Once you know the food is no longer influencing her rise in BG numbers, like going 2 hours without food and still seeing her numbers continue to rise, and she is safe to shoot (above 50), you could give her the dose, but that would affect your shot schedule. Your new shot schedule would be 12 hours after you gave the insulin. You could work the shot schedule back by 15 minutes per cycle or 30 minutes per day, to get back to your preferred or regular shot time. My shot schedule was never that flexible, but maybe yours is.