Pacreatitis

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ShannonO'C

Member Since 2014
Our boy has been off insulin for three days but has had another flare up of pancreatitis. He had an appetite stimulant yesterday and ate everything in site, but today he is lethargic and not eating today. He is drinking well. We have given him half dose of pain killers because he was very disorientated with a full dose. Do you think we should give him a full dose. He's also using a heating pad.
 
First, HUGS - pancreatitis is hard. You may need to syringe feed him to get some food in him - he needs food for his body to fight this. How are his numbers since he's off insulin?

Unfortunately I can't help with your painkiller question. How about adding 'Painkiller Question' to your title to get more eyes that CAN answer. To add to your title, find the 'Thread Tools' on the right above your original post. Click on it, you'll see 'Edit' in the dropdown.

Another HUG,
 
Hi Shannon,

Firstly, I'd recommend in the strongest terms to keep on top of the inappetence your cat is experiencing. First up, I'd suggest taking a good note of his clinical signs - particularly signs of tense posture, meatloafing and any signs of nausea (symptom checker here) such as crouching with head lowered. Hiding is another common behaviour that may be indicative of the presence of pain. Those are some general signs, but your boy may have specific 'tells' for when he's in pain. I'd also speak to the vet about getting a supply of anti-nausea meds (e.g. ondansetron). I found that Saoirse needed support for quite a while from both the appy stimulant (cyproheptadine in her case) and the anti-nausea med (ondansetron) to help her eat. Are you giving your boy cyproheptadine or mirtazapine for appetite? If it's cyproheptadine (antihistamine) and the painkiller is buprenorphine (opiate), then the combination of the two could be making your cat more drowsy/lethargic. That was certainly my experience with Saoirse, What dose of appy stimulant are you giving, and what's the dosing frequency? If it's cyproheptadine maybe ask your vet about adjusting the dose? Saoirse weighs about 9½lbs and a dose of 1/8 of a 4mg tablet was enough to get her eating for anywhere from 8-24 hours with minimal drowsiness that wore off fairly quickly. Saoirse only ever got one dose of mirtazapine - I stopped it when I learned more about its side effect profile after she became mildly psychotic after taking it (it can induce serotonin syndrome). If that's the appy stimulant you're using it might be worth speaking to your vet about possible drug interactions (possibly do some research online, too?).

Hope that helps a bit with what to ask your vet about re the meds. BTW, Saoirse's very med-sensitive. All but the smallest of bupe doses makes her very dopey, too.

WRT worsening of pancreatitis symptoms after cessation of insulin treatment, I've had this problem and so has Lisa, Tisha's mom. Saoirse was almost asymptomatic for pancreatitis at the time her Caninsulin treatment had to stop (for safety reasons - dropping her too low but still not fully regulated). In less than 72 hours she was really inappetent and just got worse and worse. Thanks to the advice I got here about treatment and feeding I was able to get the right meds from our vets and she also started treament with Lantus. To address eating problems she had her cypro and ondansetron, the anti-nausea med being needed for much longer than the appy stimulant. Second time around I weaned Saoirse very gradually off Lantus. She still experienced a marked increase in nausea symptoms a day or so after the insulin treatment ended, and also her appetite lessened. I managed to treat her symptoms with ondansetron only and a lot of coaxing for the inappetence. It has taken a few weeks to restabilize her but thankfully she was only uncomfortable this time round, not seriously ill. She is eating very well now and only needs an occasional dose of ondansetron. She also seems to find it helpful and soothing to lick a toy containing organic catnip leaves a help when she has a bit of discomfort after a meal. (Catnip is professed to have properties that aid digestion and may provide mild analgesia).

Another forum kitty called Tisha has been through similar. Her pancreatitis symptoms flared up really badly, she experienced severe inappetence and became very ill after one attempt to take her OTJ. Similar to Saoirse, she got the necessary treatments for the pancreatitis and resumed insulin therapy. A subsequent attempt to take Tisha OTJ also resulted in worsening of pancreatitis symptoms. I'm not sure how Tisha got on after that (I was moving house). Lisa is her caregiver - member name is Tisha's_Person - if she doesn't see this thread, it might be an idea to drop her a PM to see if she can maybe share some of Tisha's experiences with you.

