowly into a corner sniffing, the vet was sure he was blind. His blood glucose level was 7.6, they did an organ function blood test and basic bloods, the only thing that came back high were his platelets and his red blood cell size were small, mcv?
His blood was checked again 15-20mins later and had gone up to 8.2. The vet suggested it could be a tumour, cyst from paracites, diabetic neuropathy and suggested we get a referral for MRI (£3-5k). Felt a bit like they had written him off!
As we were about to leave around an hour after arriving he seemed to be more responsive, he saw something in the table, my hand and knew where the table was as he jumped out of my arms onto it. He was rubbing his head up against us like he normally does and had a happy hook tail.

Around 5 hours after we got home we called the vets to see how he is, as soon as I gave his name the vets assistant she said "Oh I know him, he's being very cuddly!" He had eaten all his food and was enjoying lots of cuddles and attention (he loves the ladies and is a very affectionate and cuddly cat), when we questioned his eye sight she said he can see her hand moving but couldn't confirm anything as she was the assistant and not the vet.

I am unsure if he was blind/temporary blind or was it some kind of "malfunction".
We are hesitant to go do the path of an MRI straight away because we have read on here that it is a known occurrence for this to happen to diabetic cats on caninsulin.
We are looking into checking his blood ourself but not sure how that works e.g how to adjust his units etc.

Any help, suggests, advice, tips - anything, would be welcome.
Thank you in advance x
 
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I think it's very possible that your cat had a severe hypo episode which can quite often cause blindness. It's usually temporary but not always.

4U is a huge dose of insulin and if he's only been diagnosed for 6 weeks, he shouldn't be anywhere near that high of a dose! We recommend starting at .5 and increases should be in .25 to .5 unit increments (so at 6 weeks, the most he should be getting is 1.5-2U.

Are you home testing? Tests done at the vet's are unreliable due to vet stress which can raise the blood glucose by up to 11 points.

Where do you live? Since you're calling it Caninsulin, you have to be somewhere other than the US. Caninsulin is also not a very good insulin for cats. The prefix "canin" makes it pretty clear it's a better dog insulin.

What are you currently feeding? He should be eating a low carb canned food (we can help with suggestions when we know where you are).

I'm happy to hear he seems to be recovering, but please let us help you so you don't risk something like this again!
 
I think it's very possible that your cat had a severe hypo episode which can quite often cause blindness. It's usually temporary but not always.

4U is a huge dose of insulin and if he's only been diagnosed for 6 weeks, he shouldn't be anywhere near that high of a dose! We recommend starting at .5 and increases should be in .25 to .5 unit increments (so at 6 weeks, the most he should be getting is 1.5-2U.

Are you home testing? Tests done at the vet's are unreliable due to vet stress which can raise the blood glucose by up to 11 points.

Where do you live? Since you're calling it Caninsulin, you have to be somewhere other than the US. Caninsulin is also not a very good insulin for cats. The prefix "canin" makes it pretty clear it's a better dog insulin.

What are you currently feeding? He should be eating a low carb canned food (we can help with suggestions when we know where you are).

I'm happy to hear he seems to be recovering, but please let us help you so you don't risk something like this again!

Hi, thank you so much for your reply.
Firstly, I have made an error on my thread, he is on 0.4 units not 4 units - still at the top end but not out of the range, he started on 0.3 units but after his first few weeks it didn't seem to be reducing his blood glucose levels so they increased it to 0.4 units.

No we are not testing but is something we want to do, we don't understand enough about it yet so any help on that too would be grateful.

Yes we are in the UK, East London. Caninsulin is what they seem to use over here, not sure if we have any other options.

He has been eating cooked chicken and fish (100g twice a day), which I cook every 1-2 days as the vets said he can only eat around 15 mins before his injection. He usually bothers us a couple of hours before he is due to eat, he's used to grazing on food throughout the day or having the odd snack/treat which have completely stopped now.
We used to feed them all canned food and dry food but he also suffers from crystals in his urine and his sister used to get blood in her poop which the vets thought could be a food intolerance, she used to be very bloated too, since changing to the cooked food she has got so much better, less pooping from all overall. Again, something we are still fairly new too so any tips there would be great.

