I need some help and guidance for Lorenzo. I was able to get a couple of home glucose tests done but, for the most part he is getting "nasty" and making it impossible. At the last trip to the vet he was very hard to handle as well but of course they were able to draw blood. It took 15 min, two of the most experienced techs and the vet. They used a towel and gentle restraint because he just was not cooperating (hissing, growling, pulling away). I am wondering if I will ever be able to test at home do to his extreme reaction to any type of handling or restraint that he perceives as threatening. I am waiting for a reply back from a home visiting vet to see if I might be able to get some professional assistance. It is worth a try if the service is available. My concern is that the more we handle him, the more he seems to be reacting with the insulin injections as well. I will order an illumavein in the hope that it might make a difference. Are there some cats that just won't allow all of the testing? His personality is pleasant and he never acted aggressively although he has never liked to be held unless it is his idea and never liked to feel restricted. I am waiting for the delivery of Purina Glucotest for testing the urine although I know it doesn't replace blood testing. The dosage of insulin has gone up from 2 units to 3 units to 4 units 2x/day which is frightening without getting the daily tests done. He tested at 420 midway between injections at his last visit so the vet said "let's keep him on the 4 units 2x/day and check him in 2 weeks". I would like to get a second opinion from a vet that specializes. Maybe a phone consultation. I am waiting for a reply from a couple of vets that I consulted. He never had a profile done but I am not sure how accurate that would be if he is so agitated the entire time. I just don't know, I want to be aggressive, but at the same time I don't know if Lorenzo is the best patient for that approach. I am watching closely for hypoglycemia but during the night and a few hours a day when I am not home this is not possible. On a positive note, he seems to be feeling better, drinking less water, urinating less, moving around more, grooming himself like before. His food has been converted to 75% canned diabetic, 25% previous dry food. We are working towards 100%. He is eating well, right on schedule. If anyone can offer some insight or suggestions I would greatly appreciate it. LISA