First the serious stuff. I hijacked Mowgli’s condo a few days ago
http://www.felinediabetes.com/FDMB/...-amps-272-pmps-265-2-196.216038/#post-2396418
Just a teaser of some of the trip pics. Still sorting over a thousand.
And I don’t canoe, or haven’t for years. Rowing is my thing.
OK, about the dose. A cat’s body and need for insulin can change over time. That means there is no one good dose, but the dose that is good for now. Neko’s “good” dose went from 8.75 units, down over time to about 0.75 units, then back up to 7 units, then down to about 0.25 units, all over 4.5 years. What I defined as a good dose was one did not take her too low, but maximized the amount of time under renal threshold. In the early days of 8.75 units, there was too much red/pink, but I couldn’t take the dose higher and keep her safe. Over time she got less bouncy, and the good dose, at the time, meant she spend most of her time in blue/green. Neko was an acrocat, so I was not looking to earn reductions, because her pancreas was not healing. In fact, I saw evidence at times that it was working just fine.
I learned to not focus on what the size of the dose was, but to look at what sort of blood sugar numbers Neko was seeing, and adjusted the dose to get the BGs I wanted. The last several months I also had to factor in other medical conditions and medications and her appetite, which had some impact on blood sugars and made it more challenging to keep her safe.
Some cats achieve what we call a breakthrough dose, where they hit a particular dose that starts the process of pancreatic healing, and a series of reductions begins. That wasn’t, of course, what caused Neko’s reductions. In her case it was treating the acromegaly and her antibodies breaking.
Will see how to apply this for my Ti-Mousse and what this breakthrough dose is!! 
thanks 