Just to complicate things, cats can have urinary infections without demonstrating inappropriate urination. Cats at higher risk of UTIs (female cats, diabetic cats, CRF cats, etc.) should always be sure to have a urinalysis +/- urine culture as part of a regular checkup. My cat Earl had diabetes, kidney disease, and was on pred so I did a culture every 4-6 months for him.
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Vet Microbiol. 2009 Apr 14;136(1-2):130-4. Epub 2008 Oct 28.
Occult bacterial lower urinary tract infections in cats-urinalysis and culture findings.
Litster A, Moss S, Platell J, Trott DJ.
The School of Veterinary Science, The University of Queensland, Brisbane, Australia.
catvet@purdue.edu
Abstract
Bacterial urinary tract infections (UTIs) can be detected in feline urine submitted for urinalysis and culture as part of the diagnostic workup for a variety of conditions. Our aim was to investigate urinalysis and culture findings in urine specimens from cats with no history of lower urinary tract signs. Study inclusion criteria required cystocentesis specimens from cats with no history of lower urinary tract signs, inappropriate urination, or previous UTI (including pyelonephritis). Of 132 specimens, 38 were culture positive and 94 were culture negative. Culture positive urine specimens were more likely to come from older female cats (p=0.03, p<0.001, respectively) and they had higher pH (p=0.001), erythrocyte (p=0.013) and leukocyte counts (p=0.003) than culture negative urine specimens. Gram-negative infected specimens (n=15) had lower urine specific gravity and higher leukocyte counts than Gram-positive infected specimens (n=21; p=0.0012, p=0.005, respectively) and culture negative specimens (p=0.003, p<0.0001, respectively). Urine protein:creatinine ratio was higher in Gram-negative infected urine than in culture negative urine (p=0.013). Enterococcus faecalis was the most commonly isolated bacteria (19 of a total of 44 isolates; 43.2%) and E. coli phylogenetic group B2 was the most common Gram-negative isolate (14 of a total of 44 isolates; 31.8%). We conclude that feline bacterial urinary tract infections can occur in cats without lower urinary tract signs, particularly older females and that they are associated with high urine erythrocyte and leukocyte counts.
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J Feline Med Surg. 2007 Apr;9(2):124-32. Epub 2006 Nov 7.
Urinary tract infections in cats with hyperthyroidism, diabetes mellitus and chronic kidney disease.
Mayer-Roenne B, Goldstein RE, Erb HN.
Cornell University Hospital for Animals, College of Veterinary Medicine, Cornell University, Ithaca 14853, New York, USA.
Abstract
The prevalence of urinary tract infections (UTIs) in cats with hyperthyroidism (n=90), diabetes mellitus (DM) (n=57) and chronic kidney disease (CKD) (n=77) was evaluated retrospectively. It was found to be 12% in cats with hyperthyroidism and DM, respectively, and 22% in cats with CKD. Associations between UTIs and clinical signs, biochemical markers in serum and urinalyses were investigated. Many of the cats with UTIs had no clinical signs of lower urinary tract disease or changes in their laboratory values indicative of infection. Therefore, a urinalysis alone should not be used to exclude UTIs in these cats. UTIs are relatively common in cats with hyperthyroidism, DM and CKD, and urine cultures are recommended as part of the basic diagnostic plan for cats suspected of suffering from these conditions.