Injectable prednisolone

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Linda and Bear Man

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My civvie, Miss Emily, is very ill with pancreatitis and inflammation of the liver, stomach, and intestines. She has elevated PLI and liver values. We have started her on Prednisolone. She is very inappetant, cannot be pilled or syringed, and it is a struggle to get her to take the tablets by mouth in a pill pocket. I have asked the vet to order injectable prednisolone. I have read that it stings. Has anyone else used this, and is there anything else concerning about injectable prednisolone as compared to oral prednisolone? The vet is able to order it, but they have not used it before. I have used injectable Dexamethasone, but the vet does not want her taking anything that strong. The steroids are going to be risky for her, at age 18 with a history of pre-diabetes, CRF, and pyelonephritis, but I was afraid I was going to lose her over the weekend with her refusal to eat. She is looking better today after a couple of doses of the pred. Since she is so good with injections, I am wondering if injectable pred is a good substitute for oral pred.

Note: she is also on sub Q fluids, famotidine, buprenorphine, metronidazole, and ondansetron. She did five days of cerenia.
 
Will she eat anything...

You can crush up the dose and mix it into a small amount of
Baby Food Chicken or Turkey (no pork). About a teaspoon.

Then perhaps she will eat it up on her own.

Or if not, you can force-feed. Finger Feed by putting a pea sized dab
on the end of your fingertip. Open mouth as if to pill her, but scrape the
bit of food onto the roof of her mouth just behind the upper front teeth.

As far forward as possible and just behind the upper front teeth.

Now let go of her head and allow her to swallow a few times.
Repeat with next dab of food.

Also, any fingers that are going into her mouth, or prying it open, should have
the fingernails cut as short as possible....yes, you will have to give up your manicure for
your baby. I mean really, really short fingernails. The roof of kitty's mouth is
very sensitive and you do not want to cause pain.
 
Her eating is very unpredictable. She may lap up some liquid, or refuse. Baby food isn't working. She is also very sensitive to meds in her food - she knows it is there and will go off the food (even when she was feeling better). She is taking a bit of watered down recovery formula, and some Temptations, so my best bet is to try the pill pocket covered with crushed temptations. It takes a lot of coaxing.

No one opens Emily's mouth. She is extremely head shy. It would be a physical battle. The vet has trouble even opening up her lip on the side to look at her teeth.
 
We currently have our Mr Mittens on pred and he will not eat treats nor food that smells funny to him so our vet had it compounded into PLO gel I think its called. We rub on the inside of his ear. Could your vet get something like that done? It sounded like steriods were some of the easier meds to get that way.
 
Before Norton started on oral Pred, he was given a steroid injection:

from vet report:
given 1.0mg/kg SQ Dex SP

so this is probably Dexamethasone. It worked for him -- it does last several days.
 
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