Molly's BG is staying high recently

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Sue Hammond

Member Since 2017
BG tests remain high, I haven't changed diet, shes been on Mac's and Lily's kitchen wet food from day 1, her routine hasn't changed, she seems well in herself, , no abnormal drinking or weeing, she seems happy, it's just dissapointing when in the past she's been much lower, she's having 2u twice a day...maybe it isn't enough? Any advice please, thank you xx
 
Definitly time for a dose increase. Try 2.5 for a few days and let's see what happens. Insulin needs change.
 
Definitly time for a dose increase. Try 2.5 for a few days and let's see what happens. Insulin needs change.
She's never had a dose that high before though, so a bit worried about increasing it, she's lost all her excess weight, and I was hoping that would have made a significant difference to her doses, but apparently not
 
Hi Sue,

Perhaps a vet checkup might be a good idea. Tooth and gum problems are notorious offenders for driving BG up, as can other infectious or inflammatory processes in the body (plus diabetics may be more vulnerable to infection; healing may certainly take longer). My vet told me that diabetics tend to be very prone to gingivitis (and more vulnerable to infection in general). Also, I see that Molly seems to be spending a fair amount of time above the renal threshold. Sugary urine may make a kitty more susceptible to urinary infections.

If you're not already doing so, it would be a good idea to keep a regular check on Molly's urine to make sure she's negative for ketones while you try to identify other factors which may be elevating BG levels.

I see from Molly's spreadsheet that she can get some very steep drops on her Caninsulin. It might be worth discussing a switch to an insulin with a gentler action profile with a view to improving Molly's overall regulation (e.g. Lantus, Levemir or Prozinc). Gentler-acting insulins typically don't tend to produce such wide swings in BG level (though every cat is different) and it can assist with finding a suitable amount of insulin to keep a kitty below the renal threshold most, if not all, of the time but still in safe numbers at nadir.


Mogs
.
 
Hi Sue,

Perhaps a vet checkup might be a good idea. Tooth and gum problems are notorious offenders for driving BG up, as can other infectious or inflammatory processes in the body (plus diabetics may be more vulnerable to infection; healing may certainly take longer). My vet told me that diabetics tend to be very prone to gingivitis (and more vulnerable to infection in general). Also, I see that Molly seems to be spending a fair amount of time above the renal threshold. Sugary urine may make a kitty more susceptible to urinary infections.

If you're not already doing so, it would be a good idea to keep a regular check on Molly's urine to make sure she's negative for ketones while you try to identify other factors which may be elevating BG levels.

I see from Molly's spreadsheet that she can get some very steep drops on her Caninsulin. It might be worth discussing a switch to an insulin with a gentler action profile with a view to improving Molly's overall regulation (e.g. Lantus, Levemir or Prozinc). Gentler-acting insulins typically don't tend to produce such wide swings in BG level (though every cat is different) and it can assist with finding a suitable amount of insulin to keep a kitty below the renal threshold most, if not all, of the time but still in safe numbers at nadir.


Mogs
.
Hi
Molly had a check up with the Vet two weeks ago, when she had her boosters and health check, her teeth and gums are good and her urine test was good...so I've no idea what's going on...My vet isn't keen on prescribing different insulin, he wants to stick to Caninsulin I've already asked if maybe a different one would be better, he said he's not happy to change her to another just yet... She's been high since having her booster vaccinations, could that have anything to do with her bg results xx
 
Hi Sue,

Perhaps a vet checkup might be a good idea. Tooth and gum problems are notorious offenders for driving BG up, as can other infectious or inflammatory processes in the body (plus diabetics may be more vulnerable to infection; healing may certainly take longer). My vet told me that diabetics tend to be very prone to gingivitis (and more vulnerable to infection in general). Also, I see that Molly seems to be spending a fair amount of time above the renal threshold. Sugary urine may make a kitty more susceptible to urinary infections.

If you're not already doing so, it would be a good idea to keep a regular check on Molly's urine to make sure she's negative for ketones while you try to identify other factors which may be elevating BG levels.

