New vet for Boo wants change from PZI to Lantus

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Jane & Boo (GA)

Member Since 2009
I have ordered from Mark's Marine and will have a few days to learn about Lantus. I've read all of the stickies and plan to go the start low/go slow protocol. Based on her PZI history of numbers, should I start her at 1.0 U or .5 U?

Since her diagnosis 5 months ago when I took her in as a rescue, we have taken care of dental issues, a skin infection from over-grooming, the over-grooming is under control now, and she has put 2 healthy pounds on what was an emaciated frame. She is 100% healthy other than the diabetes.

With the PZI I've not been able to get her regulated. There would be periods of consistency, but PS always ended up higher than I want. Nadir would usually be at +4. To decrease PS numbers, I would increase the dose by a smidge and that would be OK for a little while, but then we would have a serious drop into hypo territory at +4 for no apparent reason. Since I'm at work all day, I can't be around to check for those sudden lows. On May 6 she was at 94 at +7. Lord only knows where she was at her usual +4 nadir. :nailbiting: And then last night at the new reduced dose she went from 241 PS to only 234 at +5. :banghead: Seems like, at mid cycle, 1 unit becomes too much while .8 becomes too little, but PS numbers always remain too high regardless of which dose.

Anyhow... because of all of that, the new vet suggested Lantus and I'm willing to try anything to see if Boo can reach consistency and stay in a good range of numbers. I will do cart wheels if I can get her to stay in the blues from PS to PS. I look forward to the good advise I know is forthcoming. :cat:
 
Boo eats homemade raw. This is what is advised in the "Start Low, Go Slow" sticky in the Lantus/Lev forum
  • If the cat was previously on another insulin, the starting dose should be increased or decreased by taking prior data into consideration.
Based on my prior data, I know that .5 of PZI is too low. Should I expect that to be the case with Lantus? Or do cats generally have a whole different response from the Lantus that would warrant falling back to that low of a dose?
 
Lantus is a depot insulin sot it takes 3-5 days for the results to be fully shown.
Theoretically, one unit of ProZinc should have same overall effect on lowering BG. However, ProZinc typically has a definite curve like you are seeing. Lantus, and Levemir too, typically have a relatively flat curve because of the depot effect so it is hard to really compare the different insulins.
I myself would start at 3/4 unit
 
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