Please let us know how you both get on. As Lyresa recommends above, keep an eye on his BG numbers.
 
Hi Shannon,

Firstly, I'd recommend in the strongest terms to keep on top of the inappetence your cat is experiencing. First up, I'd suggest taking a good note of his clinical signs - particularly signs of tense posture, meatloafing and any signs of nausea (symptom checker here) such as crouching with head lowered. Hiding is another common behaviour that may be indicative of the presence of pain. Those are some general signs, but your boy may have specific 'tells' for when he's in pain. I'd also speak to the vet about getting a supply of anti-nausea meds (e.g. ondansetron). I found that Saoirse needed support for quite a while from both the appy stimulant (cyproheptadine in her case) and the anti-nausea med (ondansetron) to help her eat. Are you giving your boy cyproheptadine or mirtazapine for appetite? If it's cyproheptadine (antihistamine) and the painkiller is buprenorphine (opiate), then the combination of the two could be making your cat more drowsy/lethargic. That was certainly my experience with Saoirse, What dose of appy stimulant are you giving, and what's the dosing frequency? If it's cyproheptadine maybe ask your vet about adjusting the dose? Saoirse weighs about 9½lbs and a dose of 1/8 of a 4mg tablet was enough to get her eating for anywhere from 8-24 hours with minimal drowsiness that wore off fairly quickly. Saoirse only ever got one dose of mirtazapine - I stopped it when I learned more about its side effect profile after she became mildly psychotic after taking it (it can induce serotonin syndrome). If that's the appy stimulant you're using it might be worth speaking to your vet about possible drug interactions (possibly do some research online, too?).

Hope that helps a bit with what to ask your vet about re the meds. BTW, Saoirse's very med-sensitive. All but the smallest of bupe doses makes her very dopey, too.

WRT worsening of pancreatitis symptoms after cessation of insulin treatment, I've had this problem and so has Lisa, Tisha's mom. Saoirse was almost asymptomatic for pancreatitis at the time her Caninsulin treatment had to stop (for safety reasons - dropping her too low but still not fully regulated). In less than 72 hours she was really inappetent and just got worse and worse. Thanks to the advice I got here about treatment and feeding I was able to get the right meds from our vets and she also started treament with Lantus. To address eating problems she had her cypro and ondansetron, the anti-nausea med being needed for much longer than the appy stimulant. Second time around I weaned Saoirse very gradually off Lantus. She still experienced a marked increase in nausea symptoms a day or so after the insulin treatment ended, and also her appetite lessened. I managed to treat her symptoms with ondansetron only and a lot of coaxing for the inappetence. It has taken a few weeks to restabilize her but thankfully she was only uncomfortable this time round, not seriously ill. She is eating very well now and only needs an occasional dose of ondansetron. She also seems to find it helpful and soothing to lick a toy containing organic catnip leaves a help when she has a bit of discomfort after a meal. (Catnip is professed to have properties that aid digestion and may provide mild analgesia).

Another forum kitty called Tisha has been through similar. Her pancreatitis symptoms flared up really badly, she experienced severe inappetence and became very ill after one attempt to take her OTJ. Similar to Saoirse, she got the necessary treatments for the pancreatitis and resumed insulin therapy. A subsequent attempt to take Tisha OTJ also resulted in worsening of pancreatitis symptoms. I'm not sure how Tisha got on after that (I was moving house). Lisa is her caregiver - member name is Tisha's_Person - if she doesn't see this thread, it might be an idea to drop her a PM to see if she can maybe share some of Tisha's experiences with you.

Please let us know how you both get on. As Lyresa recommends above, keep an eye on his BG numbers.
 
