Hi. I am so sorry to hear about the flares! NOT fun! Tomlin has required Prednisolone to manage his issues. Some cats may luck out and have one episode, which for some cats, they can be severe and require hospitalization, but then they never have another one. However, there are some cats who will develop chronic pancreatitis that is best managed with Prednisolone. Some will require it during a flare and be able to have it slowly discontinued just like with the other supportive meds, while others will need every other day dosing and for some, every day dosing is required for them to stay well. We tried and failed multiple times to slowly discontinue Prednisolone and manage Tomlin without every day dosing. The inflammation would creep back and he would have a flare. So, we found the most effective lowest dose to use when he is doing well and then we increase it slightly when he is in a flare. We also use Cerenia and add Zofran if needed to manage nausea and then Buprenex injectable to manage pain. Subq fluids are also helpful. If a cat is in a more severe flare, IV fluids at the hospital are a game changer. That is the only way to perfuse the pancreas. Sometimes it is an option to take them in for a 12 hour session and see how they do at home and if needed bring them back as Teresa did vs overnight hospitalization for days. It all depends on the severity of the flare.
The only other note is that there can be underlying GI issues that are aggravating or causing the pancreatitis. In that case, if the primary issue is IBD, depending on where in the GI tract the issue is, a drug like Budesonide vs Prednisolone can be helpful. Budesonide will target the gut and therefore **possibly have less of an effect on BG. The caveat is, depending on the gut health and the cat, Budesonide can sometimes have a greater systemic effect in one cat vs another and then you will see an increase in BG. There are mixed results with Budesonide but it is worth a try if there is evidence of a primary underlying GI issue causing the flares.
Stress and diet can definitely also be an issue so it is another ECID scenario where sometimes it’s trial and error to get to the bottom of the exacerbations as well as the management of flares with meds.