Any help would be appreciated, as I said he means the world to us and want to do what we can to help him - he's a strong boy so we're not giving up on him yet!
Thanks in advance.
Sarah x
 
You mean he is on less than half a unit of caninsulin twice a day? That’s fairly low - what is his weight? Can you get a libre fitted? That will give you idea of glucose over 2 weeks - or of you can test using glucometer (blood from ear).
I think it sounds like he was very disoriented- possibly hypo, if he is overweight at all look at RCVS clinical trial for diabetic cats.
Mine has showed change in smell sometimes since starting treatment - like very alert to smelling things but his eyesight seems fine.
On balance, without further test, I would say he was hypo . One thing may be to simply take him to a different vet for second opinion?
If not overweight I think you can a small snack in between meals just not so much he won’t eat at injection time
 
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Hi, thank you so much for your reply.
Firstly, I have made an error on my thread, he is on 0.4 units not 4 units - still at the top end but not out of the range, he started on 0.3 units but after his first few weeks it didn't seem to be reducing his blood glucose levels so they increased it to 0.4 units.

No we are not testing but is something we want to do, we don't understand enough about it yet so any help on that too would be grateful.

Yes we are in the UK, East London. Caninsulin is what they seem to use over here, not sure if we have any other options.

He has been eating cooked chicken and fish (100g twice a day), which I cook every 1-2 days as the vets said he can only eat around 15 mins before his injection. He usually bothers us a couple of hours before he is due to eat, he's used to grazing on food throughout the day or having the odd snack/treat which have completely stopped now.
We used to feed them all canned food and dry food but he also suffers from crystals in his urine and his sister used to get blood in her poop which the vets thought could be a food intolerance, she used to be very bloated too, since changing to the cooked food she has got so much better, less pooping from all overall. Again, something we are still fairly new too so any tips there would be great.

Any help would be appreciated, as I said he means the world to us and want to do what we can to help him - he's a strong boy so we're not giving up on him yet!
Thanks in advance.
Sarah x
I don't understand this dose. 0.4 would be just a few drops, below the first line in the siringe. You are filling it below the first little line in the syringe? Or are you filling it to the 4th line on the syringe? Because that's a very large dose. Can you post a picture of where you are filling your syringe to?
 
Maybe you can check the prescription label on the insulin box - I presume you are using a U-40 syringe and drawing from the vial?
 
I agree with Janet ……can you post a photo of the syringe you use and where you draw this insulin up to?
You will need to copy and paste the photo as our upload a file is not working atm.
 
Also Sarah - am thinking you maybe give a quick call to your vet just to double check all this out / dosing etc given that they are likely to close soon for the weekend. Have yet to see a vet that doesn’t close around lunchtime on Saturday in UK
 
You mean he is on less than half a unit of caninsulin twice a day? That’s fairly low - what is his weight? Can you get a libre fitted? That will give you idea of glucose over 2 weeks - or of you can test using glucometer (blood from ear).
I think it sounds like he was very disoriented- possibly hypo, if he is overweight at all look at RCVS clinical trial for diabetic cats.
Mine has showed change in smell sometimes since starting treatment - like very alert to smelling things but his eyesight seems fine.
On balance, without further test, I would say he was hypo . One thing may be to simply take him to a different vet for second opinion?
If not overweight I think you can a small snack in between meals just not so much he won’t eat at injection time

It's 4 international units? Sorry for the confusion, as you can see this is all new to me!
What's a libre? He had a Fructosamine test a month ago to test his bloods for the previous 2 weeks and it was all fine. I'll look into a glucometer, thanks.
He weighed 5.8 kilos yesterday, he lost a lot of weight before he was diagnosed so he has put his weight back on.
Thanks for your help, will see what the update is from the vets today.
Sarah
 
I don't understand this dose. 0.4 would be just a few drops, below the first line in the siringe. You are filling it below the first little line in the syringe? Or are you filling it to the 4th line on the syringe? Because that's a very large dose. Can you post a picture of where you are filling your syringe to?
He has 4 international units, sorry I think I've confused it. Its 4 units so quite a lot.
 
