I am happy to report that I switched our Cooper cat from the harsh Humilin N to Lantus and I am seeing an improvement. He went from being almost unresponsive and headed downhill with frequent vomiting to bright and perky and little vomiting or dry heaving. We are however still concerned as he has no appetite so I still have to force feed him the A.D. twice a day. The vet also did a full blood panel and found his biliruben count to be high so this is definitely an issue. With the proper nutrition and the stabilization of his bg, we know the liver function can improve but we are still very concerned at his lack of interest in food and the dry heaving/vomiting. Any advice or suggestions for this? Also regarding Lantus I am reading that if it is properly stored it can be used for longer than the recommended 28 days. Saw some posts on this board about that but was wondering if anyone has any personal experience? TIA! :smile: