(((Jamie))) - I feel for you with all my heart; you're both going through a real baptism of fire at the moment. I've been through similar and I understand how hard this is to go through.
I agree with Kris; the priority is to make sure Willy gets enough to eat. For now the right food is the food that Willy will eat. As Kris observes above if you can get him back to eating little and often it should help break the nausea-inappetence-further inappetence-further nausea cycle that sets up when a cat has trouble eating.
Cyproheptadine can help with appetite stimulation and it's easier to control the degree of appetite stimulation than with mirtazapine (shorter half-life, milder effect, small (weight-dependent) doses of cypro can be given up to 3 times a day). For information, mirtazapine can induce serotonin syndrome.
I suggest talking again with the vets treating Willy to see if pancreatitis is a problem. Also you really, really,
really need to check him for ketones every day to make sure you don't end up dealing with complications like hepatic lipidosis or
diabetic ketoacidosis (DKA). (For information, one should call the vet straight away for advice if trace result but any higher than trace you need to get a cat throwing ketones to a vet immediately for emergency treatment.)
Here's a checklist of things I'd want to work on at home and with my vet if my kitty were in this situation:
1. Twice daily check for ketones in urine.
2. Make sure vets run a pancreatitis test.
3. Make sure cat's mouth isn't sore and that it can smell food OK (warm food if necessary).
4. Monitor for clinical signs of discomfort (especially after ingestion of any food) - meatloafing, hiding, lethargy, general
nausea symptoms.
Did the vets examine Willy's abdomen?
5. Anti-nausea treatment - Cerenia AND ondansetron should be considered (ondansetron takes a bit longer to kick in than Cerenia but it suits some cats better).
6. Ask about steroid treatment and working the insulin around it to address IBD.
7. Ask about treating on an 'as if' basis for pancreatitis and getting the cat some pain relief (buprenorphine) and also an appetite stimulant (as discussed above).
8. Make sure that constipation is not the issue. (A
short course of metoclopramide can help with this.) Poor gut motility can be a problem with some diabetics.
9. Ask for a course of B12 treatment.
10. Make sure kitty continues to be properly hydrated. Ask vet for input on this as dehydration can make a kitty feel worse.
Here are helpful links:
IDEXX pancreatitis treatment guidelines.
www.ibdkitties.net
Even if pancreatitis is not the issue the IDEXX document contains very helpful information on the right treatments to request from your vets for a nauseated cat (nausea being the most common problem in a cat with pancreatitis).
If you can get the right supportive treatments in place it could make things much better for you both.
Sending more prayers for you both. I know from experience how scary and stressful situations like this can be.
Mogs
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