I see from Molly's spreadsheet that she can get some very steep drops on her Caninsulin. It might be worth discussing a switch to an insulin with a gentler action profile with a view to improving Molly's overall regulation (e.g. Lantus, Levemir or Prozinc). Gentler-acting insulins typically don't tend to produce such wide swings in BG level (though every cat is different) and it can assist with finding a suitable amount of insulin to keep a kitty below the renal threshold most, if not all, of the time but still in safe numbers at nadir.


Mogs
.
She's not weeing or drinking abnormally either, her appetite is normal, her coat is glossy, no dandruff which she had when first diagnosed... She's alert and playful xx
 
I'd hoped that with her losing her excess weight, around 5lbs, that would have made a significant difference to her Diabetes, but its made no difference at all... I'm wondering if I should have a stricter feeding timetable, because at the moment I've been feeding little and often, several times a day..and leaving food down when I'm not here in case she goes low, which she has on the odd occasion in the past...
 
ITs definitely better! Ideally you want to get her under 7. You can use syringes with the pen. Just use the pen as a mini vial.
What I meant was I don't have any syringes I had a look at one, but I can't see the measurements, they went up in .5, not .25....Would it be better to have a stricter feeding routine, rather than having small meals several times a day, have just 2 maybe? The trouble is she only eats very little at a time, so could end up by evening very hungry, and I have two cats, so could be difficult
 
What I meant was I don't have any syringes I had a look at one, but I can't see the measurements, they went up in .5, not .25....Would it be better to have a stricter feeding routine, rather than having small meals several times a day, have just 2 maybe? The trouble is she only eats very little at a time, so could end up by evening very hungry, and I have two cats, so could be difficult
U40's have half unit markings but not 0.25... But if you go half way between the whole number and half line, that's 0.25. Syringes that hold only 3/10 cc are easier to see. A magnifying glass may help if it's still hard to see.

These are the ones I use https://www.adwdiabetes.com/product/18553/ulticare-u40-pet-29g-3-10cc-1-2in-half-unit
 
I've just done another test +6 is 21.9, I really don't understand these results at all..:(
Probably a bit of a bounce. Your cat isn't used to being in lower numbers so the body is releasing stored glucose to protect itself. Hopefully once her body adjusts to lower numbers some of the bouncing will subside. I understand how frustrating it is. But on the positive side, yeah for a blue number today!
 
What I don't understand is her bg is high, but she's not drinking or weeing more than a non Diabetic cat, surely if there was this much glucose in her, she would be urinating frequently and drinking more too, as she was before diagnosis...Her last urine test was normal too
 
What I don't understand is her bg is high, but she's not drinking or weeing more than a non Diabetic cat, surely if there was this much glucose in her, she would be urinating frequently and drinking more too, as she was before diagnosis...Her last urine test was normal too
She is probably getting most of the water she needs from her food. You are giving her insulin so she's feeling better... So that's a great thing!
 
I just can't help thinking she's never going to get better, and that makes me think her life will be cut short because if it...
 
Can you add what kind of food you're feeding to your signature? To answer your questions about food from before, most find several smaller meals to work better then just two larger meals, so keep doing what you're doing.
Added.....She has mostly Mac's wet canned food, and occasionally Lily's kitchen
 
@Sue Hammond

Hi Sue, I think there may be a couple of things going on.
I think Molly is getting some bouncing (from numbers dropping too fast and/or too low for her comfort); and I also think she's not getting good duration from the Caninsulin, so this is possibly exacerbating the bounce problem (the numbers are going higher than they otherwise might, and maybe for longer).

It may well be that a gentler, longer-lasting insulin would suit Molly better. However, we've talked about this before and I know there are some things that mean this isn't currently possible:
1. Your current vet doesn't want to change insulin.
2. You don't feel able to use syringes (because of your vision problem).

A different vet may well be willing to prescribe a different insulin.
And maybe it's worth just practicing using the syringes that you have (the ones with .5 unit markings) by drawing up coloured water into them. I practiced on oranges when I first started injecting, and quite a few people do that. It may be that using syringes isn't going to be as hard as you imagine. But if it is too difficult, then at least you'll know you gave it your best shot (no pun intended! ;) ).

