? Newly diagnosed, trying to get cat to gain weight

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Willow's paw is healed!
That is just the best news, Clare! :cat: I'm delighted - for both of you! :)


The vet also told me a few things that I wanted to get your opinion about:

1. Going above 2 units of insulin isn't a good idea for cats.
Utter horse feathers.

The only time going above two units would be bad for a cat is if the cat didn't actually need that much insulin.

A diabetic cat requires the insulin it requires. Some cats with 'high dose' conditions receive insulin doses that would make your vet's eyes water.


2. I should try not feeding her at all during the day to get her BG down- stick to the 8am/8pm food & insulin schedule.
Disagree.

'Frontloading' cats with large meals at the beginning of a cycle is necessary when using insulins that hit hard and fast after dose administration and peter out many hours before the next dose is due (e.g. Caninsulin/Vetsulin, Novolin N). The action profile of Lantus is very different. It has a gentler onset and typically does not drop BG like a rock when it kicks in. Lantus also typically has much longer duration than intermediates like Caninsulin and Novolin. Therefore, there is much greater freedom when it comes to feeding schedules for cats on Lantus and other long-acting insulins.

Feeding smaller, more frequent meals is less likely to spike BG levels during the cycle and can be easier on the pancreas. Some cats, for example those with pancreatitis, need to be fed little and often and that works well when paired with a long-acting insulin such as Lantus. For cats without complications receiving Lantus, it is best to get most, if not all, of the feeding done in the first half of each 12-hour cycle, but it's not strictly necessary. Food only needs to be withheld for the two hours before each preshot test so that the reading won't be food-influenced.


3. Using the syringe on the insulin pen is risky and I should buy the full bottle.
More horse feathers. Countless members here draw doses from insulin pens without any problem. Have done for years.

Cost-wise, the 10ml vials are usually wasteful: most cats need only small doses of Lantus and they would not use up all the insulin in a 10ml vial before it became unusable.


4. She also gave me some probiotic for her diarrhea, which I'll try.
Sensible course of action. If this probiotic works, great, but if it doesn't and it's not s. boulardii, I suggest trying the latter (and let your vet know you want to try it). Members here have had good results with it, and some reputable feline IBD internet groups also recommend it.


5. She suggested using the Libre Freestyle 14-day port.
Some members have had good experiences with the Libre, others not so much. It's a great idea in principle. When the Libre works it provides a lot of data. On the downside, each unit only lasts 14 days and there have been reports here that sometimes they stop working sooner than that. Also difficulty keeping it attached to the cat seems to be a common issue.

Even when using a Libre successfully, it's also necessary to still have a standard glucometer (e.g. you'd need one to test BG if the Libre failed or if it came off the cat).


A bubble usually forms in the syringe and I cannot get it out. How much does this change the amount of insulin in the syringe?
The change in amount would depend on the size of the bubble(s).

Try the following:

* Draw up about 1 - 1.5 units more than the dose you need (e.g. if giving a dose of 1 unit, draw up 2 - 2.5 units of insulin).

* Hold the syringe with the needle pointing upwards.

* Give the side of the syringe a series of flicks to move any bubbles up to the top of the barrel. If there are several small bubbles, try flicking the side of the syringe until the small bubbles 'pop' and form a single larger bubble (easier to remove).

* Keep the syringe needle pointed upwards and express most of the excess insulin. This should remove the air bubbles.

* Finish by doing the fine adjustment to set the required dose.

I am wondering what you all would do, given this advice ...
Go shopping for a vet with better FD knowledge?

I'm only half joking here. If Willow will need more than 2 units - and the data you've accumulated for Willow thus far looks to indicate this* - will your vet and yourself agree to disagree and will they support you going forwards? If you're happy with your vet in general and have a good relationship with them, then perhaps a bit of negotiation on treatment approach would help (e.g. can you try things the way you would like to work for a set period of time and then both of you review the situation?). Some vets are willing to learn together with their clients. If your vet were to take a 'my way or the highway' stance on insulin treatment and Mimi's health could potentially suffer as a consequence (poor regulation) then finding a more FD-savvy - or at least a more collaborative - vet may be necessary. When managing long-term health issues in our cats we need a supportive and collaborative relationship with our vets. It's tricky when the approach of the vet and the desired approach of the caregiver conflict.

My greatest concern here is about how much knowledge your vet currently has about feline diabetes and how much experience they have of treating the disease. The maximum 2 unit insulin dose for any cat is completely wrong (and it's the first and only time I've read a report here of a vet expressing such a view). The pen/vial thing is minor. It's easy to argue away that particular objection on cost grounds if necessary. The flawed approach to meeting a cat's insulin needs is a real biggie.

