Lantus - inconsistent numbers + injection site variations

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nepenthe

Member Since 2010
Background: I've tapered my cat off of 5mg prednislone EOD last week. Since he was on the pred 2 yrs ago for chronic pancreatitis, his numbers have been up and down. Like sometimes as low as 108 the other morning and as high as 410. ( I am testing using the AlphaTrak meter)

There is a lot of other weirdness going on - eg, today, he was at 235.8, gave 1.75 units Lantus and then just now at +6 he was 410!

One thing I am wondering about is that it seems that whenever I inject him on the same side in his flank-in the same area, I get more consistent readings. Whenever I move the shot to the other side, where I might not have shot for the past 5-6 shots, I get higher numbers.

Could it be because Lantus is a depot insulin, that the shots build up in an area and work better - and when a shot is done on the other side of the body, there are not enough recently accumulated amounts of insulin at that site, making that shot weaker? (or, more specifically, effecting overlap somehow?)

(I literally think I am going to go crazy before I get this cat into anything that resembles stability, at least below the "renal threshold", as the past 2 yrs of pred have caused such consistent hyperglycemia that his ultrasound from last week is suggestive of the early stages of kidney failure (his numbers are normal, but his USG is 1.031, and his kidneys show some inflammation, "medular rim sign" etc..))
 
Re: Lantus - inconsistent numbers + injection site variation

It would be easier if we were able to see a larger sample of your cat's test numbers in order to get a better sense of what you're seeing.

I have a couple of thoughts. First, how old is your insulin? If your insulin is toasty due to either age, a manufacturing defect, or it's been somehow damaged, you can get inconsistent numbers. There may be some bouncing going on. In order to know if bouncing is the reason for the highs and lows, seeing a larger sample of numbers would be very useful.

There may be better or worse spots when it comes to the absorption of the insulin. It's not so much a matter of the insulin depot -- as long as you've been giving insulin consistently and the insulin is still potent, there's a depot. It may be that the one flank just doesn't absorb as well as the other. I recall another member mentioning at one point that their was a spot on their cat's scruff where if she shot there, it was like giving a fur shot. So, what you're experiencing is entirely possible.
 
Re: Lantus - inconsistent numbers + injection site variation

I know I just bought the insulin like 30 days ago.

This business of bouncing is something I am suspecting - from what I understand, its a type of rebound, but not chronic (like somogyi etc)

How would I go about making a SS for Lantus relaxed protocol? (is there one that converts numbers to International ones?)
 
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