Darn it! Mogs you were correct 2 is way too much!
I am always super cautious about my own little one and I extend that caution to the kitties here. I don't know much about Novolin at all but, like Lucy (
@Squalliesmom), Saoirse's first insulin was Caninsulin (a.k.a. Vetsulin). Caninsulin's action can be very harsh and, like Novolin, it can drop BG like a rock so I do have some experience of massive BG drops
and the impact of changing diet from w/d to a low carb food through my treatment of Saoirse.
In the early stages of Saoirse's treatment when I was transitioning Saoirse to low carb food from w/d (the dry version - even higher in carbs than the w/d canned) I wanted to reduce the dose to leave a safety cushion so that Saoirse would not go too low, as I had no idea of how the reduction in carbs would affect her BG levels but I had read the warnings. (Dr Lisa Pierson of catinfo.org cannot stress highly enough how big an impact the drop in carb load can have on a cat's blood glucose numbers.) It was very early days and I still had a lot to learn and I was not yet sure of how to manage her insulin doses. Our vet at the time advised me to stick with the 3 unit dose she was on even though I was changing her food. I didn't think that was wise but I didn't trust my own judgment. Reluctantly I followed his recommendation. Thankfully I was home testing because that night Saoirse's blood glucose fell from a preshot of 310 down to 77 within three hours of the dose (measured on Alphatrak 2) - a drop of 233 points . You'll note that 77 is above the
nominal 'hypo threshold' of 68 for Alphatraks. Saoirse had a symptomatic hypo at the 77 -
ABOVE the nominal threshold! When I went to do her 'before bed' BG check I could wake her but she was not properly responsive. When I picked her up her body was limp and heavy. Had I not been home testing I might have just thought she was sleepy. Home testing saved her life that night (and I'm very grateful to the FDMB members who helped me that night).
I skipped insulin completely the next day and evening because I was scared and much too exhausted to be sure of staying awake to feed Saoirse through another low. I spoke to the vet during the day and he advised a drop down to 2 units for the following day. The preshot the following morning was 400 so I gave the 2 units per the vet's instructions. Five hours later Saoirse's blood glucose was at 113 - a drop of nearly 300 points!!! I was guided by the preshot (as advised by the vet) instead of the nadir - but I didn't know to the differ then. With harsh insulins you need to take both into account but ALWAYS the nadir should trump the preshot as a guide to dosing decisions.
For information, Saoirse went from 3 units BID to 1.0 IU AM / 0.5IU PM within 3 days of starting the diet transition (hence my advice to you to get a safe dose FIRST before even attempting to reduce the amount of carbs in Buzz and Woody's food).
After that second - even bigger - drop I made the decision to use Saoirse's data - specifically the nadir data - to guide my dosing decisions. I continued to discuss her dose with the vets for a little while but always, always, always the final decision on what dose to give was dictated by Saoirse's LOWEST blood glucose levels, and I gave less and less weight to the vet's input. It may be that I have given her less than was optimum at times but with this approach there is always tomorrow to refine her dose. I do seek opinions here from time to time but ultimately it is Saoirse's blood glucose data that 'calls the shots' in this house. This approach has served us very well and it has kept my beloved girl safe.
As I have advised in earlier posts, I'm not a vet but I do care passionately about the safety and well-being of every cat on this board. I try to use my own experience - good and bad - to shorten learning curves and also to save others from the difficulties I've encountered along the way. I hope I have been able to help you a little bit.
Mogs
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