(* A caveat about the above comment on possible insulin requirements: with 1 unit jumps in dose it's possible to skip over the 'goldilocks' dose a particular cat needs at a particular time. I can't tell from the available data whether or not this caveat might apply in Willow's case (re the jump from 1 to 2 units), but it's something for you to be generally aware of. Any time you'd like feedback on how Willow's dose is working just give a shout out here.)


and given my ability to test Willow's BG 1-2 times per day.
This thread was written for people following the TR protocol but it contains some very helpful suggestions on how to fit testing around a busy schedule, regardless of which dosing protocol you're following:

Can You Do TR with a Full-time Job?


If there's any way you could snag some mid-cycle tests on the PM cycle that would help you. Even a few PM+2 tests could throw a little more light on how Mimi is doing.

Once again, Clare, I'm so happy Willow's paw is better. (((Willow))) :cat:


Mogs
.
 
Last edited:
That is just the best news, Clare! :cat: I'm delighted - for both of you! :)



Utter horse feathers.

The only time going above two units would be bad for a cat is if the cat didn't actually need that much insulin.

A diabetic cat requires the insulin it requires. Some cats with 'high dose' conditions receive insulin doses that would make your vet's eyes water.



Disagree.

'Frontloading' cats with large meals at the beginning of a cycle is necessary when using insulins that hit hard and fast after dose administration and peter out many hours before the next dose is due (e.g. Caninsulin/Vetsulin, Novolin N). The action profile of Lantus is very different. It has a gentler onset and typically does not drop BG like a rock when it kicks in. Lantus also typically has much longer duration than intermediates like Caninsulin and Novolin. Therefore, there is much greater freedom when it comes to feeding schedules for cats on Lantus and other long-acting insulins.

Feeding smaller, more frequent meals is less likely to spike BG levels during the cycle and can be easier on the pancreas. Some cats, for example those with pancreatitis, need to be fed little and often and that works well when paired with a long-acting insulin such as Lantus. For cats without complications receiving Lantus, it is best to get most, if not all, of the feeding done in the first half of each 12-hour cycle, but it's not strictly necessary. Food only needs to be withheld for the two hours before each preshot test so that the reading won't be food-influenced.



More horse feathers. Countless members here draw doses from insulin pens without any problem. Have done for years.

Cost-wise, the 10ml vials are usually wasteful: most cats need only small doses of Lantus and they would not use up all the insulin in a 10ml vial before it became unusable.



Sensible course of action. If this probiotic works, great, but if it doesn't and it's not s. boulardii, I suggest trying the latter (and let your vet know you want to try it). Members here have had good results with it, and some reputable feline IBD internet groups also recommend it.



Some members have had good experiences with the Libre, others not so much. It's a great idea in principle. When the Libre works it provides a lot of data. On the downside, each unit only lasts 14 days and there have been reports here that sometimes they stop working sooner than that. Also difficulty keeping it attached to the cat seems to be a common issue.

Even when using a Libre successfully, it's also necessary to still have a standard glucometer (e.g. you'd need one to test BG if the Libre failed or if it came off the cat).



The change in amount would depend on the size of the bubble(s).

Try the following:

* Draw up about 1 - 1.5 units more than the dose you need (e.g. if giving a dose of 1 unit, draw up 2 - 2.5 units of insulin).

* Hold the syringe with the needle pointing upwards.

* Give the side of the syringe a series of flicks to move any bubbles up to the top of the barrel. If there are several small bubbles, try flicking the side of the syringe until the small bubbles 'pop' and form a single larger bubble (easier to remove).

* Keep the syringe needle pointed upwards and express most of the excess insulin. This should remove the air bubbles.

* Finish by doing the fine adjustment to set the required dose.


Go shopping for a vet with better FD knowledge?

I'm only half joking here. If Willow will need more than 2 units - and the data you've accumulated for Willow thus far looks to indicate this* - will your vet and yourself agree to disagree and will they support you going forwards? If you're happy with your vet in general and have a good relationship with them, then perhaps a bit of negotiation on treatment approach would help (e.g. can you try things the way you would like to work for a set period of time and then both of you review the situation?). Some vets are willing to learn together with their clients. If your vet were to take a 'my way or the highway' stance on insulin treatment and Mimi's health could potentially suffer as a consequence (poor regulation) then finding a more FD-savvy - or at least a more collaborative - vet may be necessary. When managing long-term health issues in our cats we need a supportive and collaborative relationship with our vets. It's tricky when the approach of the vet and the desired approach of the caregiver conflict.

My greatest concern here is about how much knowledge your vet currently has about feline diabetes and how much experience they have of treating the disease. The maximum 2 unit insulin dose for any cat is completely wrong (and it's the first and only time I've read a report here of a vet expressing such a view). The pen/vial thing is minor. It's easy to argue away that particular objection on cost grounds if necessary. The flawed approach to meeting a cat's insulin needs is a real biggie.

