diff. between tight and relaxed regulation?

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Do you mean the protocols? The Tight Regulation protocol is more aggressive and has you raising doses in small increments but faster than you would do on the Start Low Go Slow Protocol.

TR aims for getting the kitty in the 50-120 mg/dL range for the majority of time. The SLGS goal is to keep them under 200 but generally above 90.
 
With TR, you hold doses for less time -- usually 3 - 5 days depending on where the nadir is. Doses are decreased with a drop below 50. With SLGS, you hold each dose for a week and a dose reduction occurs with drops below 90. From looking at SSs on the Relaxed board, I tend to think that many people hold the doses for too long and there is greater risk for glucose toxicity to develop.

I think there's a misconception with regard to the SLGS/Relaxed Lantus approach. There are a number of people who will go to that forum believing that they don't need to test. More specifically, that they don't need to get mid-cycle tests. I also think that there's the misperception that in the TR forum, we're test crazy. We do like data but there's also a recognition that people need to work and have a social life but we do try to underscore that safety is paramount.

FWIW, there is no such term as "relaxed regulation." There was a term needed to describe what amounted to the "other" Lantus board. The relaxed forum is relatively new. There is no research that supports a relaxed approach or that supports the SLGS approach. SLGS was what was available before there was TR and it is not specific to Lantus. With TR, there is published research.
 
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