Reduced appetite, possible respiratory problems

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KM-JB-127

Member Since 2022
Hello, this is my first post here. I am appreciative of any feedback or advice that can be offered. I recognize that the responses should not be treated as formal medical recommendations or diagnoses.

Our cat Lilly is 12.5 years old, female, indoor tabby. Normal weight approx. 12 lbs.

In September 2018, at age 9, she was diagnosed with diabetes. Prior to that, she ate dry kibbles and grazed, and eventually became overweight. After her diagnosis, we switched her to Purina DM wet food and dry food, and Lantus Glargine insulin, per vet recommendation.

After several followup vet visits and curves, we decided on 2 units at breakfast and 1 unit at supper, 12 hours apart, per vet recommendation. We rigidly stuck with this for a long time afterwards and she seemed very healthy; she would eagerly eat and receive her insulin every 12 hours, and she was at a healthy weight and not showing any signs of any health issues. Vet visits became less frequent in 2020-2021 due to COVID but Lilly still seemed fine so we stayed the course.

In August 2021, we took her for a routine checkup and did a full blood panel; all results were good, except her blood sugar was high (around 20), so we started gradually increasing her insulin intake and doing more curves. Eventually we increased her supper dose to 2 units, so she was now getting 2 units every 12 hours. We also learned how to check her blood sugar at home and how to do at-home curves. Overall, her blood sugar improved, but results were inconsistent; at her lowest (6 hours post meal + insulin), she would typically range from 7-14, despite her routine being very rigid.

Meanwhile, she still seemed totally normal; however, she gradually started being more finicky with the Purina DM wet food. Sometimes she would not eat the wet food until we coaxed her, or until we sprinkled the dry food on top of it. Ultimately we never had trouble getting her to finish it; we generally only had trouble with her starting it. The vet said she had some gum inflammation/gingivitis, and that the cold wet food (when refrigerated) may be sensitive, so we tried warming it up in the microwave, and that seemed to help. We planned on possibly getting surgery to fix her gums but we wanted to try to get her sugars stabilized first.

Fast forward to February 2022. Approx. 2 weeks ago she stopped eating, for seemingly no reason at all. Whatever she did eat, she would vomit; fortunately, the vomiting ultimately only lasted a few days and is no longer an issue. She still drank water regularly and continues to do so. We tried different types of wet foods (and even some treats) to entice her to eat, but we didn’t have much success. We took her to the vet (note - a different vet than our usual one, because we wanted her seen ASAP and our vet was not available on short notice), and the vet did a full blood panel, urinalysis, x-ray scans, and physical exam, and found no issues except mild/moderate constipation. The vet noted the gum issues but did not seem as concerned as our regular vet. The vet’s theory was that the constipation was interfering with Lilly’s appetite and digestion. She gave Lilly an enema, Restoralax, and buprinorphine. After a few days, Lilly resumed having regular, healthy bowel movements, and constipation no longer seems to be an issue.

Meanwhile, Lilly’s appetite is still poor. She will act hungry but will then only have a few bites of food before trying to cover it and walk away. Generally, she is more interested in dry food than wet food. We have tried multiple types of wet food - including Hill’s “urgent care” and “recovery” per vet recommendation - but they have little impact on her appetite.

She has also had bouts of frequent sneezing during this period; this is highly unusual for her. We see some mild discharge from her nose, clear in colour, but no other symptoms. She has some discharge in her eyes, but it’s brown in colour, which the vet said is normal. Of note, sometimes in the past when begging for food, she would cough; we thought maybe she was “faking it” to try to get attention, as it never seemed to be a real problem and she only did it when begging for food. Now, in hindsight, we wonder if she has chronic respiratory problems.

We took her back to the same vet, who agreed that a respiratory infection could be impacting her ability to smell and taste her food. She said respiratory infections are usually viral, but gave Lilly a general antibiotic just in case. The vet also gave Lilly an appetite stimulant. If she does have a respiratory infection, we have no idea where she got it; she’s an indoor cat and we have no other pets.

Now, approx. 2 weeks since this all started, the constipation seems to be gone and Lilly is not really sneezing anymore, but she still has a poor appetite and will not eat much. As a result, she has not had insulin throughout all of this, but we check her sugars sporadically and she’s remaining around 14. What’s most frustrating is she seems totally fine otherwise, but is visibly getting skinnier and weaker due to not eating much, and we are struggling to get her back into any kind of schedule to regulate her blood sugar. In an attempt to at least sustain her, we are leaving the dry food out and allowing her to graze when she’s hungry; we recognize this is not good for constipation, dehydration, and blood sugar, but we are trying to at least sustain her while we try to figure out what is going on.

Sorry for the long post. Thanks for reading this far. Any help you can provide is greatly appreciated. We do plan to follow up with the vet again, but are looking for any additional insights in the meantime.
 
Did her appetite improve the the appetite stimulant?