He’s on 4 units twice a day??????
So 8 units total in a day??
Using a U-40 syringe (not a U-100)?
Ok, he’s not overweight.
Freestyle libre - a glucose monitor they fix to skin , can give up to 2 weeks reading by scanning using phone.
BUT 4 units is ALOT
 
Maybe you can check the prescription label on the insulin box - I presume you are using a U-40 syringe and drawing from the vial?

Sorry tried to upload a photo but it won't let me!
Yes we are using the U-40 syringes and the 4th line down (4 untis)
 
Mine had/has very high readings and is very big and he has 4 units in total a day, so can just about take it.
 
Ok - so next question :
Does syringe have 0.5 markings or 1 unit markings?
Are you giving 4 once or twice a day?
 
Also Sarah - am thinking you maybe give a quick call to your vet just to double check all this out / dosing etc given that they are likely to close soon for the weekend. Have yet to see a vet that doesn’t close around lunchtime on Saturday in UK
Our vet is 24/7 so they are open. They are good at keeping us informed just want to make sure we are being informed the right information!
 
He’s on 4 units twice a day??????
So 8 units total in a day??
Using a U-40 syringe (not a U-100)?
Ok, he’s not overweight.
Freestyle libre - a glucose monitor they fix to skin , can give up to 2 weeks reading by scanning using phone.
BUT 4 units is ALOT
I know but his blood sugar was through the roof, at the beginning it was as high as 28.6 and wasn't reducing like they wanted which is why the increased it to 4 units.
OK I will look into that, thank you
 
Ok - so next question :
Does syringe have 0.5 markings or 1 unit markings?
Are you giving 4 once or twice a day?
It has 0.5 markings on the left and 1 unit markings on the right, he has the 4th line down on the right, so 4 units. Yes he has 4 units twice a day.
 
I really feel like that dose is too much. Here's what I would do if it were my cat. I'd cut that dose in half until I learned to test with a blood meter. If through testing it showed it wasn't enough, raise the dose in small 0.25-0.5 increments. Any meter is fine to use, but look for one that only needs a 0.3-0.5 size sample.

Get
1. A meter
2 100 extra test strips
3 26-28 gauge lancets
4 Cotton rounds to go behind the ear and protect your fingers.

I have a video in my signature showing how I tested my cat CC at home. I know it is intimidating but once you get the hang of it is pretty easy. We are here for you.
 
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Ok - 8 units total a day is a lot. I don’t know what your fructosamine was. My first was 770, and his blood panel glucose 28. I started on 1.5 units twice a day, after that fructsamine came down to 550, I’m now on 2 units twice a day.
It may be mine needs to go higher but have also changed diet but if going higher I would only do it with close monitoring. -
I suggest: either reduce dose (with vet guidance) or get home glucose monitor to do readings throughout day or get a libre fitted . Just my opinion obviously
 
It has 0.5 markings on the left and 1 unit markings on the right, he has the 4th line down on the right, so 4 units. Yes he has 4 units twice a day.

Ok - that is a lot - it’s too much IMO. I wonder if he’s having somigyi effect (too much insulin- gets too low body compensates and effect is high glucose readings )…
I think sometimes vets can look at high readings and go in aggressively to bring down, but it needs to be done slowly and also take into account food eaten /type. Mine is still on relatively high carbs . Yours is not .
 
No we are not testing but is something we want to do, we don't understand enough about it yet so any help on that too would be grateful.
Hi Sarah, waving to you from Surrey!

I agree with the comments above that this does sound very much like hypo... And I also agree that the insulin dose should be reduced.
4 units is a very high dose for a recently diagnosed cat...