Hi Shannon,

Firstly, I'd recommend in the strongest terms to keep on top of the inappetence your cat is experiencing. First up, I'd suggest taking a good note of his clinical signs - particularly signs of tense posture, meatloafing and any signs of nausea (symptom checker here) such as crouching with head lowered. Hiding is another common behaviour that may be indicative of the presence of pain. Those are some general signs, but your boy may have specific 'tells' for when he's in pain. I'd also speak to the vet about getting a supply of anti-nausea meds (e.g. ondansetron). I found that Saoirse needed support for quite a while from both the appy stimulant (cyproheptadine in her case) and the anti-nausea med (ondansetron) to help her eat. Are you giving your boy cyproheptadine or mirtazapine for appetite? If it's cyproheptadine (antihistamine) and the painkiller is buprenorphine (opiate), then the combination of the two could be making your cat more drowsy/lethargic. That was certainly my experience with Saoirse, What dose of appy stimulant are you giving, and what's the dosing frequency? If it's cyproheptadine maybe ask your vet about adjusting the dose? Saoirse weighs about 9½lbs and a dose of 1/8 of a 4mg tablet was enough to get her eating for anywhere from 8-24 hours with minimal drowsiness that wore off fairly quickly. Saoirse only ever got one dose of mirtazapine - I stopped it when I learned more about its side effect profile after she became mildly psychotic after taking it (it can induce serotonin syndrome). If that's the appy stimulant you're using it might be worth speaking to your vet about possible drug interactions (possibly do some research online, too?).

Hope that helps a bit with what to ask your vet about re the meds. BTW, Saoirse's very med-sensitive. All but the smallest of bupe doses makes her very dopey, too.

WRT worsening of pancreatitis symptoms after cessation of insulin treatment, I've had this problem and so has Lisa, Tisha's mom. Saoirse was almost asymptomatic for pancreatitis at the time her Caninsulin treatment had to stop (for safety reasons - dropping her too low but still not fully regulated). In less than 72 hours she was really inappetent and just got worse and worse. Thanks to the advice I got here about treatment and feeding I was able to get the right meds from our vets and she also started treament with Lantus. To address eating problems she had her cypro and ondansetron, the anti-nausea med being needed for much longer than the appy stimulant. Second time around I weaned Saoirse very gradually off Lantus. She still experienced a marked increase in nausea symptoms a day or so after the insulin treatment ended, and also her appetite lessened. I managed to treat her symptoms with ondansetron only and a lot of coaxing for the inappetence. It has taken a few weeks to restabilize her but thankfully she was only uncomfortable this time round, not seriously ill. She is eating very well now and only needs an occasional dose of ondansetron. She also seems to find it helpful and soothing to lick a toy containing organic catnip leaves a help when she has a bit of discomfort after a meal. (Catnip is professed to have properties that aid digestion and may provide mild analgesia).

Another forum kitty called Tisha has been through similar. Her pancreatitis symptoms flared up really badly, she experienced severe inappetence and became very ill after one attempt to take her OTJ. Similar to Saoirse, she got the necessary treatments for the pancreatitis and resumed insulin therapy. A subsequent attempt to take Tisha OTJ also resulted in worsening of pancreatitis symptoms. I'm not sure how Tisha got on after that (I was moving house). Lisa is her caregiver - member name is Tisha's_Person - if she doesn't see this thread, it might be an idea to drop her a PM to see if she can maybe share some of Tisha's experiences with you.

Please let us know how you both get on. As Lyresa recommends above, keep an eye on his BG numbers.
 
Thanks Critter Mom and every other kind soul who has posted - much love to you! I took him to the vet yesterday and he administered (orally) an ap stimulant. He said it should last for three days. NOPE! Not sure what it was but will find out tomorrow. I am giving the cat Bruprecare (UK) orally. He went quite loopy when I got him home, meowing at nothing and generally being weird. He ate loads, but not today. He has been showing all the signs that you have described. Although his lethargy has lessened. He sneaked out the door and went missing for an hour. We had to knock on all of our neighbours doors and searched their gardens. He eventually appeared vaulting over one of the garden fences. (my hair is starting to fall out!)
He was only on one unit of insulin per day and his BG have been fine. As soon as I read your posts I ran to the vet before it closed and got him some A/D critical care wet food that I whizzed up with water and syringed (unused ink cartridge syringe). I will check his BG in about an hour and see how he is doing. I hope you don't mind but I'm going to copy all of the info you have shared and post it through my vets letter box first thing in the morning. I'm so tired, I can't think straight. We slept on the kitchen floor with him last night. That's where he settled (on his heated blanket)
 