(* A caveat about the above comment on possible insulin requirements: with 1 unit jumps in dose it's possible to skip over the 'goldilocks' dose a particular cat needs at a particular time. I can't tell from the available data whether or not this caveat might apply in Willow's case (re the jump from 1 to 2 units), but it's something for you to be generally aware of. Any time you'd like feedback on how Willow's dose is working just give a shout out here.)



This thread was written for people following the TR protocol but it contains some very helpful suggestions on how to fit testing around a busy schedule, regardless of which dosing protocol you're following:

Can You Do TR with a Full-time Job?


If there's any way you could snag some mid-cycle tests on the PM cycle that would help you. Even a few PM+2 tests could throw a little more light on how Mimi is doing.

Once again, Clare, I'm so happy Willow's paw is better. (((Willow))) :cat:


Mogs
.


Thank you for all of this advice. I will try to get more data from Willow. I work from home, but she doesn't enjoy the testing, and I am starting a new postdoc job which I have to devote a lot of energy toward.

I'm getting discouraged that Willow's BG hasn't budged despite changing her food and putting her on insulin (and increasing it). Reading this: https://www.felinediabetes.com/bg-curves.htm makes me feel overwhelmed, and I'm not sure if I will be able to figure this out, or if Willow can be regulated. I'm living in an expensive place and not making a lot of money, so I can't keep taking her back to the vet every week. If it's possible that too much insulin can also cause high BG, then I have absolutely no idea what to do!

But again, thank you so much for all of your advice- I would have even less of an idea what is going on without it.
 
We all have felt the same way. Trust has to be built. It will be. When you are overwhelmed come here to share. This is what we do. And believe me the fist day you FEEL success this pace will become HOME.

We WILL get through this together.

Keep up the good fight!
jeanne
 
Thanks for the encouragement. I was able to get her BG this morning before her food/shot, and then put some gabapentin in her food (vets prescribed this a year ago because she has developed a short fuse in old age-- she was on it during her curve at the vet in July so I hope it doesn't alter the readings) and will do a curve today.
 
Thank you for all of this advice. I will try to get more data from Willow. I work from home, but she doesn't enjoy the testing, and I am starting a new postdoc job which I have to devote a lot of energy toward.

I'm getting discouraged that Willow's BG hasn't budged despite changing her food and putting her on insulin (and increasing it). Reading this: https://www.felinediabetes.com/bg-curves.htm makes me feel overwhelmed, and I'm not sure if I will be able to figure this out, or if Willow can be regulated.

I don't know what your PhD is in, but I have a science background and I find that article rather overwhelming!

It's possible that Willow's BG readings are higher than they should owing to stress. When I took Maddie in for her first glucose curve, the graph was like a rollercoaster because she hates being at the vet's, so we'll be doing one at home this weekend (fingers crossed I can get the blood samples!). Maybe the best thing to do is to work on making the testing less stressful, rather than worrying about getting the perfect numbers right away? I know we all really want our kitties to be better RIGHT NOW KTHNXBAI, but as everyone here says so often, FD is a marathon, not a sprint.
 
Curve results are in, and they aren't great. It doesn't seem to be a curve at all. The BG ceiling has come down since diagnosis, but I can't break through the floor.

Any advice on dosing? Bring up/down? I'm afraid I don't want to consult the vet because I didn't follow any of her previous directions (except probiotics).
 
Hi Clare,

I'm going to tag @Chris & China (GA) to ask her to have a look at your spreadsheet when she's next online and hopefully she may be able to suggest a course of action.

FYI, Clare, I tend not to give dosing input unless I think a cat may be getting too much insulin. Also, there's a question mark in my mind about the jump from 1 to 2 units. Chris is a very experienced Lantus user and I think she may be able to better interpret your spreadsheet than I can. Very sorry I couldn't help on this one.


Mogs
.
 
Could still really use some advice here...

Have you read the Sticky on the different dosing methods and decided anything?

Also, I understand how overwhelming it is, especially at first, but we really do need to see at least 1 test on the PM cycle (other than the PMPS) Most cats go lower at night so it's important. Also, without testing on the PM cycle, you're literally missing half the picture. That's like trying to figure out what the puzzle picture is when you only have pieces filled in on one side.
 
Have you read the Sticky on the different dosing methods and decided anything?

Also, I understand how overwhelming it is, especially at first, but we really do need to see at least 1 test on the PM cycle (other than the PMPS) Most cats go lower at night so it's important. Also, without testing on the PM cycle, you're literally missing half the picture. That's like trying to figure out what the puzzle picture is when you only have pieces filled in on one side.
Thanks for the link. I had been looking for something like this but all I found was the 1995 article about curves, which emphasized the midpoint rather than the high or low point.