A couple of observations may help. All of the dry foods you've been feeding Lilly are high in carbohydrates. In all likelihood, the higher blood glucose (BG) values aren't able to respond to insulin because you're in essence feeding your diabetic cat cookies and the insulin can't offset the effect of a high carbohydrate diet. Regardless of what the pet food manufacturers lead you (or your vet) to believe, the prescription dry foods are very high in carbs. In addition, the quality of the prescription foods is poor. Most cats tire of the food which may be contribute to your cat not wanting to eat.

If there is some sort of respiratory issue, one thing I found that is helpful is to run the shower and get your bathroom steamy. Then, steam your cat! Well, don't really steam her but the steam in the bathroom may help to break up whatever is making it harder for her to breathe/smell. Either microwaving her food or adding warm water or anything smelly (e.g., some tuna) may help.

We also approach dosing a bit differently than your vet. Lantus does better with consistency. The dose should be the same in the AM and PM. You may want to take a look at the sticky notes at the top of the Lantus board.
 
Did her appetite improve the the appetite stimulant?

A couple of observations may help. All of the dry foods you've been feeding Lilly are high in carbohydrates. In all likelihood, the higher blood glucose (BG) values aren't able to respond to insulin because you're in essence feeding your diabetic cat cookies and the insulin can't offset the effect of a high carbohydrate diet. Regardless of what the pet food manufacturers lead you (or your vet) to believe, the prescription dry foods are very high in carbs. In addition, the quality of the prescription foods is poor. Most cats tire of the food which may be contribute to your cat not wanting to eat.

If there is some sort of respiratory issue, one thing I found that is helpful is to run the shower and get your bathroom steamy. Then, steam your cat! Well, don't really steam her but the steam in the bathroom may help to break up whatever is making it harder for her to breathe/smell. Either microwaving her food or adding warm water or anything smelly (e.g., some tuna) may help.

We also approach dosing a bit differently than your vet. Lantus does better with consistency. The dose should be the same in the AM and PM. You may want to take a look at the sticky notes at the top of the Lantus board.

Thank you for the reply. The appetite stimulant was mildly effective but ultimately did not change much for us. We were given one 15 mg tab of mirtazapine, broken up into four pieces, which we gave to her every 48 hours per vet recommendation.

To clarify - the Purina DM is high carb? Even though it is specified as low carb and meant to help manage diabetes? Forgive my ignorance here, as this food was prescribed by our vet so we assumed it was fine.

What alternative foods would you recommend?

Thank you
 
All of the prescription "diabetic" dry foods are quite high in carbs. The DM canned food is about 7% (don't quote me -- that's from memory) which is acceptable but most cats end up refusing it after a while. I had a very food motivated diabetic cat and she refused to eat DM. It's a very poor quality food. You want to look for something other than animal by-products as the primary source of protein. Muscle meat is preferable to by-products.

FWIW, there was a class action suit against the manufacturers for calling their various food "prescription." There's nothing prescriptive about the food -- it was a marketing ploy to get people to pay more for the "prescription" foods. Compare DM to a human grade food such as Tiki Cat, Ziwi Peak, or Weruva. They cost about as much as DM but the quality is vastly better.
 
@KM-JB-127 do you check for Ketones with with a blood ketone meter or the whole "catch urine in a ladle and dip ketostix" method? When I hear of a kitty turning their nose up at a food they normally enjoy ketones immediately come to mind.
 
Here is a link helping us to help you link. If you noticed, our members have some basic information about their cat's in their signature. This helps us to not pester you by asking the same questions (your cat's name, insulin type, date of diagnosis, etc.) repeatedly. We also have a link to our spreadsheet in our signature. We are very numbers driven. The spreadsheet is a record of your cat's progress. By linking it in your signature, we can follow along and provide feedback should you need the help.
 
Using a humidifier in the room Lilly spends the most time in can help also. I have also found that adding L-lysine to food also helps with respiratory system issues. it helps with strengthening the immune system. Another product that I use with Duquessa is HomeoPet Nose Relief. She has chronic sinus issues and this helps a lot in keeping it under control. you just add a few drops to the food each day. I found it at Petco but I think other pet stores may also carry it.

If she is not eating you should at least syringe feed her. Going without food can cause other health issues including fatty liver disease.
 
True coughing (not to be confused with the “hacking” they do when trying to being up a hair ball) is relatively rare in cats and can be a sign of certain medical issues. Is she still doing that? I’d definitely mention it to the vet.

Acting hungry but taking a few bites and walking away can be a sign of nausea. Anti-nausea meds so I as ondansetron can be helpful. An appetite stimulant given to a nauseated cat can be useless, even counterproductive.

What exact tests were run? If you have results of blood work, you can post them here; there might provide additional clues. If not, you can contact your vet and ask for a copy.

I have more thoughts but will wait for answers to those questions first.
 
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