I just went through this with Tennie, but he is nowhere near OTJ. We are still so new with everything. He is a large cat- 16.8LBS, but I ended up giving him 1/2 doses of bupe, as the full 2ml dose put him out of it.
In Tennies case both ondansetron and mirtazapine helped tremendously. I did have to feed him with syringe for a couple of days. But then he started to eat small amounts on his own.
I read somewhere on the site to keep up with the anti- nausea and appetite stimulant even after they are beginning to act normally again. I think I kept giving Tennie the additional meds for about 3-4 days after he was feeling better.

You also might want to be careful of too much pain meds if you are using a heating pad.
 
Aw, Shannon. :bighug:It is very hard to see how poorly they get with the likes of pancreatitis. On the same page as you with the sleeping. I have PTSD so my sleeping is very disrupted at the best of times but it was definitely worse when Saoirse was bad. I passed out with exhaustion sitting up many a time. I also find my hair drops out when stress is worse. (eek!). What's your kitty's name?

Feeding little and often really helps. Based on great advice I got from members ShadowsMom and tiffmaxee, I initially fed Saoirse tiny, tiny meals on the hour since that can be much easier on the digestive system. Even if she was on her appy stimulant and looking for more, she only got the small amount and it worked very well. Our vet suggested plain chicken breast as an interim feed. For the first couple of weeks, I fed Saoirse finely minced home-poached chicken plus a 50-50 mix of water and the poaching broth. You could maybe try that, too. If you blitz it up in a blender to make it a soupy consistency, it could be syringe-fed. I gave her 8g minced chicken (about 1 tbsp) plus 1 tbsp broth and 1 tbsp water every hour. She got on well with it when her meds were on board and it helped to keep her hydrated (something you need to pay very close attention to with a pancreatitis flare-up). To help me get some sleep (and also to ensure Saoirse got fed in case I passed out again) I purchased some timed feeders so that her 'mini-mini-meals' would be dispensed hourly. They were a godsend then and they help keep her numbers good now. Petsafe 5 feeders seem to be the best on the market. Wish I had one! If you do go for a timed feeder, I woudn't recommend the PetPods I use for Saoirse. They're grand for her under normal circumstances (she's very quiet and gentle) but they absolutely will not offer any resistance to a cat on an appy stimulant intent on burgling their contents.

Over time I gradually increased Saoirse's meal sizes and increased the time between them. When I was trying to get Saoirse back onto a complete food, at first I couldn't find anything that wouldn't make her symptoms worse again. Eventually, on the recommendation of Eliz here, I fed her Liquivite. It's a liquid recovery food - basically a chicken meat and chicken liver soup - and it really helped her. It's very low in carbohydrates and it has a very high moisture content (c. 90%) which helps with maintaining hydration. They sell 1- or 2-tin packs if you want to try it, and some vets carry it as well (good for post-operative recovery and treating diarrhoea). Word of warning - it does have quite a high fat content and might not agree with all cats with pancreatitis. Thankfully it suited Saoirse and supplied all of her nutritional needs through the crisis. (Did wonders for her coat, which was in tatters at the start of the flare).

Another thing to ask your vet about is a course of B12 injections. They're part of IDEXX's recommended suite of treatments for feline pancreatitis. They did WONDERS for Saoirse. Here's a link to the IDEXX publication:

Treatment Recommendations for Feline Pancreatitis

It includes all of the medications that have been mentioned here and would be a very helpful document to use as a basis for discussion with your vet.

Re the appy stimulant, based on your post it sounds like mirtazapine - effects last several days and it can produce odd behaviour. Mirtazapine is a tetracyclic antidepressant and a very powerful serotonin agonist. It can induce serotonin syndrome - a potentially life-threatening condition. Keep an eye on the odd behaviours or responses if your boy gets it again - things like dilation of the pupils, excessive purring, aggression/agitation, odd vocalization, personality changes, faster heart rate. The antidote for mirtazepine is, believe it or not, cyproheptadine. It's much gentler (and safer, IMO) than mirtazapine.

