Re: Bucky's diabetic again
Aren't the insulin shots supposed to be consistant so that the insulin builds up or no?
Only some insulins have a depot effect or buildup as you called it. Lantus and Levimir. None of the others do. They are what we refer to as" in and out" insulins. Once they are used up, they are gone and out of the system.
I don't know if there are many or any people using the new vetsulin, so I can only guess that's it's more like the old variety and like caninsulin or the PZI vet insulins where there is no buildup.
There is no change in the 'new' vetsulin. Still the same as before. Only brought back to the market with improved quality control in the manufacturing process.
http://veterinarynews.dvm360.com/dvm/article/articleDetail.jsp?id=811353
http://www.vetsulin.com/PDF/Vetsulin-Feline-Conversion-Chart.pdf
Here is the old post from the Vetsulin/Caninsulin user forum
http://felinediabetes.com/FDMB/viewtopic.php?f=19&t=302 Since this was written 4 years ago, many more caregivers and vets have been using the better insulins like Lantus and Levimir.
Most everything I can find talks about how it was developed for dogs. So although it has been FDA approved for cats, the basic reason we do not use Vetsulin much in cats is because it's duration wasn't long enough with cats' more rapid metabolism compared with dogs.
Yes, there are a couple of new people on the board using Vetsulin but they are very inexperienced in the management of diabetes.
The one change that Merck made in the administration and dosing instructions was to thoroughly shake the vial to mix the insulin. No changes to the actual formulation were made.
I do understand that some people look at the lower upfront cost of insulins like Vetsulin and Novolin N. In my opinion, the lower cost is offset by the lower 20-30% remission rate in cats, and potential longer term costs of vet visits and diabetic supplies if your cat needs to stay on insulin for the rest of their life. Some of the longer duration insulins give a much higher chance of remission, from 70-90%. That is why they are recommended here.
Slideshow presentation by U of Q on the pros and cons of the various insulins here:
http://www.uq.edu.au/vetschool/content/clinic-stlucia/feline-dm.pdf Here is a brief quote from the University of Queensland article on Vetsulin/Caninsulin
Good clinical but poor glycemic control in many cats
• Vetsulin/Caninsulin : Porcine, Lente
• Registered for Vet use – Europe legal
requirement that 1st insulin used
• Many cats good control of signs q12hr
• More accurate dosing
– 40 U/ml versus 100 U/ml
• More predictable than PZI
• In most cats has too short duration
for excellent glycemic control q12hrs
• Remission rates 20-30%
• 4th choice insulin for cats
With a cat that has fallen out of remission, it is important that you get them back into control ASAP. IMHO, I would not choose Vetsulin to accomplish this.