OTJ Trial Nico Day3 am-67/pm-96

Tyleete

Tyleete

Member Since 2025
My little man chilling. He's doing so much better these days. Rhomping around, playing silly with his fur family. It's great!
Happy surfing everyone!
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Monster's Mom said:
This makes me so happy
Happy day 3💚
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Me too! I just got back from the vet with another 2, and she could hardly believe it. Wants me to wait a week and then bring him in for just her to do a glucose test.😅 Not sure I will because those car rides are traumatizing to them all. I don't need her to officially tell me what I will know if he has 14 days straight of perfect numbers.
I certainly need a break with all the other problems. Vet said my cancer kitty's intestines are even thicker. :( So we're probably going to start the chemo real soon then.
This was one of my gals I took in. Needed a test for possible heart disease. My cats have issues
 

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Great report on Nico! Keep on keeping green sir!

Sorry to hear the vet visits aren't being reduced. :bighug: Make sure SCL kitty has a good supply of ondansetron to help with the chemo. Are you doing the every two weeks method of dosing? So much easier on kitty and human. Some of the current practice is to stop chemo after about a year if in remission.
 
Wendy&Neko said:
Great report on Nico! Keep on keeping green sir!

Sorry to hear the vet visits aren't being reduced. :bighug: Make sure SCL kitty has a good supply of ondansetron to help with the chemo. Are you doing the every two weeks method of dosing? So much easier on kitty and human. Some of the current practice is to stop chemo after about a year if in remission.
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It's scary, the chemo route. This is my 3rd (&probably getting a 4th diagnosed Monday) and we've always done 4mg of Chlorambucil once weekly. My original oncologist (moved to Australia) had me giving pills the first year till she remembered it was a fraction of the price to get it compounded.🙄 My first girl was on this for nearly 6yrs. We had never tried taking her off it. She did great and with the help of cbd, we're able to get rid of the Pred even. She eventually passed from kidney failure. 2nd was on it for 4yrs. Doc took her off it twice. First time we had put her back shortly after. her suspected (and rather new) skin cancer got huge after and she withered away. Same dosing. Both great worked while on it.
Not exactly sure what we're doing this time. But in truth, I've never liked the idea of pulse dosing that I've seen some do. And for both previous ones, you could tell the dose was wearing off the 6th day. :(
 
There is an article by Dr. Timothy Stein that talks about every 2 weeks dosing. The dose is based on cat size which loosely relates to weight. My 8 lb kitty got a 4 mg dose every two weeks, until we stopped 2.5 years ago, originally diagnosed in 2018. It's apparently also what is documented in the last couple editions of the feline oncology textbooks. Once weekly isn't even a researched protocol. The every other day dosing method is hard on kitties, not only more chemo overall, they don't get a break from the nausea. Neko started on the EOD (IM vet insisted) but after a month I leaned on him to OK the every other week method. After day 5, she was no longer nauseous and we had the rest of the 2 weeks without ondansetron.
 
Wendy&Neko said:
There is an article by Dr. Timothy Stein that talks about every 2 weeks dosing. The dose is based on cat size which loosely relates to weight. My 8 lb kitty got a 4 mg dose every two weeks, until we stopped 2.5 years ago, originally diagnosed in 2018. It's apparently also what is documented in the last couple editions of the feline oncology textbooks. Once weekly isn't even a researched protocol. The every other day dosing method is hard on kitties, not only more chemo overall, they don't get a break from the nausea. Neko started on the EOD (IM vet insisted) but after a month I leaned on him to OK the every other week method. After day 5, she was no longer nauseous and we had the rest of the 2 weeks without ondansetron.
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Geez, that's some long reading. I'm just under halfway. But from what I've seen so far, they or cats at 20mg once every other week? That's so much.😮
And I was also reading how B12 can help with digestion? My doc had suggested probiotics to help. Would they do the same thing? I've never given or heard of B12 for cats with Cancer before.
I've got cat chores, so will have to come back to the article after. But a 2011 artifice seems a long time ago for a medical research paper, no?
Thanks
 
Monster's Mom said:
Aw! They have a wonderful caregiver!
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I can promise you, they don't think so.😅 Goofiest part, is to take her to the vets, requires 2 humans. 1 to drive, and 1 to stay back there with her. She WILL throw up at least once, have puddle poop at least once, and froths at the mouth. Hence the bib so I don't need to bathe her after. Sometimes. If I'm not there to immediately pick up that mess, she'll sit or step in it & she's a medium haired cat. What a mess.
Cats.
What can you do.
 
Tyleete said:
I can promise you, they don't think so.😅 Goofiest part, is to take her to the vets, requires 2 humans. 1 to drive, and 1 to stay back there with her. She WILL throw up at least once, have puddle poop at least once, and froths at the mouth. Hence the bib so I don't need to bathe her after. Sometimes. If I'm not there to immediately pick up that mess, she'll sit or step in it & she's a medium haired cat. What a mess.
Cats.
What can you do.
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Poor baby!!! Goodness! Have you tried something to calm her, like gaba? It doesn't really work for Jude, who also has taken to either having diarrhea or urinating in the crate when I take him to the vet.
 
Tyleete said:
But from what I've seen so far, they or cats at 20mg once every other week? That's so much.😮
And I was also reading how B12 can help with digestion? My doc had suggested probiotics to help. Would they do the same thing? I've never given or heard of B12 for cats with Cancer before.
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The 20 mg once every other week would be a VERY large cat. What you read is 20mg/m squared of size. There is a table that gives a dose based on weight, which is an approximate conversion from meters squared. Neko was on 6 mg and even a 17 lb cat is less than 8 mg. The 2020 Small Animal Clinical Oncology textbook also references the same method. 2011 is when the research was published. I belong to an SCL group that keeps up to date on recent research and no new dosing protocols since 2011.

Many IBD or SCL cats test low for B12 - you might want to get a cobalamin or B12 blood test done to check it. If you supplement, it can help their appetite, that is, if they are low on B12. And help them absorb their nutrients better.
 
Mary & Jude said:
Poor baby!!! Goodness! Have you tried something to calm her, like gaba? It doesn't really work for Jude, who also has taken to either having diarrhea or urinating in the crate when I take him to the vet.
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Yup, we tried half a tablet of Gab, even though I hate that stuff. I know it serves its purpose (usually), but it made one if my cats nearly cross-eyed permanently after taking it once. But yeah, made no difference for her either.
 
Wendy&Neko said:
The 20 mg once every other week would be a VERY large cat. What you read is 20mg/m squared of size. There is a table that gives a dose based on weight, which is an approximate conversion from meters squared. Neko was on 6 mg and even a 17 lb cat is less than 8 mg. The 2020 Small Animal Clinical Oncology textbook also references the same method. 2011 is when the research was published. I belong to an SCL group that keeps up to date on recent research and no new dosing protocols since 2011.

Many IBD or SCL cats test low for B12 - you might want to get a cobalamin or B12 blood test done to check it. If you supplement, it can help their appetite, that is, if they are low on B12. And help them absorb their nutrients better.
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I'll continue reading in the morning. Hasn't gotten to the table yet and that number startled me.😅
I'll have to look back at her latest tests to see if she had that tested. Last year I paid to have all (at the time) 12 and tested. And Angel is one that gets tested more often, so I might have a recent one. I still have 7 and they go through so much testing, I can't recall offhand who's had what except things like xrays and ultrasounds.
It's weird though. To give only every other week. Surely the Chlorambucil doesn't last in their bodies for two solid weeks. And the fact that Neko didn't have to take Ondansetron after the first five would go towards that I would think?
 
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