Murphy Neuropathy Getting Worse

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msmurphy2010

msmurphy2010

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Hi all. Been a few days, but my girl is doing so well. I cannot believe how well her BG has been controlled and I'm not sure if it's the Vetri-DMG, or if it's just her, but something is helping.

Her neuropathy in her left front paw has gotten much worse. She has started holding her paw up, cannot get comfy with it, and I noticed this a.m., that where they shaved her front paws for her IVs when she was in the hospital, the fur on her left paw isn't growing pain, which to me means that she does have some severe neuropathy or nerve damage from the missed Dx.

I take No-Shot B12, both cyno and methyl, but I'm not sure how much I should be giving her. Most of what I've seen on the internet has flavoring in it. The No-Shot has no flavoring in it. Or, do any of you give B 12 methylcobolomin injections? It seems that the regular B12 Cynocobolomin just isn't doing the trick.

Lisa
 
Neuropathy takes a while to improve. You have made good progress so don't get discouraged by one symptom. I just want to make sure I understand....do you think Murphy has neuropathy in just one front paw? Usually they get it in both front or back feet. If it is just one paw it might be be neuropathy. Is it the paw the IV was in? It might be a left over effect from the site wgere the IV was put in. If it doesn't look swollen or infected I would give it a few days. Wounds in diabetic people take longer to heal and I assume it is the same with cats. I have no experience with B12 so hopefully another reader can help you with that question. :-). Jan and kitties
 
I agree with Jan in that it may not be neuropathy since It is symmetric (same left and right) and usually rear. A vet visit may be in order.
 
Her vet did say that she did have quite severe neuropathy in her front paws, bad gait on the back, but that has improved. The left paw was the one I noticed before she went into the hospital. She holds it up and can't put weight on it some times, and so with the gnawing on her paw and the shaking of it, and the fact that she's holding it up, led us to believe that she did get it in her front paws. So, I guess I need to find a B12 methylcobolomin that doesn't have "milk" in it, because milk turns to sugar. She's been getting the B12 cynocobolomin shots, but I think that's only helping her energy. Otherwise, yes, she has made significant progress. I'm so happy for her.

She is hock in all fours, but the back are getting better than the front.
 
I am glad Larry understood I was trying to say it probably isn't neuropathy. My brain probably had neuropathy late at night when I was trying to write this. If Murphy continues to favor one paw for more than another day I would have it checked out at the vet. It is not that unusual for the site where IV or ports are inserted to get infected. Even when your cat improves there will still be some bumps in the road. My cat is doing generally good but still gets skin ilesions that get infected. I guess I have to help keep my local vet hospital in business!! LOL
 
Her vet looked at her paws last week when I took her in, and she said it did not appear that there was infection, but I think she (and I both) are convinced that it is neuropathy. It's always been that left paw, and it was bothering her before she was in the ER at the end of August. I'm trying to find a B12 methylcobolomin, but they all have milk in them, which converts to sugar. Any ideas? The only other thing I can do is get a compounding pharmacy to get me the real B12 methylcobolomin with no additives. I suppose that would be smartest. What's weird is that on the left paw, the fur isn't growing back.
 
It sure doesnt sound like neuropathy to me. Trouble never chewed on his paws or shook them...But *I'm not a Vet* but this still sounds like something else.
FWIW we gave Trouble 5mg's of cherry flavored MB12 twice a day and it never raised his BG' levels. If BG levels are normal neuropathy usually rights itself. No? ECID.

Sending prayers this get resolved For Murphy
jeanne
 
Her BG levels are about as normal as they can be. I would say that as new as her DX is, she's doing quite well. I'm certain that it is neuropathy, because I have it myself from a nicked thoracic nerve when my thyroid was taken out. It's not a shaking, it's a zapping pain, that is like an electric voltage. The gnawing is part of it, which started quite a while ago before she had her Dx. We're only into 3 months of treatment, so this may resolve over time, but whatever it is, it isn't happening quick enough. Otherwise, she is doing wonderfully.
 
Question for you -- could someone give me the best B 12 methylcobolomin sublingual they are using and the dosage? I spoke to a compounding pharmacy this a.m., and my vet is going to prescribe .25 ml injection once per week. Her little left paw -- the fur isn't growing back and she lifts it up like it hurts her. Poor thing. Does anyone use B12 M injections? Most of the sublinguals have milk in them which convert to sugar. Need to be careful. Thanks.
 
Oh, sorry - take a look at progress. This diabetes thing was so stressful, but Murphy and I are doing well. She wanted me to post her photograph from the other day to show you all how hard she's trying to get better. This picture says a thousand words (at least I think so) compared to how she looked in August. Thank you all so, so much for helping us along the way. We're still learning.
 

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From reading, and speaking to a local neurologist, you can't give too much Methyl B12.. so don't worry about overdosing. Just be a little careful about overdoing it with pills that have other stuff in them, ie milk, other things that convert to sugar, sugar itself, etc.
I personally gave my cat Xobaline 3mg 2 times a day. He was in pretty bad shape, and could barely walk because of his back legs. It wasn't even 2 weeks and he was back jumping up on my counters.
Once I got his numbers well under control I just stopped giving him the Xobaline and he is still just fine.

Good Luck.
 
Where do you fine Xobaline? If I get the compounded liquid B12 methyl, it would really truly be a cost savings, something like $24.00 for a 30 ml vial. Another compounding pharmacy wanted to charge me $75.00. Most of the B12 methyls I've seen, even the No-Shot B12 I take, which is BTW, awesome, have milk in them. I guess it would be safe to say that this is why the fur didn't grow back on her left paw When I had my thyroid removed from cancer last year, they nicked my thoracic nerve, and I have no hair on my legs, not a bad thing, eh?

Anyways, as far as the overall scheme of things, she looks better than I've ever seen her before. And, I was not going to give her any more of that Ivermectin poison. Instead, the Vetri-DMG, which has kept her BG stable and made a huge difference in her all around.

Happy days!
 
Well, if you do a web search for it ... here's 1 place:
Hammer Nutrition

and if you do a search on "methylcobalamin spray" you'll find lots of options.
 
It may be worth a consultation with a vet. Neurologist if there is one in your area. Another idea- people with Peripheral Vascular Disease (PVD) often get a syndrome that has many symptoms like neuropathy. I assume cats can get the same? If people or cats have a poor blood supply to extremities it could cause a whole variety of symptoms lke muscle weakness, numbness and poor healing. I have never heard of neuropathy or nerve damage per se causing hair not to grow.

There have been several recent posts about neuropathy; I am going to start my own post to see if anyone knows if Duloxetine HCL has ever been used to treat neuropathy in cats.
 
My neuropathy from surgery last year did stop the hair on my legs from growing. We did nerve conduction studies on my legs and it came from nicking my thoracic nerve. I'm taking No-Shot B12 cyno and methyl, and it does really help. So, her vet is going to call me tonight.
 
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