If you can learn to hometest blood glucose that will make the diabetes easier to manage and also safer for your kitty.
'Most' people who try to test can learn to do it, and 'most' cats can be tested (of course there are a few exceptions). The test is a really quick process, and should not hurt the cat. If they are rewarded with treats or a little grooming session they can even come to enjoy the process!

The most popular glucose meter among UK'ers at the moment is the Gluco Navii. It's also one of the cheapest to use. It's a human glucose meter, but human meters work just fine for cats.

Caninsulin is what they seem to use over here, not sure if we have any other options.
There is a long history of prescribing Caninsulin for cats in the UK, but in fact it is no longer a 'recommended' insulin in the current international guidelines. It can act quite fast in the system and 'typically' doesn't last a full 12 hours; 8 - 10 hours is more likely. The international guidelines (and also the RVC) recommend longer lasting insulins for cats. And in the UK Prozinc is the only long lasting insulin that is actually licensed for cats. Vets are gradually switching over to Prozinc but it is a slow process...

That said, some cats do just fine on Caninsulin. But, if it doesn't work well for your cat then you do have the option of getting your vet to prescribe Prozinc.
Prozinc costs more than Caninsulin. But both Caninsulin and Prozinc can be bought more cheaply from an online pharmacy with a prescription from your vet.

I know but his blood sugar was through the roof, at the beginning it was as high as 28.6 and wasn't reducing like they wanted which is why the increased it to 4 units.
OK I will look into that, thank you
Sarah, how did they determine that the dose increase was warranted?
Was there a blood glucose curve at the vet? Spot check blood glucose test? Fructosamine test..?

BTW, there is lots of info for new UK members in my signature below this post. :bighug:

Eliz
 
...the vets said he can only eat around 15 mins before his injection. He usually bothers us a couple of hours before he is due to eat, he's used to grazing on food throughout the day or having the odd snack/treat which have completely stopped now.
This advice is very 'old school', and the current thinking is that diabetic cats can benefit from being fed more than twice a day. The international guidelines and the RVC's own guide say that if a cat is used to be being fed more frequently, or if they are a 'grazer', then they can continue to do this (as long as the calories remain appropriate for their needs).
Also, Caninsulin can sometimes drop the blood glucose quite quickly. To counteract this some people feed a snack or mini-meal about an hour or so after the insulin shot. This can sometimes help to slow down any fast drop in blood glucose.

Eliz
 
Agree with the above, in fact I have just given my pudding a small snackie . I gave 2 units insulin at 7.45am this morning and I felt he was looking a bit low/unsettled, and he ate it all with gusto. He’s snoozing now but I feel happier knowing there is a little something to tide him over until his 745pm dinner and injection tonight. This is not on advice of vet - who told me same thing - feed twice a day only, but based on my own observations and common sense tbh. I still give his 2 main meals twice a day but if I need to give maybe one 5th (5g in his case) a little earlier I do. And give the rest at his meal time.
 
But I get that it is a total learning curve… for me also, been at this since May, am knackered already!
 
It can be a steep learning curve but everyday gets easier.
If hearing this from one more person means anything; Caninsulin is hard on the system and almost never lasts an entire cycle. We free fed both our diabetic cats, they were never meant to eat two meals a day. Using a meter will give a much better understanding of what's going on with your cat, giving insulin without one is like driving with your eyes closed.
Our Jasper had an MRI and a spinal tap and my neurological story is too long to tell. Sometimes a medical event has no explanation, it happens once and that's it. Ten years later and doctors still want to poke around inside my brain, no thanks. I'm not saying you shouldn't pursue an answer as to what happened but some doctors forget it's a living being they're dealing with and not a lab experiment.
 
Are you able to take a photo and copy and paste it Sarah so we can see pleases.?
Did you start off with a small dose and work your way up? If so how did you do it? In 1 unit increments?
This advice is very 'old school', and the current thinking is that diabetic cats can benefit from being fed more than twice a day. The international guidelines and the RVC's own guide say that if a cat is used to be being fed more frequently, or if they are a 'grazer', then they can continue to do this (as long as the calories remain appropriate for their needs).
Also, Caninsulin can sometimes drop the blood glucose quite quickly. To counteract this some people feed a snack or mini-meal about an hour or so after the insulin shot. This can sometimes help to slow down any fast drop in blood glucose.