BTW other board members recommended the Bristol Labs generic ondansetron - apparently their formulation gets the best results in cats. DON'T let your vet prescribe Zofran (branded version of ondansetron) - it's insanely expensive. And don't let him/her use the cost of Zofran as the sole reason to put you off ondansetron as a possible anti-nausea treatment. Bristol Laboratories generic ondansetron is recommended as the best formulations for cats. It's a human drug and you can get 30 tablets for a tenner or so in the likes of Morrisson's Supermarkets pharmacies. If your vet agrees that it's a suitable med for your boy, ask him to write an Rx for it and get it from a local pharmacy if the vet can't supply the Bristol Labs generic version directly. If what I've read here is typical of cats with pancreatitis, you may need to keep the anti-nausea treatment going for quite a while. Saoirse got over the worst of her flare-up months ago, but it's only in the last couple of weeks that she has really got to the point where she needs only an occasional dose of ondansetron. Mind you, which brand of food she eats can lessen/exacerbate nausea symptoms.

Going forward, with pancreatitis kitties it's a very, very good plan to set up a little medicine chest of anti-nausea, appetite stimulant, stomach acid treatment and possibly something to treat diarrhoea (e.g. Pro-Kolin kaolin & probiotic paste) so that any recurring symptoms can be addressed without needing to wait for a veterinary appointment. It makes the world of difference to the management of the condition well when you can give the right treatment immediately. Also I recommend finding a few foods that agree with your boy and sticking to them. If you do need to change foods, transitioning extremely slowly can help to minimise any digestive system distress/diarrhoea/nausea symptoms.
 
Same here, Andrea. The peace of mind one gets from having them on hand is priceless. There have been umpteen times since the flare-up when I've been able to stop possible recurrences in their tracks by learning her clinical signs and addressing the symptoms straight away. I think having the ondansetron to hand in the few weeks after Saoirse went OTJ was pivotal to her body successfully adjusting to the withdrawal of the foreign insulin. In the last fortnight her appetite has been brilliant and I've only given her one (precautionary) dose of ondansetron after a slight food change caused a one-off vomiting bout. (Food came up again, not the usual white foam). It's a bit of a shock to the system having a cat that enjoys her food again! I can't prove it, but I strongly suspect that the foreign insulins contributed to her nausea and inappetence problems, not just her pancreatitis.
 
Thank you so much for your help! I love you to bits xx We woke up this morning to mild lipidosis, thankfully we have the drops given by the specialist eye vet. This was probably caused by giving him Dreamies to stimulate his appetite NEVER AGAIN! I've printed out your comments and handed them into the vet. He will call me later. I'm feeding him little and often as you have suggested. Chicken breast and chicken liver with a sprinkle of Fortiflora and Nutramed (milk thistle etc). Do you think I should add any omega's to the solution? The pad he is using is a self heated one, so I don't think it should cause him any problems. His BC levels are all good at the moment. God in heaven what a roller coaster ride this is! xx
 
Yep, it's a real white knuckle ride, Shannon.

As you learn more about his (name?) responses to different foods, you'll be able to spot things that trigger discomfort. My vet has Saoirse on Nutramed as well. I'm not sure how much it's helping, but I don't think it's doing any harm. I won't be able to tell unless I taper her off it at some point down the line. In principle the Nutramed may be covering the bases from an anti-inflammatory viewpoint. The omegas also help joints, mood, etc. One of the things I find most difficult to deal with in the management of pancreatitis (and diabetes to a slightly lesser degree) is the trial and error needed to fine tune a regime for Saoirse, because when an experimental change doesn't work it's my little one that pays for it with greater discomfort and that withers me. :( You could try an omega supplement, but the response is very much down to your little one. From studying food ingredients and watching her clinical signs after eating, I've worked out that salmon oil is one of Saoirse's triggers, and the sunflower oil in Thrive Complete food upset her as well. Sarah's cat, Remi, is fine on the Thrive Complete despite probably being far more fat sensitive than Saoirse. With pancreatitis, I think the Every Cat Is Different rule may be even more applicable than for FD. If you're looking for healthy, FD-friendly treats Cosma Snackies chicken freeze-dried treat. They're just freeze-dried chicken. They are great for tempting reluctant kitties to eat. I blitz some up and keep the powdered treats in a little tub, ready to sprinkle on Saoirse's food if she's a bit hesitant to eat. Works like a charm. They're also a bit like kitty saltines for her - they never seem to upset her tummy. There were times when I just could not get her to eat. If she fasts too long, her BG spikes (liver dumps glucose into the bloodstream), so at those times I give her a small portion of the freeze-dried treats (about 2g) to help keep her pancreas ticking over and secreting basal insulin. The Cosma treats are available from Zooplus and Bitiba.

