Hi! I have a difficult case, I think, and could use any and all advice. My 14-year-old cat, Tommy, was diagnosed with diabetes about two years ago. He is a LARGE cat -- about 20 pds. In the beginning, we started him on Lantus at 3 units twice a day, and eventually started to see his counts stabilize (125-150) around 8 units. But after about a year, the Lantus seemed to stop working. The vet believes he is now insulin-resistant. Tommy is now up to 10 units 2x day, which is obviously a very large dosage, but his sugars are still routinely 400-450. He had neuropathy in one leg that seems to have gone away (he was limping for a while but now back to normal). Otherwise, he does not have any complications, has a VERY healthy appetite, drinks a lot of water (as would be expected), and otherwise seems content. He does have HORRIBLE diarrhea, however, which is EXTREMELY foul-smelling. We have tried multiple antibiotics to address the diarrhea but to no avail. He eats Royal Canin diabetic cat formula. He's always had a pretty sensitive stomach, but my guess is that the diarrhea is a function of his out-of-control glucose levels, so if we could just get that down! .... Anyway, Tommy *seems okay, but I'm a Type 1 diabetic myself and I know how awful it feels to have high blood sugars, so it's all just very frustrating...