Hi, Squamee and I are back.

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judy and squamee(GA)

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Hi all. Most of you don't know me, as I was here last year, and have been mostly gone since Aug 20, 2009, when Squamee went OTJ. I am back, now, because Squamee has serious heath problems and may need insulin again---and I think of this as our insulin home. And even if she does not go back on the insulin, we are both suffering and I need you guys to talk to (Joanna,Sarah, Ele, Terri and Bebe were all invaluable to me last time around). So here is a summary of what has occurred, (excuse the length, or just skip it)

Sept 21, 2010.
A year and a half ago Squamee developed what looked like a jaw symptom. She would start eating and then move her jaw around like she was trying to dislodge something stuck in her mouth, while pawing at the sides of her face. There was also a slight clicking noise. She would stop eating and return again a few minutes later. Sometimes she would then be able to eat. She was put on long acting steroids which resolved the problem and she developed diabetes. She was on insulin (PZI) for several months and then went OTJ on Aug 20 2009. This August (2010) the jaw symptom returned. It did not respond to oral medicam. My vet thought it might be a tooth or TMJ. I took her to a dental specialist who could find nothing amiss on oral examination, but with x-rays found a badly rotten tooth which was extracted on Sept 7. That night she was able to eat more freely (anaesthesia?) and in the following days was on buprenex, but the difficulty eating got worse.. Gave injections of Medicam and Buprenex which seemed to help for a short while. Then did x-rays of skull to look for bone spurs(?) and also sonogram of stomach which showed nothing. Said the next step would be endoscopy and if that showed nothing, a cat scan. These were with the idea that perhaps there was some form of cancer. On Sept 17 she had a seizure, which the vet believes is the result of a brain tumor, which would also account for the mouth problem. If we are willing to consider brain surgery, a cat scan is now in order. The scan would be $1000 and the surgery in the area of $5000. (and we have already spent several thousand). I am not in a position to do this, much as it breaks my heart.
So at the moment, I am testing her BG daily, and the vet says if it stabilizes in the mid 300’s he will put her on insulin. He doesn’t want to do it at lower numbers because low blood sugar increases the likelihood of seizures. At the moment she is staying in the mid to upper 200’s. He says if the seizures become frequent, he can try giving her phenobarbitol. Currently, she is able to eat, although I do see just a little of the mouth symptom. She sleeps a lot, and doesn’t really seem herself.

I don't know how to tell if she is in pain. I am listening and watching all the time for signs of a seizure (last time she fell over, and was all wet from her urine), and she does not appear to have had another. (although if it were at night or when I am at work, I don't know if it would be apparent to me when I saw her). I have it in my mind that eventually this will become intolerable and I will have to have her euthanized. I have no idea if the time frame is weeks, months or more. It kills me to have to keep guessing about how she feels and if she is in pain.
 
Hi Judy,

Welcome home. I'm very sorry to hear the news.

Pain:
I am currently dealing with the pain question in H's brother. With H's brother we are struggling with the question of what kind of life is a "good" life for him. No easy answers for sure. I know with H that he would meatloaf. Hiding is common too. Lack of mobility/energy is common but can mean a million other things too. Cat's are generally thought to deal well with pain [not that they should] so I think it complicates knowing when they are in pain. I think the BGs going up are potentially a sign of at least "stress." When H was in super pancreatitis pain I [and my GF at the time] could literally see the pain in his eyes. One test can be to give pain meds like bup and see if there is any improvement. Too much pain meds in humans can make them nauseous, so I always start with 1/2 dose then add the other half and see if any improvement. You might want to read the recent TT topic on NSAIDs:
viewtopic.php?f=22&t=22322

No insulin:
Your vet knows you home test? Do you have the confidence in shooting for an intended nadir? What is right for most cats and DM may not be what is right for the average caregiver may not be what is right in your case. I'm no vet and I do not have the right answer to the question but I know that if it were my cat my heart would tug hard at me not to treat the DM. Hopefully you can get more input on this.

From what I hear, Cornell has a great vet school. Not sure if that would be an option for you [4 hours is not super close...].
 
Thanks for the welcome. Yes, my vet knows I home test. I do not know if I have the confidence to shoot for an intended nadir---on second thought, I guess not, since I don't really know what that means. I am a quick learner and very determined, so if you are interested in teaching me, I'd appreciate it! I guess I am wondering how it would feel to her---insulin vs. no insulin. When she was on insulin, she was not a very happy cat---spent considerably more time under the bed than she does now. She sleeps a lot now, but in an open, not hidden space. She is hungrier and thirstier than usual, but not nearly as bad as when she was originally diagnosed. (then I felt like she was starving, now I don't.)
 
I have a theory about hiding places: remove them. That means blocking all access to hiding places. Then they learn there is no hiding and that behavior stops. The chase game that always end in them losing ceases - then they can stop being the loser of their game and start being the winner of your love.

I'd also ask your vet about the "lower" BG that he is concerned about. Like how "low" is he talking/concerned about?

Looks like keytones might have shown up in the past. Have you been tracking those at all as her BGs have gone back up?

Shooting for nadir is basically looking at the history of your dosing and saying well, she went down X BG points on Y dose when her PS was Z, so in theory I *should* be able to expect that again. The amount they go down [or the delta - change from PS to nadir] at a given dose will probably change as the PS changes. So you can not automatically think that the delta on Y dose at a PS of 250 will be the same delta on a dose of Y at a PS of 150. This is probably making little sense lol. Generally one is not *supposed to* shoot for nadir, but I know it was certainly in my mind a lot and shaped the way I dosed. And I don't think there is a way to do it unless you are shooting on some sort of variable dosing [and/or sliding scale] type dosing.
 
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