Check the carbs on the A/D food, btw, and do let us know how you get on with the vets. :)
 
Tennie spent a lot of time on his heating pad during his flair up.
Now that he is better, he doesn't seem to need it as much. (which I think is crazy, considering it is only 19 degrees F right now!)
 
That's interesting to hear, Andrea. Saoirse behaves in a similar fashion although I'm not sure whether she likes somewhere warm or cold when she's uncomfy. We've just moved house and she seems to like sitting near the radiator. In our old flat (when she wasn't doing as well as now) she seemed to prefer sitting near an outside wall (cooler?). I do know that when she sit's on the sofa she's feeling good. Recently, it has been so good to see her jump down from the sofa, have her meal and then hop back onto the sofa again. When she does that, I know that her meal didn't upset her tummy. I always feel so sad when I know she's feeling sore. :( Licking her catnip toy really seems to help her; a bit like a human taking a peppermint after a meal?
 
Interesting about the catnip. Pretty much the only way to get Tennie to play these days is to give him some 'nip.
We call it kitty crack around here. He likes the fresh leaves best, but his bother, Quall, prefers dried!
I'll have to start giving him some after his meals and see how he reacts.

Tennie has the same reaction with the sofa. I love to come home and see him sitting there because I know that if he has the energy to jump up there he is feeling ok. Now if we can just get his number s down!
Its crazy to see how much infection/ inflammation raise the glucose numbers. Tennie was doing so wee before the flair up,getting numbers in the blue, now it feels like we are staring all over again.
 
Tell me about it, Andrea. I can vividly remember the awful sinking feeling in my heart and stomach when Saoirse's numbers started heading back up when her flare started. I thought I had completely blown her chances for remission. I looked at the Alphatrak meter reading 20 mmol (160) and bawled my eyes out ... :(

I hope that Tennie will respond the same way as Saoirse did when her pancreatitis symptoms lessened. (((Tennie)))
 
Thanks Aine!
Yes, a lot of bawling going on around here in the last month!
I'm so glad Saoirse leveled out again! What a relief Huh?
Things are looking up though- just got our first yellow number in quite some time:)
 
Hi Shannon,

Maybe you might be able to help me. Over the last few days or so, Saoirse has been vocalising unusually - typically just after she has eaten or if she's been to the litter box. I was wondering whether your little one does anything similar? I'm trying to suss out whether it might be the Nutramed supplement that's affecting her this way (she hasn't been on it for very long and this is really unusual behaviour for her). I'd really appreciate it if you'd let me know whether you've noticed anything peculiar about your little one's behaviour since starting it.

How's your little fella doing today? (And what's his name??? :) )
 
First, HUGS - pancreatitis is hard. You may need to syringe feed him to get some food in him - he needs food for his body to fight this. How are his numbers since he's off insulin?

Unfortunately I can't help with your painkiller question. How about adding 'Painkiller Question' to your title to get more eyes that CAN answer. To add to your title, find the 'Thread Tools' on the right above your original post. Click on it, you'll see 'Edit' in the dropdown.

