3/1 CRYSTAL AMPS 329 +7 279 + 10 306

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suki & crystal (GA)

suki & crystal (GA)

Member Since 2014
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Happy relaxing Sunday to all in LL

Haven't posted for a few days other than in the above condo which has been ongoing and contains some very good info for high dose kitties. Seems to be the general concensus is that Crystal needs aggressive Lev dosing with the occasional use of R. Last night I gave her a 5u increase, instead of my usual 3u. These high doses terrify me but it seems the only way to break through her resistance. She was pretty flat yesterday after a nice run of yellows and briefly dipped this afternoon at +7.

I'm thinking about trying another R trial this week, perhaps Thursday if anyone is around to watch over us? I don't mind doing the AM cycle which starts at 06.00 French time, or the PM cycle, whichever is most convenient. I'm a bit confused about when the Lev actually onsets, if experienced eyes could check her SS and give me some indication that would be really helpful. She seems to nadir roughly at about +7 in the AM cycle, although it's not by any means consistent, and a bit earlier in the PM cycle.

We are all shattered in Crystal's house, had houseguests arrive Friday/Saturday and although it was lovely to see old friends, it's also nice to return to normality, far too much eating and drinking! Kitties don't approve of having extra beans in the house disturbing their routine but Bolly the hound was in his element being totally spoilt and adored. Having spent the best part of the morning restoring order we are now having a quiet afternoon with lots of kittie cuddles and naps, beans included. Early night for all methinks.

Suki & Crystal
 
The nadir is simply the low point in a cycle - it can and does vary from cat to cat, and from one cycle to the next. The last few day cycles her nadirs have been between about +6 and +9.

I think you're asking about that in relation to using R mid-cycle, am I understanding correctly? The important part of using R post-nadir is just to see in that particular cycle that she's bottomed out and not going any lower. So if you want to use R mid-cycle, you would wait until you saw the beginning of a rise, or at least flat, and give the R at that point or later.

I can't help on Wednesday night or Thursday morning, my time - which is Thursday am/pm cycles your time. Might be able to do it next weekend but I'm not sure.

Company is wonderful, but it's oh so sweet when the house returns to normal. Enjoy your resting day!
 
Suki, your journey with Crystal and all the experience and wisdom pouring from people on this board is just simply beautiful. I am overwhelmed with your commitment to Crystal and with the village here at LL that's helping you both through. Know I cheer loudly from the sidelines.

Marilyn and Polly
 
Hi Julie, I was just reading, in a Sticky I think, about the importance of knowing one's kitty's onset, nadir and duration and I realised I couldn't discern when the onset was. Does this have any impact on the timing of giving the R dose? I suppose whilst I am learning, it might just be easier for me to stick to PS until I get more confident. Not to worry Julie about Thursday, I'm sure there will be someone available to watch over us.

Marilyn, thank you so much for your kind words of encouragement, you have no idea how much it means to me to have found such caring people who are more than happy to give their support and share their wealth of experience. I dread to think what would have happened to Crystal without the help of this Board. Please keep cheering us on!
P.S. I love reading about Miss Polly, what a character she is!

Suki and Crystal
 
Suki, Hope Crystal starts seeing some blues soon. It has taken Toby quite awhile to get in the good numbers. Just hope he keeps up the good work. I'm sure with the help of the kind
folks on LL you will be getting better numbers soon.
Hope you get some rest . Peg and Toby
 
Thanks Peg, I hope so too. All quiet here, everyone is asleep and there is a lot of snoring going on ... DH, dog, Crystal, and the 3 civvies are gently roasting on their blankets in front of the wood burner, domestic bliss!
 
Hello Suki - sounds like kitties are glad for the house to be back to normal today. I too don't want to think about what would have happened to Neko without this board. She'd probably still be on Caninsulin, and we'd both be miserable, if Neko was still here.:( Paws crossed the new approach busts through that nasty resistance for Crystal.