I will add some PM tests (can't test all night, though, realistically only up to +4hrs), but I still don't know what to do. I guess I'll try the SLGS method, which would have me increase her dose. Not sure if that's the right thing to do, but I'll try. Was hoping someone would have some insight on that.
 
I guess I'll try the SLGS method, which would have me increase her dose. Not sure if that's the right thing to do, but I'll try. Was hoping someone would have some insight on that.

TR would give her a better chance at remission. It does require a little more testing (and a lot more nerve) but on TR you only have to hold the dose for 6 cycles if it's not getting the results you want.

Reductions are earned when they drop below 50 and you have to learn to shoot lower and lower Pre-shot numbers. At first, if under 150, you'd stall, don't feed and test again in 20-30 minutes and use that time to post here with a clear subject line like "STALLING! NEED HELP!" (it usually works....LOL) Once you have someone's attention, you can go back and edit the subject line to the correct format. As you gain more experience and data, you gradually learn to shoot lower and lower pre-shots. When I had enough data and experience, I'd shoot China if she was above 50 (and you can see she was very tightly controlled on her spreadsheet)

On SLGS, you hold the dose for 7 days which means you have to hold the dose even if it's not getting the results you want which can lead to glucose toxicity where her body gets used to being in higher numbers even though you're giving insulin.

It's totally your decision so think about it, ask questions and when you decide, add it to your Signature. You can always change your mind if you want to!

All that being said, I think you could go up to 2.5 tomorrow.
 
Curve results are in, and they aren't great. It doesn't seem to be a curve at all. The BG ceiling has come down since diagnosis, but I can't break through the floor.

Any advice on dosing? Bring up/down? I'm afraid I don't want to consult the vet because I didn't follow any of her previous directions (except probiotics).
Vets advise you decide. I don't always follow advice and i usually give the vet a reason and i find they are fine with that. Afterall you know your cat best.
 
TR would give her a better chance at remission. It does require a little more testing (and a lot more nerve) but on TR you only have to hold the dose for 6 cycles if it's not getting the results you want.

Reductions are earned when they drop below 50 and you have to learn to shoot lower and lower Pre-shot numbers. At first, if under 150, you'd stall, don't feed and test again in 20-30 minutes and use that time to post here with a clear subject line like "STALLING! NEED HELP!" (it usually works....LOL) Once you have someone's attention, you can go back and edit the subject line to the correct format. As you gain more experience and data, you gradually learn to shoot lower and lower pre-shots. When I had enough data and experience, I'd shoot China if she was above 50 (and you can see she was very tightly controlled on her spreadsheet)

On SLGS, you hold the dose for 7 days which means you have to hold the dose even if it's not getting the results you want which can lead to glucose toxicity where her body gets used to being in higher numbers even though you're giving insulin.

It's totally your decision so think about it, ask questions and when you decide, add it to your Signature. You can always change your mind if you want to!

All that being said, I think you could go up to 2.5 tomorrow.
Thank you for the advice. TR does seem riskier, so I am wondering what the statistics are on how much better it is at achieving remission? All I saw was the 64% remission in the German cat owner trial.

Would it be possible to mix the two approaches at all? For example, increase her dose more often than every 7 days at first?
 
Would it be possible to mix the two approaches at all? For example, increase her dose more often than every 7 days at first?

No you can't mix them, but as long as you're willing and able to test enough, you can start on TR and switch to SLGS later (or you can start on SLGS and switch to TR later if you decide you want to be more aggressive)

Wow, her BG jumped this evening from 300s to 500s in 3 hours. Is this normal?

Yes, it can be totally normal....what did you feed when you fed the "snack at +6.5"?

Also, there's something we call New Dose Wonkiness (NDW)....it's when for some unknown reason, the first cycle or two after an increase, the numbers go up when you'd expect them to go down.

Tomorrow, why don't you go ahead and move over to the Lantus Forum? This thread is getting very long and people start to pass over really long threads because they figure somebody else is dealing with it. On the Lantus forum, you'll get help from people with lots of experience using the depot insulin's. Each day you start a new thread so it's not as easy to get lost.
 
Yes, it can be totally normal....what did you feed when you fed the "snack at +6.5"?

It was just part of the can that I space out over the day, like always.

Tomorrow, why don't you go ahead and move over to the Lantus Forum? This thread is getting very long and people start to pass over really long threads because they figure somebody else is dealing with it. On the Lantus forum, you'll get help from people with lots of experience using the depot insulin's. Each day you start a new thread so it's not as easy to get lost.

Oh I see, thanks!
 
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