03/15 Gizmo PMPS=270, +2=242, +4=209, +5.5=189, +6.5=196, +11=166

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@Marje and Gracie

What is your opinion of Epakitin? It contains Lactose, but now sure how much and not sure if it could be given to a diabetic cat.
http://www.vetoquinolusa.com/content/epakitin

Or more specifically Chitosan? (https://smile.amazon.com/NOW-Foods-Chitosan-500mg-Caps/dp/B0013OSLWG/?tag=felinediabetesfdmb-20)
http://franklintnvet.com/chitosan-renal-failure-treatment/
A veterinary-specific formula called Epakitin is now available. Epakitin is a chitosan-based phosphate binder and uremic reducer. This product has been clinically proven to reduce urea, creatinine, calcium absorption and decrease phosphatemia leading to an increase in life expectancy without affecting food consumption. Epakitin is reported to prevent future kidney damage and improve the pet’s quality of life. (Plain Chitosan can be given in place of Epakitin.) The side effects of Epakitin have been mild and include lack of appetite, behavior changes, lethargy, and hypercalcemia (if higher than the recommended dose is adminstered). The recommended dosage is 1g/5kg of body weight given orally in the morning and in the evening with food.
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LizzieInTexas said:
@Marje and Gracie

What is your opinion of Epakitin? It contains Lactose, but now sure how much and not sure if it could be given to a diabetic cat.
http://www.vetoquinolusa.com/content/epakitin

Or more specifically Chitosan? (https://smile.amazon.com/NOW-Foods-Chitosan-500mg-Caps/dp/B0013OSLWG/?tag=felinediabetesfdmb-20)
http://franklintnvet.com/chitosan-renal-failure-treatment/
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I don't remember if you are using it as a P binder or as an absorbent of uremic toxins. I'm sorry, but I am also helping several members with CKD and so I don't always remember who has low calcium, who has high, who is using what binder for what reason, etc.

If you are using it as a binder, I prefer aluminum hydroxide powder. It won't affect the BG and is tasteless.
 
Marje and Gracie said:
I don't always remember who has low calcium, who has high, who is using what binder for what reason, etc.
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I know you are really busy - I appreciate it.

I am NOT currently using Epakitin or Chitosan. I was reading over at Tanya's and ran across it and was doing a bit of research.

I am not using any phosphorus binder.

"This product has been clinically proven to reduce urea, creatinine, calcium absorption and decrease phosphatemia leading to an increase in life expectancy without affecting food consumption. Epakitin is reported to prevent future kidney damage and improve the pet’s quality of life."

So I was wondering if it would be a good addition to Gizmo's regiment. I was wondering if it acting as a binder would be a bonus benefit. After I read that Epakitin had Lactose I started researching the active ingredient (Chitosan).

Labs Tab is current on SS (02/14/17 is last BW)
BUN 51
Creatinine 3.3
BUN/Creat ratio 15.5
Calcium 10.6
Phos 5
 
You have to be careful when someone says something is "clinically proven". It might be clinically proven in lab mice but not cats. Or "clinically proven" might be that a small study that was done showed it helped. The study done was a small study in 1995 where CRF was induced in mice.

Will it help? Maybe but chitosan is a sugar soypu might see the BG rise.
 
Marje and Gracie said:
You have to be careful when someone says something is "clinically proven". It might be clinically proven in lab mice but not cats. Or "clinically proven" might be that a small study that was done showed it helped. The study done was a small study in 1995 where CRF was induced in mice.

Will it help? Maybe but chitosan is a sugar soypu might see the BG rise.
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Thank you. Juggling FD and CKD is a real challenge. Especially the phosphorus/food issue. I am really trying to stay away from the fish/seafood that is low carb/low phos but I may just relent - I am about out of other options (other than raw or making my own raw - neither is a good option for me).
 
LizzieInTexas said:
Thank you. Juggling FD and CKD is a real challenge. Especially the phosphorus/food issue. I am really trying to stay away from the fish/seafood that is low carb/low phos but I may just relent - I am about out of other options (other than raw or making my own raw - neither is a good option for me).
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I would stay away from fish. There are lots of foods on the low carb/low P link. Usually binders are started when the P is 6 or the P x Ca is greater than 70.
 
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