Shaikha - went to vet, has a fever

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wombat88

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She would not eat again last night and felt pretty warm. She's got a fever and was still running one this AM, so we are leaving for the vet now. Will let you know as soon as i know something. Thankfully her glucose still isn't in the stratosphere, but it definitely has spiked as well (372 at +5). I was surprised it wasn't high last night, but I guess it caught up.
 
Re: Shaikha - going to vet, has a fever

Thinking of you both. Not eating makes me nervous. nailbite_smile
 
Re: Shaikha - back from vet, has a fever

We're back from the vet. She does have a fever but other than a very full bladder (which emptied just fine), her abdomen feels good. She's tender in the area of her pancreas, but okay with being handled other than that. He found no fluid or evidence of masses. My vet feels acute pancreatitis that is the root cause of this, as her kidney function tests were okay (just slightly elevated, not different than previously) and her urine looks clear so it is unlikely a UTI is to blame. Liver function tests look good too. The one very odd reading was a lipase value over 6000 (normal is 100 - 1400; so she's over 4 times normal levels). Though blood levels of lipase are not specifically diagnostic for pancreatitis, since her kidney values were not that bad most likely pancreatitis is the cause. He put her on antibiotics and I'm to continue giving fluids, buprenorphine, etc. for the next day or two. If she's not improving or if her temp gets worse, I'm to bring her back in. We are hoping that her appetite will pick up with more vigorous bupe thearpy and continued supportive care, including the antibiotics. We can repeat her spec fPL test but that requires a fast, so we could not do one today. My guess is though it will be in the stratosphere.

She seems weak and lethargic and has little appetite. I assist fed her with syringes this AM and she's kept it it down. Will continue to offer food but if she won't eat, I'll have to assist feed. She's down to 7.2 pounds vs. her normal 8 pounds, so I need to get food into her. She won't even nibble on dry food, so you know she's sick! I'm trying the blended food trick I used with my GA Tabriz. If she won't lap it up, it is easy to put in syringes and get down that way.

No ketones, so no worries there, but I'll continue to test her daily. I'm oping we can get the fever under control quickly. If it won't come down, then we'll need to dig further and likely get her on IVs and stronger ABs. She's spiked fevers before in bad acute attacks, so this would not be unusual in that regard. My guess is if we do the spec fPL it will be very high given how she's feeling. I was reading another article that talked about using plasma transfusions to provide clotting factors I plan to share with my vet as she's still bleeding odd. Apparently with some of these cats, disseminated intravascular coagulation can occur which may explain what I'm seeing (http://www.marvistavet.com/html/body_pancreatitis__feline_.html). I don't know if he's able to do something that sophisticated or not. Her PCV is 18-19%, so it is a little lower but is likely just the pancreatitis that is causing that drop.

Am off to get a nap. I hardly slept at all last night and found a million typos already in what I'd posted. I think I found them all, but if some remain I'll blame it on sleep deprivation.

Glucose is high, but not off the charts. My vet said just to adjust dose based on how she's doing, since the fever will mess with her levels. I know what to do, but hope we can stay ahead of this -- and that she responds to the ABs quickly.
 
Re: Shaikha - going to vet, has a fever

Hi Wendy, well it doesn't sound too bad .... did he do an ultrasound to check for fluid and masses? If she's having a flare-up but no fluid, that is good. She is so small! Payne is almost two of her. You sound on top of all of it, you are a good Mama bean! Give her a big hug from us!
 
Re: Shaikha - going to vet, has a fever

Hey Wendy---I agree with Nancy, it doesn't sound to bad. Hopefully it is just a flare up and she will feel better soon. Keep us updated!
 
Re: Shaikha - going to vet, has a fever

Hi Wendy,

I was just dropping in to check in on my PZI beans & kits. I'm so sorry to see that Shaihka is having another pancreatitis attack! Seems like your two just can't catch a break. I wholeheartedly recommend the fresh frozen plasma transfusion if you and your vet can arrange one. It turned the tide for my Harley who I do believe had subclinical DIC. (It was suggested by a fellow member that possibly use of the Anzemet could have caused Harley's PTT time to skyrocket to over 400. But so far the 3 vets that I have asked said no, that wasn't likely. Plus I've used the Anzemet with him daily since mid-May and we've kept tabs on his coagulation by running a full panel, and Harley has not experienced a re-occurrence of increased PTT. All the rest of his coagulation values are also normal. So I don't think the Anzemet was the culprit.) If your vet can't order the frozen plasma and administer it himself, is there an ER where you could take her for that procedure?