If none of the above is possible then your only option, with regard to insulin, will be to experiment with the Caninsulin dose to find out what works best for Molly at any given time. And it may well be that her numbers do even out over time.

It might also be worth experimenting with different foods. Some cats are quite sensitive to foods for all kinds of reasons (carb sensitivity, or sensitivity to one or other of the ingredients), and their BG can spike as a result of that.

It's still relatively 'early days' so there's every chance that Molly's BG situation can and will improve.
And there have certainly been improvements in Molly's health since she's been on insulin, despite the fluctuating numbers. This is really good news. :bighug:

Eliz
 
@Sue Hammond

Hi Sue, I think there may be a couple of things going on.
I think Molly is getting some bouncing (from numbers dropping too fast and/or too low for her comfort); and I also think she's not getting good duration from the Caninsulin, so this is possibly exacerbating the bounce problem (the numbers are going higher than they otherwise might, and maybe for longer).

It may well be that a gentler, longer-lasting insulin would suit Molly better. However, we've talked about this before and I know there are some things that mean this isn't currently possible:
1. Your current vet doesn't want to change insulin.
2. You don't feel able to use syringes (because of your vision problem).

A different vet may well be willing to prescribe a different insulin.
And maybe it's worth just practicing using the syringes that you have (the ones with .5 unit markings) by drawing up coloured water into them. I practiced on oranges when I first started injecting, and quite a few people do that. It may be that using syringes isn't going to be as hard as you imagine. But if it is too difficult, then at least you'll know you gave it your best shot (no pun intended! ;) ).

If none of the above is possible then your only option, with regard to insulin, will be to experiment with the Caninsulin dose to find out what works best for Molly at any given time. And it may well be that her numbers do even out over time.

It might also be worth experimenting with different foods. Some cats are quite sensitive to foods for all kinds of reasons (carb sensitivity, or sensitivity to one or other of the ingredients), and their BG can spike as a result of that.

It's still relatively 'early days' so there's every chance that Molly's BG situation can and will improve.
And there have certainly been improvements in Molly's health since she's been on insulin, despite the fluctuating numbers. This is really good news. :bighug:

Eliz
Hi Eliz,@Elizabeth and Bertie
I feel like I'm at my wit's end to be honest with you, I really feel like it's all going wrong for Molly....I have been feeding Mac's and the occasional Lily's kitchen, the same variety's, which are both low carb, high protein, and high moisture content, I haven't changed her diet at all since she was first diagnosed...Maybe I should increase to 2.5u but only when I can be home all day to watch her and test several times a day...I'd worry about giving 2.5u at night in case she dropped too low during the night, sometimes on the odd occasion she has been as low as 5 pre am shot, so giving 2.5 could send her crashing, that's my only worry :(
 
@Sue Hammond

Hi Sue, I think there may be a couple of things going on.
I think Molly is getting some bouncing (from numbers dropping too fast and/or too low for her comfort); and I also think she's not getting good duration from the Caninsulin, so this is possibly exacerbating the bounce problem (the numbers are going higher than they otherwise might, and maybe for longer).

It may well be that a gentler, longer-lasting insulin would suit Molly better. However, we've talked about this before and I know there are some things that mean this isn't currently possible:
1. Your current vet doesn't want to change insulin.
2. You don't feel able to use syringes (because of your vision problem).

A different vet may well be willing to prescribe a different insulin.
And maybe it's worth just practicing using the syringes that you have (the ones with .5 unit markings) by drawing up coloured water into them. I practiced on oranges when I first started injecting, and quite a few people do that. It may be that using syringes isn't going to be as hard as you imagine. But if it is too difficult, then at least you'll know you gave it your best shot (no pun intended! ;) ).

If none of the above is possible then your only option, with regard to insulin, will be to experiment with the Caninsulin dose to find out what works best for Molly at any given time. And it may well be that her numbers do even out over time.

