I hardly ever post anymore, but feel compelled to do so in this case.
First off, your vet is dead wrong in saying there is a "100 point difference" between a human meter and a pet meter. I would ask them to provide research data that supports that claim. I am not aware of any that exists, but I'm not a vet.
For that matter, anyone who gives you a specific number to add or subtract from your reading across the entire range of blood glucose numbers is likewise wrong. The "old standard", and I have no idea where it came from was "30 points". I think it is just one of those things that got said so often by so many that it became a "standard" variance. But there is no real research to support 30 points either.
But what it comes down to is this - It doesn't matter what number someone gives you. 30, 50, 100, or whatever. It doesn't mean anything.
What are the numbers for? They are to let you know how well a dose of insulin is working in your cat. So you test before each shot, to make sure it is safe to do so. At first, we usually consider "200" to be the lowest number you would give a shot. But that isn't etched in stone either. A lot of it has to do with what your "normal dose" is, and more importantly, how much data you have at your disposal to make you feel comfortable giving insulin regardless of dose. Maybe you would reduce the dose if you weren't completely sure. Or skip altogether. The key is collecting data so that you can make those decisions on your own.
The thing to find out is "What is my vet going to do with the numbers?" If he's telling you to add 100 points, then he is going to base his advice on dose on higher numbers. That will likely cause him to advise a dose that is too high. Is he advising you to test in between shots to see what kind of numbers you get? Is he concerned with how low the BG goes 5-6 hours the shot when the insulin should be reaching peak effect? If not, then I wouldn't listen to a word he says regarding dose. You have to know the "low" to be sure the dose is not too high, and not too low. Many vets base Prozinc dose on nothing but the AMPS and PMPS test numbers. That is not a good way to base the dose on. You also have to know the low point.
One thing I am sure of after more than four years of reading and posting here is that anyone who gives you "dose advice" is going to err on the side of caution. Because the bottom line concern is the safety of your cat. None of us are vets. We might have a few vet techs around, not sure. But when people here give advice, they are going to be more conservative with your cat than they would be with their own cat. I personally was very aggressive with dosing when I had Bob, the Sugar Kitty. But I would never advise you to do the things I did with Bob. Because Bob was Bob, and he was right here in front of me. And if things went badly, I was here to intervene.
By the way, on the day Bob started insulin, I went to my vet to learn how to shoot, and to learn how to home test. She told me "Your Relion Micro is going to read about 30 points lower than my meter". I did test side by side with hers using the same drop of blood on two occasions. My meter was 30-35 points lower than hers. ON THOSE TWO TESTS. After a while, I began to feel that she was telling me to give Bob too much insulin (He got as much as 4 units of PZI if his BG was high enough. So without telling her, I started making all my own decisions on dose that were based on the numbers I got on my Relion meter. A few weeks later, Bob went into remission, and he lived another 2 and a half years without insulin. My vet was wrong too.
So take your Prime meter, test your kitty, and base your decisions on the data that you collect. Let your vet think what he wants. He isn't your kitty's caregiver. You are.
Carl