When Harley was admitted to the ER, I was told that cats are either blood types A, B, or very rarely AB and most domestic shorthair or domestic shorthair mixes are type A. Fortunately Harley was type A. As I recall, it took 3-4 hours to thaw and warm the plasma and then the transfusion itself took about an hour and a half. The plasma is infused slowly and the kitty should be monitored for evidence of transfusion reactions. e.g. rejection. Here's a really cool article on feline blood types. As Shaihka is a doll-faced Persian I wonder if she's possibly a type B?

Feline Blood Groups

Wishing you both rest and healing! cat_pet_icon :YMHUG:
 
Re: Shaikha - going to vet, has a fever

Laura and Harley said:
Hi Wendy, I was just dropping in to check in on my PZI beans & kits. I'm so sorry to see that Shaihka is having another pancreatitis attack! Seems like your two just can't catch a break. I wholeheartedly recommend the fresh frozen plasma transfusion if you and your vet can arrange one. It turned the tide for my Harley who I do believe had subclinical DIC. (It was suggested by a fellow member that possibly use of the Anzemet could have caused Harley's PTT time to skyrocket to over 400. But so far the 3 vets that I have asked said no, that wasn't likely. Plus I've used the Anzemet with him daily since mid-May and we've kept tabs on his coagulation by running a full panel, and Harley has not experienced a re-occurrence of increased PTT. All the rest of his coagulation values are also normal. So I don't think the Anzemet was the culprit.) If your vet can't order the frozen plasma and administer it himself, is there an ER where you could take her for that procedure?

When Harley was admitted to the ER, I was told that cats are either blood types A, B, or very rarely AB and most domestic shorthair or domestic shorthair mixes are type A. Fortunately Harley was type A. As I recall, it took 3-4 hours to thaw and warm the plasma and then the transfusion itself took about an hour and a half. The plasma is infused slowly and the kitty should be monitored for evidence of transfusion reactions. e.g. rejection. Here's a really cool article on feline blood types. As Shaihka is a doll-faced Persian I wonder if she's possibly a type B? Feline Blood Groups Wishing you both rest and healing! cat_pet_icon :YMHUG:

Thank you so much for checking in, Laura! We live in a rural area, so while my vet is pretty clued in and has more equipment than most, an ultrasound isn't one of them. We've suspected a blood clotting issue with her for a while now. She's got virtually no platelets in her system, but we presumed that was due to treatment with leukeran (caused severe anemia that has never fully resolved), though she's always had low white cell counts (clear for the usual culprits, like FIV, FIP, etc). But lately she's been bleeding unusually long when I do subQ fluids or even sticks to get glucose and she shows evidence of bleeding under the skin at times near stick marks. Her blood is more like colored water and just does not act normally, and runs easily. She's got anemia as well, but it appears to be due to chronic disease based on serum ferritin tests. Her red counts did increase some as she got over the leukeran but they have never really gone into normal territory and have hovered in the 17% - 20% range.

There is an ER about 1.5 hours from me (like I said, rural) but to be honest I'm not that confident in their capability having used them previously. I unfortunately know a lot about blood transfusions as does my vet, since my GA Tabriz had severe anemia caused by chronic renal failure and then development of epogen antibodies. I just had a talk with my vet who knows about doing plasma transfusions, but he wanted to do some more research before we go that route. If he can't get plasma, we could easily do whole blood as Tabriz had transfusions frequently (over 26 in all!). Persians and cats from overseas can be Type B, but both Tabriz and my Siamese-Persian mix (one of Tabriz's donors) tested as Type A. I'm not sure we've typed Shaikha but my vet knows the procedures well. I actually trust him more for transfusions than the ER vet, who did the first one on Tabriz and never even typed! Yikes.

Her PCV is low enough that even a whole blood transfusion would not hurt. Plasma sounds even more promising though given Harley's experience. I do think we've got a problem here and treatment may correct several things at once. Wish we had an internal medicine facility near by. There are places that are set up to take care of bad accidents, etc. but not the type of specialists you'd see in larger cities. We were going to run a coagulation panel previously but it got left off the list. We'd run a laundry list of blood tests and had to repeat them because the lab ended up mixing up results with another cat. As low as her PCV was at the time we were afraid to take more so we let it slide. It seemed to get better so I didn't think to repeat it, but the bleeding has gotten worse since this flareup so I do think the two are tied together with her overall condition.
 
As I've said before she sure is lucky to have you to take care of her. I woudn't have a clue! I'm sorry she's having a rough time right now but if anyone can deal with it it's you!
 
I'm so glad the vet visit went well and there is nothing more serious going on. You already know how to handle this.

Prayers and vines to you both.
 
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