It might also be worth experimenting with different foods. Some cats are quite sensitive to foods for all kinds of reasons (carb sensitivity, or sensitivity to one or other of the ingredients), and their BG can spike as a result of that.

It's still relatively 'early days' so there's every chance that Molly's BG situation can and will improve.
And there have certainly been improvements in Molly's health since she's been on insulin, despite the fluctuating numbers. This is really good news. :bighug:

Eliz
@Elizabeth and Bertie we don't have another Vet in our town, and I don't drive, so it would be difficult travelling on a bus carrying her, and also more stressful, so we'll have to stick to our current Vet I'm afraid
 
Hi Eliz,@Elizabeth and Bertie
I feel like I'm at my wit's end to be honest with you, I really feel like it's all going wrong for Molly....I have been feeding Mac's and the occasional Lily's kitchen, the same variety's, which are both low carb, high protein, and high moisture content, I haven't changed her diet at all since she was first diagnosed...Maybe I should increase to 2.5u but only when I can be home all day to watch her and test several times a day...I'd worry about giving 2.5u at night in case she dropped too low during the night, sometimes on the odd occasion she has been as low as 5 pre am shot, so giving 2.5 could send her crashing, that's my only worry :(
I dose my own cat more aggressively when I am home and more conservatively when I am not. I can’t test at all during the day because I work. (In home this week for winter break). So I do a little less then I would give otherwise. In the evening in home, so unless I'm really tired and not sure I can be up, I dose a little more aggressively.

Your other option, but it doesn't work for most people's schedule, is to dose smaller doses three times a day. So instead of 2-2.5 units twice a day you would do like 1.5 units 3 times a day every 8 hours. That's a pain in the ass though.
 
I dose my own cat more aggressively when I am home and more conservatively when I am not. I can’t test at all during the day because I work. (In home this week for winter break). So I do a little less then I would give otherwise. In the evening in home, so unless I'm really tired and not sure I can be up, I dose a little more aggressively.

Your other option, but it doesn't work for most people's schedule, is to dose smaller doses three times a day. So instead of 2-2.5 units twice a day you would do like 1.5 units 3 times a day every 8 hours. That's a pain in the ass though.
I think that's what I'm going to have to do, but I'm out most of tomorrow so will start 2.5 on Tuesday when I'll be home all day, if her am test is high. Dosing every 8 hours won't be very convenient really, but it would probably be better for Molly... I'm going to email her spreadsheet to my vet on Tuesday, see what he says about maybe changing her Insulin, but I'm pretty sure it'll be a no again
 
Dosing every 8 hours won't be very convenient really,
Dosing every 8 hours can be a complete an utter nightmare and takes an extraordinary amount of work on the part of the caregiver to keep the cat safe. I've seen a few members here go through it and it's not something I'd recommend undertaking unless there was a dire medical necessity to do so.

we don't have another Vet in our town, and I don't drive, so it would be difficult travelling on a bus carrying her, and also more stressful, so we'll have to stick to our current Vet I'm afraid

I'm going to email her spreadsheet to my vet on Tuesday, see what he says about maybe changing her Insulin, but I'm pretty sure it'll be a no again

Perhaps request that your vet asks an external feline diabetes specialist to review Molly's case - or to refer you to one for a consult - because that might help you to secure an Rx for a different, longer-acting insulin. Our vets routinely consult external specialists when the occasion calls for it. It may not even be necessary for you to travel.

Are you in the UK, Sue? If yes, I'd suggest the Feline Diabetes Clinic in the Royal Veterinary College (Herts). They have done extensive trials with Prozinc which is now the next insulin a UK vet is legally obliged to try if Caninsulin proves ineffective. If the external referral is agreed then it helps to provide them with a brief journal of clinical signs as well as Molly's BG spreadsheet data. Note things like general behaviour and sociability, energy levels (e.g. sleepy/lethargic when insulin is at peak effect?), appetite, GI upsets (if any), peeing, pooping, drinking, etc.