Eliz
Thank you so much for your info, it's really useful.
We just called the vets for an update and to see if he will be coming home today and the receptionist said the vet was busy but would make an appointment at 5pm today for us to go up there to talk to them but he won't be coming home today. Which is a bit co corning as we have never had to go in for a "chat" before without taking him home so obviously we are now thinking the worst.
 
If it were something bad they would have you in much sooner.
The only good thing about 5PM is you'll have time to make up a list of questions. It's been my experience that by 5PM on a Saturday people are tired and want to go home, I once caught a doctor glancing at her watch as if I were annoying her. Ask to come in sooner, politely demand it if you have to. The staff at emergency clinics may have knowledge but they often lack the compassion your own vet does.
 
Please let us know what the vet said.

The first thing I thought of asking was are you adding taurine to the cooked chicken and fish? If not, a lack of taurine can cause retinal degeneration and cause blindness. From https://www.vin.com/apputil/content/defaultadv1.aspx?id=3862868&pid=11254
Feline central retinal degeneration (FCRD) is caused by a nutritional deficiency of taurine, a disorder unique to cats. At present, all US commercial cat foods contain an adequate concentration of taurine for the vast majority of cats, making this disease rare among cats that are fed a proper diet. It is still sporadically seen in cats that are fed either homemade diets or dog food. In addition, it is occasionally seen in cats on an appropriate diet, suggesting that the requirement for taurine may be even higher for selected cats.

Taurine deficiency affects first the cone photoreceptors most prominent in the area centralis dorsotemporal to the optic disc. Deficiency results in bilaterally symmetrical elliptical areas of hyperreflectivity that appear first in the area centralis. As the disease progresses, similar lesions appear dorsomedial to the optic disc. Gradually, the two lesions converge creating a hyperreflective band dorsal to the optic nerve. If left untreated, slow progression throughout the entire retina may result in blindness. Correction of the taurine deficiency will stop progression of the disease, but will not result in correction of lesions that are already there. Affected cats should be monitored for cardiomyopathy.
 
We just called the vets for an update and to see if he will be coming home today and the receptionist said the vet was busy but would make an appointment at 5pm today for us to go up there to talk to them but he won't be coming home today. Which is a bit co corning as we have never had to go in for a "chat" before without taking him home so obviously we are now thinking the worst.
The vet may just be being cautious. Don't lose heart... :bighug::bighug::bighug:
And do update us when you can. (((Hugs)))

Eliz
 
The vet may just be being cautious. Don't lose heart... :bighug::bighug::bighug:
And do update us when you can. (((Hugs)))

Eliz
Thank you all for your help and lovely messages.

Here is a photo of the syringes we are using and the mark you are at.

So to update you, we went to the vets at 5pm, anxious as hell! When we checked in the receptionist said "I'll find you a room", again panic kicked in because we've never "had a room".
The nurse brings him into the room so we can see him and he is on a drip of fluids, waiting for the vet to come and talk to us, we are again anxious wondering what the hell is going on. We gave him all the love we could as he seemed like his normal self and sight back to normal, only thing we noticed was his nose and inside ears looked a little darker, almost like they ate bruised, especially his nose.

So the Vet comes out and is unsure what has happened and he seems OK now so we can take him home (!!!)
They suggested he could have had a stroke, a blood clot but agreed the possibility of a hypo is there (after we mentioned the info we got from this group). He agreed the dosage is quite high and suggested we decrease to 2 units tonight. Which to be honest we thought would be a dramatic change so we opted to 3 units tonight at 8pm and see how he goes. He seems OK except he is now (11.15pm) walking around and licking the empty bowls, like he is hungry.

