10/2/18 Olive AMPS 309; +3=297; +5.5=216; +9=177; PMPS 200; +4=228; +5.5=195; +11=188

Olive & Paula

Olive & Paula

Very Active Member
Yesterday

So took SCS (small chicken shot) . Since we will be out late this morning. Also didn't want her bloodwork tomorrow to get skewed to much. I guess we go to 8.5 u unless someone tells me otherwise. The 8.95 really didn't have time to establish on the 30th. So don't know what to think of the 8.75 last night. She really has me guessing.
 
Hey Paula,
That was some night you had with Olive.

Usually with doses above 5u you would do reductions in 0.5u steps, changing the dose at 0.25u stetps is more aking to shaving the dose. I get that Olive has multiple health issues, and that on the surface she seems to respond to small dose changes.
I have some concerns when you don't take a full reduction when she drops below 40, I worry if this may push her BG to far.
The tumour in acro can wax and wane and impact the BG, if it's in a waning phase, and you are not taking the full reduction you might really find yourself having to fight very hard to keep BG up. Low numbers two nights in a row (low 40's and 30's), may be Olive trying to tell you something.

I haven't been following Olive closely and no personal experience with Acro or high doses, I'm going to tag @Wendy&Neko she can tell us if I'm just being a worry wart, or if your approach seems sensible.
 
Gill & George said:
Hey Paula,
That was some night you had with Olive.

Usually with doses above 5u you would do reductions in 0.5u steps, changing the dose at 0.25u stetps is more aking to shaving the dose. I get that Olive has multiple health issues, and that on the surface she seems to respond to small dose changes.
I have some concerns when you don't take a full reduction when she drops below 40, I worry if this may push her BG to far.
The tumour in acro can wax and wane and impact the BG, if it's in a waning phase, and you are not taking the full reduction you might really find yourself having to fight very hard to keep BG up. Low numbers two nights in a row (low 40's and 30's), may be Olive trying to tell you something.

I haven't been following Olive closely and no personal experience with Acro or high doses, I'm going to tag @Wendy&Neko she can tell us if I'm just being a worry wart, or if your approach seems sensible.
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Gill, thanks for response. We found out 9 units is to much but 8. 75 isn't quite enough. We tried 8.85 but she had a day of not eating and vomiting and went back down to 8.75. After about 8 cycles she starts to petter out on a dose and starts rising again. I know about the half units but now it's to much when increasing. It worked well until we hit 8.5 mark. Now just trying to find tune to get her to stay longer in green.

Wendy has been helping me. She actually suggested a one time big chicken shot which I didn't quite take as much as she suggested. After 3 months of discussions with 2 vets we are finally getting cabergoline which should arrive this week. Tomorrow she is getting baseline bloodwork and I don't want that to be to skewed up. I don't know if that's logical thinking on my part of not. I will probably go to 8.5 tonight. It does seem that bit of extra at this time works versus half or full unit increases. If cabergoline works it could get exciting.
 
Gill & George said:
That's what was worrying me.
She's not an easy case is she?:rolleyes:
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Is any cat easy :rolleyes:. Been thinking while doing my errands, maybe I will do 8.25 (the half unit reducie) or keep it at 8 and see what the cabergoline does. But I don't think it works that fast and I don't want her to get out of control either. It's taken 8 months to get here. It seems like a catch 22 right now. Can leave her at 8 and see what Dr says tomorrow, but she knows as much as me, which is nothing. Uncharted territory here for both of us.
 
Olive & Paula said:
If cabergoline works it could get exciting.
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Truer words never spoken. It does seem to take a week or two to start working, but when it does, hold onto your seat! Reduction rules get thrown out the window and you'll need to err on the side of caution. Which means larger reductions than "normal", possibly back to back reduction, much larger BCS than what you've done. Note for any lurkers, this is only for acromegalic cats who are treating the tumour, such as giving cabergoline or having SRT would do.

I think doing 8.25 for the moment would be a good comprimise. It is possible the acro tumour is changing on it's own. Many a time I said "I'll go back up if I need to" and didn't.
 
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