Another HUG,
Thank you for your reply and I'm sorry I haven't got back to you sooner. Sam's numbers have been fine but every time we take him down a notch from insulin he gets pancreatitis, which leads me to believe it is the type of insulin he is taking? At first it was two units. Then one, then none - each time pancreatitis. My vets (three of them) have been very responsive to all of your comment (even scanned them on to their computers) I am going in with all guns blazing tomorrow. I said it from the beginning, even my husband didn't believe me. It's the type if insulin! I'm so tired and upset. I'm not well myself. Up at 1/3/4/5 syringe feeding my cat...
 
Hi Shannon,

I feel for you. Intensive nursing and all the worry that goes with it is very hard. Have your vets prescribed anything to help Sam with eating?

From my experience with Saoirse, I do think that insulin can upset the GI tract. I haven't yet found any published research to back that up, but I have seen a lot of anecdotal evidence of insulin causing GI upsets in human diabetics. Saoirse has been insulin-free since the beginning of December. Her nausea symptoms definitely got worse when insulin was withdrawn - and that applied to BOTH Caninsulin and Lantus. I also found it striking that a significant number of caregivers posting on Feline Health since I joined FDMB back in June report problems of nausea and inappetence in their cats after starting insulin therapy. And not all of the cats had a Dx of pancreatitis either.

I think I mentioned above that the second time around I reduced Saoirse's insulin dose very slowly (shaving the dose by less than 0.25IU Lantus at a time). It helped. She was also taking Bristol Laboratories' generic ondansetron second time around so I was able to help her through problems with inappetence (she needed a fair bit of coaxing for a couple of weeks and lost 0.3KG during that time). It is only in the last fortnight that she has returned to eating as comfortably as she did prior to instigation of insulin therapy last June.

I hope some of my experience and observations will help you as you work towards finding a way to help Sam. I really do recommend the ondansetron treatment. Sending prayers that Sam will start eating better very soon and that you'll be able to get some desperately-needed rest. I know how exhausted you must be.

((Shannon and Sam))
.
 
Hi Shannon,

I'm just checking in to see how you and Sam are both doing? Has there been any easing of symptoms and have you managed to get any rest? It's really, really tough going. I was in pieces when Saoirse was at her worst I've got health problems, too, and the combination makes things even harder. (((Shannon and Sam)))

I wanted to share some info on Saoirse's problems with Nutramed. It might be helpful to you and your vet.

As I posted above, a week or so ago Saoirse started mewling after eating (and sometimes before and after pooping). She also started hiding intermittently. A few days later she developed a ravenous appetite - akin to polyphagia or when an appetite stimulant is working. Her BG started to climb a bit over the course of the day and eventually went outside the normal range for the first time in months (8.8). over the last few days. This is not normal behaviour for her and I was worried about her higher BG. Also her abdomen has been getting a little distended again. I had to give her a 2mg dose of ondansetron (for nausea) for the first time in weeks after she gorged a bowl of food that should have lasted 6 hours in one sitting. I check her faeces every day to monitor her pancreatitis. Her stools looked fine externally but the segments were getting a bit soft and whiffy again. The outside of the stools would be dark brown, but breaking open of softer segments revealed a medium-dark tan colour and markedly whiffy. Her coat condition wasn't quite as good as normal.

I decided to see if the Nutramed might be the problem so I cut down the dose (had been on ½ capsule per day). Her appetite reduced back to normal within 24 hours and her BG numbers were better. I continued to reduce her NM dose gradually. Within 48 hours her stool quality improved (not as smelly, and inside of stool was back to a dark brown colour with only a hint of tan). The mewling has all but disappeared.Her abdomen is slightly less distended. Her BG numbers are better but not quite as good. The hiding behaviour is reducing. Her coat was a little uneven on the first day or so of the reduction, but it seems to be improving again now.

Based on her clinical signs, I think in Saoirse's case one or more of the ingredients in the Nutramed is irritating her GI tract. I've decided to discontinue it in the hope of finding a better treatment. I just wanted to share this with you so that if your vet and yourself are trying to find and eliminate things that are causing Sam digestive distress at least you'll have one case report where one or more of the ingredients in Nutramed may be a candidate. I know how much of a struggle it can be to find triggers and I wanted you to have a record of this one on file, just in case. :)
 
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