I have ordered the glucose testing kit you suggested Elizabeth from amazon so hopefully should arrive tomorrow. The vet also suggested we test his blood regularly to monitor him ourselves.
He seems like himself again but we are both on edge and noticing every little thing now!

Something else strange that just happened, he was asleep in his bed next to me and I noticed the end of his nose had blood on it, randomly out of the blue a small dot, I'll try and upload a photo of it. It seems to have dried now so not loads of blood just a small dot/scab.

As I finish typing this he's now on my lap having a good purr and falling asleep just like he normally does so I'm even more baffled than I was 24 hours ago!!

Thank you all again for you help and support, I'll keep you updated!
Sarah x

nXPpkMD
YhNCXB5
 
I can’t see the images.
I am glad he has improved and is home.
After a symptomatic hypo ( if that is what he had) a lot of cats can be very sensitive to the insulin.
I would have followed the vets advice and reduced to 2 units until you are testing and can see what is happening. If he is looking for food, please feed him as hunger can be a sign of low numbers.
I would also get some Ketostix from a pharmacy or Walmart to test the urine for ketones which can be a concern if the dose is dropped if the cat is prone to ketones.
 
Someone will correct me if this is wrong. You can lay a sheet of clear plastic food wrap over the litter and get a pee sample that way.
Much easier than me chasing a 60 lb. dog with an aluminum pie plate. :eek: o_O
 
Thank you all for your help and lovely messages.

Here is a photo of the syringes we are using and the mark you are at.

So to update you, we went to the vets at 5pm, anxious as hell! When we checked in the receptionist said "I'll find you a room", again panic kicked in because we've never "had a room".
The nurse brings him into the room so we can see him and he is on a drip of fluids, waiting for the vet to come and talk to us, we are again anxious wondering what the hell is going on. We gave him all the love we could as he seemed like his normal self and sight back to normal, only thing we noticed was his nose and inside ears looked a little darker, almost like they ate bruised, especially his nose.

So the Vet comes out and is unsure what has happened and he seems OK now so we can take him home (!!!)
They suggested he could have had a stroke, a blood clot but agreed the possibility of a hypo is there (after we mentioned the info we got from this group). He agreed the dosage is quite high and suggested we decrease to 2 units tonight. Which to be honest we thought would be a dramatic change so we opted to 3 units tonight at 8pm and see how he goes. He seems OK except he is now (11.15pm) walking around and licking the empty bowls, like he is hungry.

I have ordered the glucose testing kit you suggested Elizabeth from amazon so hopefully should arrive tomorrow. The vet also suggested we test his blood regularly to monitor him ourselves.
He seems like himself again but we are both on edge and noticing every little thing now!

Something else strange that just happened, he was asleep in his bed next to me and I noticed the end of his nose had blood on it, randomly out of the blue a small dot, I'll try and upload a photo of it. It seems to have dried now so not loads of blood just a small dot/scab.

As I finish typing this he's now on my lap having a good purr and falling asleep just like he normally does so I'm even more baffled than I was 24 hours ago!!

Thank you all again for you help and support, I'll keep you updated!
Sarah x

nXPpkMD
YhNCXB5
I'm glad he's don't better.... If he's licking the bowls he's hungry please feed him!!!!! He may be doing so to get his numbers up. Absolutly lower to 2 units. After a hypo they can be very sensitive. I remember once bringing my cat to the er for a hypo. The next shot I did I gave 1/3 what I would have normally given and she hypoed again and we were back in the er.

Please provide food in between meals. They can eat any time except for 2 hours prior to the preshot test. I have a video in my signature showing how I tested my cat CC at home.
 
Hi,
@Sarah Fitzsimmons

An excellent point is risen in reply #31.
Do you add taurine(and other supplements) to your homemade food?
My cat lost her vision after sever Hypo episode but recovered most of it.
During that time she 'd rely on sniffing more than normal.
Here is the link to the ready to use premix for homemade cat food in case you haven't come across it yet.
Wishing your kitty the very best.
 
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