11/5 Oberon AMPS 284, +2 334, +4 367, +6 338, +8 347, +10 335, PMPS 359, +2 357, +3.75 433

One thing is for sure....Oberon is an exciting cat :)....whether it be by choice with his escapes or his little body doing it’s own thing :nailbiting:. Best with the new dosing :bighug:
 
Hmm. I was tentatively planning to give midcycle R to help with the bounce, but he's actually dropped a little on his own at +6. Not sure what to make of it, but I suspect I should hold off.
 
Lisa & Oberon said:
Hmm. I was tentatively planning to give midcycle R to help with the bounce, but he's actually dropped a little on his own at +6. Not sure what to make of it, but I suspect I should hold off.
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I would do the same.
When an IAA kitty suddenly goes green-heads up. Always err on the side of caution. There is no way to know how much previously bound up insulin has been released back into circulation and how long the effects may last.

Good instincts :cool:
 
Sandy and Black Kitty said:
I would do the same.
When an IAA kitty suddenly goes green-heads up. Always err on the side of caution. There is no way to know how much previously bound up insulin has been released back into circulation and how long the effects may last.

Good instincts :cool:
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Good to know I'm on the right track! I figure he's had IAA for at least 4 months now, possibly longer, and I know it usually lasts months to a year or so. I think it's possible it got triggered when he was on Lantus for about 2 weeks last December, in which case it's been building for more like 11 months. So he might be close to done, or I might be dealing with this for several more months. Either way, I'm trying to be prepared for anything, and be cautious. At least he picked a good time to do this; would have been a lot tougher if I wasn't working from home.
 
Lisa & Oberon said:
. I think it's possible it got triggered when he was on Lantus for about 2 weeks last December, in which case it's been building for more like 11 months.
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His ss shows no insulin for about 7 months. Assuming that is the case, no insulin = no antibodies.
IAA is idiopathic-it arises spontaneously. Check out Doodles ss, January into February 2017 for an example. ​
Lisa & Oberon said:
Either way, I'm trying to be prepared for anything, and be cautious.
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Your instincts are good.
Lisa & Oberon said:
At least he picked a good time to do this; would have been a lot tougher if I wasn't working from home.
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I was fortunate to have been working from home when we were in the thick of it; and to have my domestic partner Dominick (aka the nightwatchman) 100% on board. It was a crazy time.
 
Not only did I pass on giving R midcycle, I'm skipping it now, too. He's holding steady in the mid 300s, and while it would probably be ok to give it to him, I really don't feel like staying up another 4+ hours to keep tabs on him. I'm beat after last night. So he got his 9.5 U of Lantus, but that's it. I'll do a bedtime check, though.
 
Sandy and Black Kitty said:
His ss shows no insulin for about 7 months. Assuming that is the case, no insulin = no antibodies.
IAA is idiopathic-it arises spontaneously. Check out Doodles ss, January into February 2017 for an example. ​

I was fortunate to have been working from home when we were in the thick of it; and to have my domestic partner Dominick (aka the nightwatchman) 100% on board. It was a crazy time.
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I'm wondering if it's anything like a classic immune response. Primary immune response to an initial antigen exposure (2 weeks of Lantus in Dec), formation of memory B cells, then a stronger secondary response when he got exposed again in July. In which case you're right, there wouldn't have been detectable antibodies present between Dec and July. Or the Dec exposure had nothing to do with it, and it's just random. Either way, IAA for the past 4 months or so, then. Might have a long way to go.

I'm lucky, too... I'm teaching/writing from home for the rest of the academic year and don't teach in the summer, so other than popping in to my lab occasionally I can be home most of the time for the next several months. And my husband is also teaching remotely at the moment and is an early bird. So we have good daily coverage for BG testing. (Last night I went to bed at 2 and he got up at 4.)
 
I hope you get that catch up sleep tonight. It's good to prioritize your health over a few better BG numbers.

Timing of IAA breaking is also a game of chance. Neko's seem to be starting to break just before we went for SRT for her acromegaly. She earned her first reduction just a couple days before we hit the road to Colorado. After SRT (which wasn't supposed to kick in for at least 2 weeks), reductions started coming right away and faster. I had to take one on the road back home. So the beginning of the break was about 7.5 months after she started insulin, Caninsulin for 2 months, then Lantus. I was lucky we had an experienced person from South Africa as a regular member then. She kept me company many of the late nights.
 
Lisa & Oberon said:
Not only did I pass on giving R midcycle, I'm skipping it now, too. He's holding steady in the mid 300s, and while it would probably be ok to give it to him, I really don't feel like staying up another 4+ hours to keep tabs on him. I'm beat after last night. So he got his 9.5 U of Lantus, but that's it. I'll do a bedtime check, though.
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All things considered I would have done the same and skipped the R. Considering the data form the past 2 weeks (any farther back is pretty much ancient history) yesterday was so dramatically out of pattern.

How long until your bedtime check? Todays flat cycle could signal an active cycle ahead (no bounce) ...or a bounce may be coming more slowly due to prolonged action from previously bound insulin having been released back into circulation. Either way good data gathering.
 
Sandy and Black Kitty said:
All things considered I would have done the same and skipped the R. Considering the data form the past 2 weeks (any farther back is pretty much ancient history) yesterday was so dramatically out of pattern.

How long until your bedtime check? Todays flat cycle could signal an active cycle ahead (no bounce) ...or a bounce may be coming more slowly due to prolonged action from previously bound insulin having been released back into circulation. Either way good data gathering.
Click to expand...

I'm probably going to check at +2 and then one last time whenever I go to bed. (I talk a good game about going to bed early, but usually end up staying up until midnight anyways...)

His overall pattern has been to spend most of his time in the 300s, give or take, with brief dips into the blues or sometimes greens that last maybe a couple of cycles, and then a high bounce before coming back to the 300s. Before we started R, the dips were coming every 10-14 days. Once I started using R, they started coming more frequently- every 3 or 4 days. This feels like an extension of that pattern, but deeper and longer than his previous dips, and (so far) without a big bounce. So I'm really not sure what to expect next.
 
And there's the bounce; he was just stalling. 433 at +3.75. I'm heading off to bed. Hopefully he won't go too terribly high tonight.
 
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