One of the members of the Lantus forum asked me to stop by.
A couple of thoughts that I don't think anyone has mentioned. First, it's great that you started home testing and that you're successful. As an FYI, you don't want to actually poke the vein in Murphy's ear. You want to try to poke between the vein and the rim of his ear. If you poke the vein directly, you'll get a lot more blood than you need. It also takes a while for an ear to "learn" to bleed. I'm guessing that the more you poke, the more capillaries develop and the easier it is to get blood.
I would NOT rely on the urine glucose monitoring method. It is notoriously unreliable. The following quote is from the 2005 Position Statement from the International Diabetes Federation.
International Diabetes Federation said:
Limitations (of urine glucose testing): These include that urine testing gives the results since the last time urine was voided. If the urine is free of glucose, it is an indication that the blood glucose level is below the renal threshold, which can vary, but is usually accepted as corresponding to a blood glucose level of 10 mmol/l (180 mg/dl). Results also do not distinguish between moderately raised and grossly elevated blood glucose levels. A particular concern is that a negative test does not distinguish between normoglycaemia and hypoglycaemia.
Further, if you are concerned that numbers are even lower than 180, you have no way of ascertaining "real time" glucose levels using urine monitoring. By the time urine is processed, which takes several hours, your cat could be severely hypoglycemic. Similarly, urine testing does not give accurate readings at the upper ranges of BG levels.
As others have said, glucose curves done at the vet's office may be effected by stress. I would test before you take your cat to the vet for a curve and then see what the results are at the vet's office. My cat's numbers run much higher. Also, because I home test, my vet does not ask that I bring Gabby in for curves. I have much better data from home testing AND I'm saving a great deal of money by doing this myself.
Also a note about your meter. I would not assume your meter is any less accurate than your vet's. If your vet uses an AlphaTrack meter in the office, the calibrations are a bit different. However, the Lantus dosing protocol based on the research conducted by Jacqui Rand, DVM at University of Queensland, is the what the
dosing protocol used on the Lantus board is based on, has parameters for both human meters and the AlphaTrack meter. Use the numbers your meter is giving you.
As Carolyn has pointed out, testing is essential for the safety of your cat. Big jumps in dose can create big problems in resulting BG numbers. Unless you are carefully monitoring, you could have a very difficult situation on your hands. An overdose of Lantus can easily take 16 hours of aggressive monitoring (i.e., testing every 15 - 30 min) to keep your cat safe. It is an exceptionally difficult situation for someone new to feline diabetes as well as those of us who will not leave you to handle this on your own for those 16 hours. We are committed to helping you to keep your cat safe. The dosing protocol that I linked is based on published research and is well recognized in the veterinary community for its ability to facilitate remission and for keeping cats safe in the process. At minimum, you should be getting a pre-shot test and at LEAST one test during each 12-hour cycle. With numbers in the 100s, given the large dose increase, if this were my cat, I would be testing aggressively -- at least every 2 hours -- so you have a clear picture of what's happening.
As far at the demodicosis, while Gabby didn't have mange, she did have ringworm. I spent more weeks than I can accurately remember using the sulfur lime dip to get rid of the fungal infection. Unless it exacerbates Murphy's asthma, it's not as bad as it seems. Do you know whether you need to disinfect your home, as well?
dvm360.com said:
Many cats with D. cati mites will experience resolution with control of their underlying metabolic disease, so identifying and managing this is critical. Nevertheless, treatment of the demodicosis may also be necessary. As with D. gatoi, 1.6 percent to 2 percent lime sulfur dips every five to seven days for four to six weeks is a recommended and effective treatment; 0.0125 percent to 0.025 percent amitraz applied every four to seven days has also been used to treat demodectic mange in cats but carries a significant toxicity risk and is generally not recommended.
Other treatments for Demodex species in cats have been discussed, including subcutaneous doramectin injections given weekly for up to three treatments, selamectin applied topically for multiple treatments and ivermectin given orally for varying time periods. However, for both safety and efficacy reasons, most veterinary dermatologists appear to recommend lime sulfur dips as the best treatment option.