Jay said:
But he looks so go in blue!!! Just kidding.
thanks by the way.
A few questions..maybe a PM from you ould be better (your call)
Why would that drop yesterday be of concern? (now I can figure out how this insulin works, almost real time as opposed to reading about it)
A few questions.
We all crashed out last nite at +2, at 260, although there are no stats beyond that, even if he did go Blue somewhere in the PM cycle, why then back up at the end of the cycle to over 300. I was told that Lantus can give us some duration, which as I interpret that to mean that he can hang at a lower number, late in the cycle, until that dose peters out.
Also I noticed that very late in his PM Cycles the past 2 days he dropped overnite. Do you attribute that to HC, and possible over dosing on Monday and Tuesday?
The high numbers appear to be rebound and dose settling to me. Late drops are indications that it's taking a whole cycle to clear rebound, which is totally normal in the beginning.
There's no way to analyze what's happening right now. The only thing we can see in early days of lantus use is whether the cat is beginning to respond to Lantus, and he very clearly is responding. When dosing with lantus *in the beginning* you have to always remember the liver is in play. With pzi the liver response is almost instant, with lantus, the liver response is a bit slower.. and lasts longer. As soon as his liver stops overreacting, you'll have much flatter cycles, but the mere fact that he went into blue AT ALL on your first dose is your clue that when rebound starts clearing, you could already be very close to your maintenance (ie: good) dose.
You don't have dose peter with lantus like you do pzi. Think about it like this: at every point during his cycle, including +12, Lantus is still working. With PZI, when it was done, it was done. There was no "layering" of doses. Rebound numbers put big strain on Lantus, so that's why it's so hard to hold your dose when you see numbers like that, but even though it is straining the insulin, it is not totally eradicating it, as would happen with PZI, so since it *is* layering, you must be extremely careful with your increases. It often takes days to see a full response to a dose increase.
As the dose settles, and Frankie learns how to use the lantus, you will find strange things like later nadirs, earlier nadirs, and sometimes no nadir. Periodically you might even see an inverted curve. The trick is to not look at the individual numbers. You look at the whole group of cycles together. "You can't see the forest for the tree" is exactly what happens with Lantus. Don't look at the tree, look at the forest. Your forest is still growing, so you can't quite see it yet, but it's coming

Short story: don't try to overanalyze right now, your head will explode. There's nothing you can make sense of when they are in the beginning days as the changing cycles are only a reflection of the cat learning to use the insulin provided.
Hope that helps, I'm bad at explaining what's in my head. Gotta run, but I hope others can take up where I left off