12/5 Oberon +8 299, AMPS 431, +2.5 441, +4 409, +7 408, +10 414, PMPS 420, +3 389, +5 386

I'm sure Oberon is going to be back to work soon enough.:cat:
Holy cow! I've given presentations where things went wrong and I had to wing it or smile through the disaster (in my job talk for my current job, my final summary graphic was a big red X thanks to a Mac-PC incompatibility)
Yikes! :eek: I feel like I have stuff go wrong a lot, much of it of my own doing.:rolleyes: Getting an embedded video to play during a presentation and then making sure that everyone on the Teams/Zoom call can hear it is something I am incapable of. So embarrassing.:facepalm: Dealing with the seizure was way easier.

Have a great day:bighug:
 
I've been wondering why, if the antibodies are fading, we're still getting all these high numbers. I would have hoped that as the antibodies declined his "baseline" (when antibodies are binding insulin) would also decrease, because there would be more free insulin to bring BG down. Not seeing any sign of that yet, unless that's part of what's going on today.
Have you ever looked at Neko's SS when her antibodies were breaking? Mid August on in 2012. There was also the combo of SRT happening. We used to use lime green for all greens on the SS, so that part looks different, but overall not too dissimilar patterns. Other than the fact she was guaranteed to bounce so I didn't have to BCS or skip, though I did occasionally do back to back reductions. I felt like I was pushing hard against a tide of antibodies, occasionally I could get through, then it would wash back again. Sort of like some antibodies would die and release insulin, then a fresh batch would start up, but not as many.
 
Wow, that's impressive. I also see on his SS that he ended up going back up to around 5 U later, then eventually back down and OTJ. What led to the increase?.
What led to the increase? I’ll start with what led to the initial decrease. BK had developed a lump, a little larger than a marble, just above the scruff. It was removed on 10/23/2008 and thankfully was benign. while he was under anesthesia for the surgery the vet took the opportunity to take a good look at his teeth and gums. There was a tooth way in the back of his mouth that had broken away but not completely- there was a part of the root still there which she easily removed. His teeth and gums were beyond what she was comfortable handling and she referred me to a veterinary dental specialist.

You can see on the ss tremoval of the lump and tooth fragment was a tuning point-and I started laying off the R. He had a major dental surgery with the specialist on 12/08/2008; something like 8 extractions, and we were sent home with 7 days of antibiotics. Once the antibiotics were finished on 12/ 14/2008 the slide down the dosing ladder started picking up steam. He had his first taste of HC on 01/04/2009, nearly a year from the time he started insulin therapy.

BK was the last kitty anyone, including myself expected would go OTJ, so it was very exciting around in Lantus Land during his rapid descent down the dosing ladder. All signs were pointing in that direction. Folks were joking about BK having turned into a microdose kitty - spirits were high.

Then pink stared coming back into the picture, and then red...and his dose crept back up to 5.25. I was completely devastated. One day in May of 2009 BK yawned one of those big yawns and I happened to see some redness in his upper lingual gums far in the back. On 5/29/2009 it was back to the dental specialist where he had another 3 or 4 extractions.
He saw his last pink on 6/3/2009 and the slide down resumed, this time all the way to zero.
 
Wow! OK, that makes me think yet again that I need to have his teeth checked more closely. Vets keep telling me they don't look bad, but I'm not convinced they're really doing a thorough check. The ER hospital he's been to also has a dental department, so maybe I should talk to them at some point. Right now I kind of don't want to mess with anything while he's clearly sliding down the dosing ladder, though.
 
Wow! OK, that makes me think yet again that I need to have his teeth checked more closely. Vets keep telling me they don't look bad, but I'm not convinced they're really doing a thorough check. The ER hospital he's been to also has a dental department, so maybe I should talk to them at some point. Right now I kind of don't want to mess with anything while he's clearly sliding down the dosing ladder, though.
BKs teeth and gums were clearly his Achilles heel. If Oberon has never had a dental cleaning, consider getting him to a specialist. Keep in mind that kitties don’t “open up and say ahhh” and even if they did you don’t know what is going on under the gum line. There could be resorptive lesions that are only visible if radiographs are taken.

Infection and inflammation not only raise BG they are a key ingredient in the formation of ketones which put a kitty at risk of DKA.
 
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