Dosing After Hypo

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LisaslzyS

Member Since 2012
My cat Mandy had her first hypo event last night. When I tested her at +4 her glucose was 36. I tried to bring her up with canned food which she devoured, but after 45 minutes and a further drop to 30, I administered karo syrup with more food. She did not have a lot of symptoms other than hunger. Her numbers started to rise after the syrup.

Her readings today have been over 400, but mostly in the 300's. I've given her two reduced doses of insulin about six hours apart because I don't want her numbers to drop too low. What is the normal dosing following a hypo? How long will it take her to get back to normal? She is on bcp pzi.
 
Normal dosing is to do every 12 hours, as usual, sometimes with a reduced dose if they test lowish, as they may be more sensitive to insulin after a hypo.

The high you are seeing is due to having gone so low; she is 'bouncing' due to the kickback of compensatory hormones releasing glycogen, a form of stored sugar.

We have a specific protocol for managing low numbers/hypo situations, linked in the following glucose reference ranges
Here are some glucose reference ranges used for decision making using glucometers. Human glucometer numbers are given first. Numbers in parentheses are for non-US meters. Numbers in curly braces are estimates for an AlphaTrak.

< 40 mg/dL (2.2 mmol/L) {< 70 mg/dL for an AlphaTrak}
- Treat as if HYPO if on insulin
- At nadir (lowest point between shots) in a long term diabetic (more than a year), may earn a reduction.

< 50 mg/dL (2.8 mmol/L) {< 80 mg/dL for an AlphaTrak}
- If before nadir, steer with food, ie, give modest amounts of medium carb food to keep from going below 50 (2.8).
- At nadir, often indicates dose reduction is earned.

50 - 130 mg/dL (2.8 - 7.2 mmol/L) {80 - 160 mg/dL for an AlphaTrak}
- On insulin - great control when following a tight regulation protocol.
- Off insulin - normal numbers.
(May even go as low as the upper 30s (1.7 mmol/L){60s for an AlphaTrak}; if not on insulin, this can be safe.

= 150 mg/dL (8.3 mmol/L) {> 180 mg/dL for an AlphaTrak}
- the lowest level pre-shot for ProZinc, PZI, or other non-depot insulins.

> 150 mg/dL (8.3 mmol/L) {> 180 mg/dL for an AlphaTrak}
- At nadir, indicates a dose increase may be needed when following a tight regulation protocol.

200 mg/dL (11.1 mmol/L) {230 mg/dL for an AlphaTrak}
- no shot level for beginners; may slowly reduce to 150 mg/dL (8.3 mmol/L) {180 mg/dL} for long-acting insulins (Lantus, Levemir, and ProZinc) as data collection shows it is safe

180 - 280 mg/dL (10 - 15.6 mmol/L) {may be 210 - 310 mg/dL for an AlphaTrak}
- Any time - The renal threshold (depending on data source and cat's renal function) where glucose spills into the urine.
- Test for ketones, glucose is too high.

>= 280 mg/dL (15.6 mmol/L) {may be >=310 mf/dL for an AlphaTrak}, if for most of the cycle between shots
- Uncontrolled diabetes and thus at risk for diabetic ketoacidosis and hepatic lipidosis
- Follow your insulin protocol for dose adjustments
- Test for ketones; if more than a trace level of ketones, go to vet ASAP.
 
I am glad you are home testing. The reason she is high now is her body is trying to protect itself after being too low. This is called a bounce and will pass and she will come back down.have you changed food recently?

How much insulin did you give her that caused the low numbers. And how much did you give her today and when? You will definately want to reduce the dose.

Wendy
 
The following is Mandy's history for the last couple days -

9/21/13
7:00AM....+11.75....217...0.5U
4:15PM....+9.25.....159
5:43PM....+10.75....158
8;15PM....+13.25....201

9/22/13
5:45AM....+9.5......289...1U
12:45PM...+7........138
3:45PM....+10.......258...1U
6:30PM....+2.75.....182
8:30PM....+4.75......87
9:30PM....+5.75......92
10:30PM...+6.75.....107

9/23/13
12:30AM...+8.75.....190...0.5U
9:30AM....+9........129
10:30AM...+10.......207...0.5U
6:30PM....+8........352...1.25U - not sure if prior shot was a fur shot, but this is what caused hypo
10:30PM...+4.........36
10:50PM...+4.25......36
11:05PM...+4.5.......30
11:30PM...+5.........71

9/24/13
12:15AM...+5.75.....111
2:45AM....+8.25.....274
5:20AM....+10.75....453...0.75U
8:00AM....+2.5......314
11:45AM...+6.25.....358...0.5U
2:30PM....+3.25.....315
5:30PM....+6.25.....274

She is really high today but I know it is abnormal and I am reluctant to dose too much after the scare yesterday.

Thank you for the feedback.

Lisa
 
I am confused.. what was the reason you gave 1.25? That was too much. If you have a fur shot, never ever reshoot because as you have discovered, some may have gone in.

Second you want to dose every 12 hours (give or take 30 minutes) because you dont want overlap in insulin.

Also I think she might be dropping lower in the cycle than you think - before changing her dose from 0.5 you might want to try and get more spot checks around +3 to +5.

What are you feeding her?

Wendy
 
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