My cat Jason has a suspected insulinoma. He's been OTJ for 5 and a half years, and last year he had a hypoglycemic seizure. When it happened I didn't even consider that he might be hypo because he wasn't on insulin and had been eating normally. I happened to run his biannual bloodwork that day, and got the results about 2 hours after the seizure which showed low BG; I immediately tested him with my home monitor and found he was still in hypo numbers. My vet did an ultrasound to try to find the tumor, but wasn't able to see it. He couldn't think of any other possible causes for a hypoglycemic seizure in a generally healthy adult cat that wasn't on insulin. The only other possible way for us to diagnose it was to do an exploratory surgery but as the internal medicine specialist put it she wasn't about "to go poking at a 17 year old cat's pancreas" (which my vet and I agreed on), hence why Jason's tumor remains suspected instead of confirmed.