(Note: Based on my experiences with their consultants I wouldn't recommend referral to the feline diabetes specialists at Langford Vet School in Bristol. I found them very backward and inflexible in their approach to feline diabetes - and I had no hesitation telling our own vet how unhappy I was with them. FWIW, the vets at Langford did do a great job with my civvie's radioiodine treatment, but they suck when it comes to FD.)

Sending out positive vibes for your vet to be amenable to the insulin switch.


Mogs
.
 
Dosing every 8 hours can be a complete an utter nightmare and takes an extraordinary amount of work on the part of the caregiver to keep the cat safe. I've seen a few members here go through it and it's not something I'd recommend undertaking unless there was a dire medical necessity to do so.
Hi, yes I'm in the UK, but travelling would be difficult as I don't drive, and wouldn't want to carry Molly on public transport...My Vet has, (so he says) done specialist courses in FD, so I don't know if he would refer me or not..He did speak of a specialist, but it was North of London somewhere, and residential....The other thing is Molly's insurance wouldn't be enough to cover it, as only one claim per illness can be claimed per year, and she's made a dent in hat already with claims....I will send my Vet the spreadsheet and see where we go from there....Thank you very much for your advice, let's hope my Vet approves Prozinc...xx
Sue




Perhaps request that your vet asks an external feline diabetes specialist to review Molly's case - or to refer you to one for a consult - because that might help you to secure an Rx for a different, longer-acting insulin. Our vets routinely consult external specialists when the occasion calls for it. It may not even be necessary for you to travel.

Are you in the UK, Sue? If yes, I'd suggest the Feline Diabetes Clinic in the Royal Veterinary College (Herts). They have done extensive trials with Prozinc which is now the next insulin a UK vet is legally obliged to try if Caninsulin proves ineffective. If the external referral is agreed then it helps to provide them with a brief journal of clinical signs as well as Molly's BG spreadsheet data. Note things like general behaviour and sociability, energy levels (e.g. sleepy/lethargic when insulin is at peak effect?), appetite, GI upsets (if any), peeing, pooping, drinking, etc.

(Note: Based on my experiences with their consultants I wouldn't recommend referral to the feline diabetes specialists at Langford Vet School in Bristol. I found them very backward and inflexible in their approach to feline diabetes - and I had no hesitation telling our own vet how unhappy I was with them. FWIW, the vets at Langford did do a great job with my civvie's radioiodine treatment, but they suck when it comes to FD.)

Sending out positive vibes for your vet to be amenable to the insulin switch.


Mogs
.
 
Just joining in to say we have some U100 syringes (need to use conversion chart) to enable more small increment dosing changes if you would like to try them. Others will be able to support with advice in the use of U100' s if you are unsure. If you are in UK we could arrange to post them (only asking for postage costs) if this would help. Just a thought.
 
Just joining in to say we have some U100 syringes (need to use conversion chart) to enable more small increment dosing changes if you would like to try them. Others will be able to support with advice in the use of U100' s if you are unsure. If you are in UK we could arrange to post them (only asking for postage costs) if this would help. Just a thought.
Thank you very much for your kind offer, I'll send the spreadsheet to my Vet, and see where we go from there first, then I'll get back to you, thank you xxx
 
Thank you very much for your kind offer, I'll send the spreadsheet to my Vet, and see where we go from there first, then I'll get back to you, thank you xxx
No problem, wait to hear if you would like to try after vet advice. Our experience was that vet won't necessarily suggest alternative syringes but was happy once she knew we had researched and were using the conversion chart.
 
No problem, wait to hear if you would like to try after vet advice. Our experience was that vet won't necessarily suggest alternative syringes but was happy once she knew we had researched and were using the conversion chart.
I really don't like syringes tbh, as my sight isn't great drawing up the dose, even with a magnifying glass , and also have never been shown properly how to use them... I've only ever used a Vetpen....I know with prozinc it'll be syringes, so I guess one way or another I'll have to get used to them, I'm just terrified of giving the wrong dose..x
 
I really don't like syringes tbh, as my sight isn't great drawing up the dose, even with a magnifying glass , and also have never been shown properly how to use them... I've only ever used a Vetpen....I know with prozinc it'll be syringes, so I guess one way or another I'll have to get used to them, I'm just terrified of giving the wrong dose..x
Totally know where you are at. We went straight to syringes so don't know about vet pen. But found the u100' s not too bad. It really does get easier the more practice you have. I used to double and triple check before injecting!. Once you start to feel a little more confident with how Molly reacts to doses and can perhaps adjust more precisely you will feel happier I think.
 