Crystal's onset is a tricky one to figure out, because she's so flat. You have to look at cycles where she's not bouncing and spot where she does show some movement. My guess is somewhere around +4 is where she starts to go down. You might want to do a few cycles with tests at +3 and +4. If you don't see any movement there, try a +5. FWIW, Neko's Lev onset is around +5. Toby looks like he's around +3. As long as Neko is high, I don't bother getting a second test in the cycle until after onset. As for nadir, I've noticed Neko's on Lev to be anywhere from +5 to +15 with most commonly between +9 and +12, though last night it was later. IAA cats are notorious for having variable nadirs.:rolleyes:
 
Hi Wendy, thanks for popping in and answering my query. They certainly don't make it easy for us. I'll give it a go with the +3 and +4 testing as you suggest to see if I can spot the onset.
 
Hi there :coffee::coffee::coffee::cool:

Grayson & Lu said:
See what the increase gives you, and let it settle in for a couple of days. The first few cycles/days, you'll still be filling the shed, so it may be 3-4 days before you start to see a response. Don't be disappointed if there's not much immediate response.
Click to expand...
I agree that the larger increases may need longer than 4 cycles to settle in. Since this is the first 5u increase, how about giving it at least 6 cycles (3 days), possibly 8 cycles (4 days) before the next increase?
suki & crystal said:
I'm a bit confused about when the Lev actually onsets,
Click to expand...
Onset ( the length of time before insulin reaches the bloodstream & begins lowering blood glucose) for Lev is around +4-ish, however it can vary (ECID). It can be difficult to pinpoint when many cycles are flat or wonky from dose changes. If IAA is on the scene that can further blur the picture. :rolleyes: Holding the dose for more than 4 cycles may result in a cycle or 2 that are more revealing of when the onset is.
suki & crystal said:
Does this have any impact on the timing of giving the R dose?
Click to expand...
Yes, depending on when the R peaks relative to onset. The most advantageous scenario is for the R to have peaked at the point where L has reached the bloodstream and is ready to begin it's 'work-shift'
suki & crystal said:
I suppose whilst I am learning, it might just be easier for me to stick to PS until I get more confident.
Click to expand...
I agree. You are still in the process of discovery with R.
Be patient and methodical. With this journey all data is good data.
suki & crystal said:
These high doses terrify me but it seems the only way to break through her resistance.
Click to expand...
Having seen the power of R with other kitties, now, with BK having spent 5+ years at the falls, when I look at all the R I shot into BK it often makes me weak in the knees - seriously.

I can keep an eye on you and Crystal for her PM cycle on Thursday. To confirm-
Thursday 03/05
18:00 Paris / 12:00 Baltimore
correct?
 
That's great Sandy, thank you for volunteering to watch over us on Thursday, times are correct. I take your point about holding the larger dose for a few more cycles and will stay at 6 and see what happens. Just going to do a before bed test, then I'm off to bed, I really can't keep my eyes open any longer. See you Thursday!
 
Good luck with the higher increase, Suki! The high doses scared me too, but you're keeping a close eye on Crystal so she's in good hands. Keep up the great work. I'll check in on you later this week too!
 
Please refresh my memory... did you say that Crystal has a bad tooth?

In a recent conversation, I remembered that Grayson's persistent staph infection in his ear was probably part of the reason that his numbers were so flat. It's hard to say for sure, as we reached his max dose, cleared the ear infection, and experienced the "onset" of his SRT treatment all about the same time. A "perfect storm" of improvements... but I know the infection was a factor to be noted.
 
@Suzanne & Cobb(GA) @Grayson & Lu thanks for looking in earlier. No problem (that I know of) with Crystal's teeth but she is not very cooperative with me poking about in her mouth. Also her gums are quite enlarged with the acro.

I'm just about to do a new post for Monday but thought you might like to be the first to share our good news - first ever blue number at PS (175)!!!!!!!! I am just totally gobsmacked, I nearly had heart failure! I'm just too excited to go back to bed. I even tested her 10 minutes after just to make sure I wasn't dreaming and got 183. Anyway, just off to do my new post, hope the blues continue throughout the day.


Suki and Crystal
 
I did the same at the first blue. Thought OMG, I need to cut back. But really I didn't. You have to re-train yourself to the new numbers... a new normal! Congrats!!!
 
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