Possibly 2X Ursodiol dose anyone know anything about it?

Status
Not open for further replies.
Melanie and Smokey

Melanie and Smokey

Very Active Member
I might have given Smokey a little over twice her dose of Ursodiol. Does anyone know enough about this med to know if this is this a monitoring situation or an ER trip situation?

We have Smokey on a boatload of meds right now for treating triaditis. We are experimenting with different forms of the meds because she does not medicate well, especially with needing to get meds 4 times a day. When she wouldn't take the capsule with the Ursodiol and Metronidazole this morning so I pulled out the liquids and gave her that. I am wondering if I might have drawn from the Ursodiol bottle twice. I wouldn't even be thinking I did because the syringes are rubber banded to the bottle and I usually don't even set them down after pulling off the syringe, but she freaks from the Metron - running, drooling, hiding, sometimes vomiting - this time she had such a non-reaction, just ran a few feet away from me and scratched at her cheek a bit, then glared at me that my first thought was, oh god did I just give her the Ursodiol twice?

Its been about a half hour and nothing seems off. The young boy kitten seems intent on pissing her off so she is constantly moving around to get away from him. She's eaten a bit. I saw her staring in the water foutain, but didn't see her actually drink. My vet is closed and the pharmacy that sold it to me is closed, though they couldn't tell me anything about it when I picked it up so I doubt they'd be able to tell be anything about overdose issues. hate to have the ER vets get it out of her unless there is danger because it takes enough work to gets these meds into her!

Any thoughts?

eta: her dose is 50mg once a day which is suspended to be drawn in .5ml, if I did draw it instead of the Metron, I drew another .55ml so she would have gotten another 55mg. She is around 11 pounds right now.
 
I added that to my first post while you were asking :)

her dose is 50mg once a day which is suspended to be drawn in .5ml, if I did draw it instead of the Metron, I drew another .55ml so she would have gotten another 55mg. She is around 11 pounds right now.

From looking around, if I did give 105, its a bit over what she should get, normal dosing is 5-15mg/kg which would be 25-75 I think.
 
She should be okay.....may do some vomiting or have diarrhea though. Hope and Mishka get ursodiol and it was increased to a 1 1/2 dose, compounded in capsule from compounding pharmacy here in MI.
 
Thank you!

She seems like she is OK, laying under the cat cabana next to me here taking a bath. I did call the ER because when hubby came home she hid under the bed and he said she was acting weird and crying a lot more than normal when he tried to get her out (of course she did, he had 4 of our nephews with him, she didn't want to come out!). The ER was really busy so they were willing to give answers over the phone instead of the usual - bring the cat in - the tech said she should be ok unless she gets diarrhea so bad that that makes her sick. She said in some acute cases the dosage would get above what I gave Smokey and in one case she saw a 7 lb cat getting 50mg every 4 hrs, YIKES!, that poor kitty's tummy must have felt aweful.
 
Double dose probably not a problem. It only encourages bile flow, and breakdown of stones if any exist. Could cause minor pain, but not long lasting.
It has a pretty broad dosing range.
 
I am currently treating my 5 yr old male cat for Fatty Liver (hepatic Lipidosis) and is on the Metron-blah smells NASTY and is also on Ursodiol, along with 4 other meds. One morning, half asleep still, i mistakened his Ursodiol for the Metron. one. His Ursodiol dose is .25ml and Metron. is .8 ml. After i gave him his .25 of Ursodiol, I ACCIDENTALLY gave him another .8ml of it. I was very worried as i had to go to work. I checked on him at lunch and he was fine. It was weeks ago, and he is still OK.
 
If she finds pill pockets agreeable, it is possible to get metronidazole as tablets, cut them into quarters, and put a quarter tablet into part or all of a pill pocket.

Spitzer is taking his that way and it is so much easier than doing a compounded liquid! The quarter tablets of metronidazole are chunky enough that they could be cut a bit more and wrapped in separate pieces of pill pocket. I actually use half of a pocket per dose I'm giving. Extra splitting of the piece to be dosed helps ensure it doesn't stick in the throat or get tasted, as does dosing prior to feeding.
 
This post is actually from last July.

And, no Smokey won't take pill pockets anymore. Eats whatever we stick the pill in and spits the pill back out on the floor. She just won't take pills any way shape or form anymore. But we stopped giving her the metronidazole a while back because her numbers came down and it was just to stressful for her to take it
 
Status
Not open for further replies.
Back
Top