Totally know where you are at. We went straight to syringes so don't know about vet pen. But found the u100' s not too bad. It really does get easier the more practice you have. I used to double and triple check before injecting!. Once you start to feel a little more confident with how Molly reacts to doses and can perhaps adjust more precisely you will feel happier I think.
Is it easy to convert to u100 syringes
 
Is it easy to convert to u100 syringes
Yes you use a conversion chart would send you a copy with syringes. Very easy. We worried when we thought about doing it but it really is no problem and ultimately gives you greater control and safety.
 
However we only ever used Caninsulin. You would need to check with others on here re the use of u100's with Prozinc ( as I do not have experience to advise on that at all).
 
However we only ever used Caninsulin. You would need to check with others on here re the use of u100's with Prozinc ( as I do not have experience to advise on that at all).
How have you found Caninsulin, have you had good results with it
 
How have you found Caninsulin, have you had good results with it
A difficult question. Lila was 16y at diagnosis and at times I think it was ok. But we never achieved good regulation consistently. In hindsight a different insulin may have helped. But Molly is an individual and it really is difficult to generalise. Take a step at a time and be guided by the wealth of advice that people have on here and of course by your vet (but don't be afraid to research +++ and question your vet as you will quickly realise that there are gaps in vets experiences of diabetes).
 
Dosing every 8 hours can be a complete an utter nightmare and takes an extraordinary amount of work on the part of the caregiver to keep the cat safe. I've seen a few members here go through it and it's not something I'd recommend undertaking unless there was a dire medical necessity to do so.





Perhaps request that your vet asks an external feline diabetes specialist to review Molly's case - or to refer you to one for a consult - because that might help you to secure an Rx for a different, longer-acting insulin. Our vets routinely consult external specialists when the occasion calls for it. It may not even be necessary for you to travel.

Are you in the UK, Sue? If yes, I'd suggest the Feline Diabetes Clinic in the Royal Veterinary College (Herts). They have done extensive trials with Prozinc which is now the next insulin a UK vet is legally obliged to try if Caninsulin proves ineffective. If the external referral is agreed then it helps to provide them with a brief journal of clinical signs as well as Molly's BG spreadsheet data. Note things like general behaviour and sociability, energy levels (e.g. sleepy/lethargic when insulin is at peak effect?), appetite, GI upsets (if any), peeing, pooping, drinking, etc.

(Note: Based on my experiences with their consultants I wouldn't recommend referral to the feline diabetes specialists at Langford Vet School in Bristol. I found them very backward and inflexible in their approach to feline diabetes - and I had no hesitation telling our own vet how unhappy I was with them. FWIW, the vets at Langford did do a great job with my civvie's radioiodine treatment, but they suck when it comes to FD.)

Sending out positive vibes for your vet to be amenable to the insulin switch.


Mogs
.
A difficult question. Lila was 16y at diagnosis and at times I think it was ok. But we never achieved good regulation consistently. In hindsight a different insulin may have helped. But Molly is an individual and it really is difficult to generalise. Take a step at a time and be guided by the wealth of advice that people have on here and of course by your vet (but don't be afraid to research +++ and question your vet as you will quickly realise that there are gaps in vets experiences of diabetes).
It's all very confusing isn't it,. I hoped by now after 4 months she would have settled a bit, I know it's still early days, she has had the occasional yellow sometimes blue and even though rarely has been n the green for her amps test, but the next morning it's up in the pinks again, that's what I'm having problems understanding, why it's fluctuating so much..We had a period of being in the blues for a few days only some weeks ago...When we took Molly to the Vet a couple of weeks ago he said she's doing well, so I really don't think after saying that he will change her to prozinc..
 
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