Cushings - skin problems

SusieQ_Lily

Member Since 2020
Hi Everyone,

Was hoping i could ask for some advice please?

Lily was diagnosed in January with pituitary cushings. She was put onto Trilostane and we explored having the surgery at RVC to remove. Unfortunately, an MRI scan showed that the tumour was not symmetrical and their is a major blood vessel running through the tumour. Surgery was deemed near impossible.

We've been managing fairly well, until recently where we have areas of scaly skin/dandruff. The flaky skin pulls the hair away. The skin left behind is either very pink or purple and then a wound develops. This heals but the hair never grows back. Before trilostane we had very fragile skin which tore easily, but her skin is very good now in terms of fragility. This is very different. We've had bacterial tests and the vets have said its a symptom of cushings and there's nothing they can do.

Her stim tests are all perfect, her diabetes is well managed, so we're struggling with why this is happening and there's nothing we can do.

I'll upload a couple of photos, does anyone have any experience with this? Thank you
 

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I'm sorry that I can't offer any information. I'll tag a couple of very knowledgeable cat people and see if they have any information that they can either share or steer you in a direction. Have you done a search on this website using Cushings as a key word? I have read that Cushings does cause some skin conditions but that is all I know. I wonder if the little sores cause scar tissues and that's why hair doesn't grow back?

@Wendy&Neko
@Marje and Gracie
 
Sorry, neither Marje nor I have experience with Cushing's kitties. We have had a couple of members try Trilostane with their cat, but neither have posted for at least a year.

I just have the links to a couple papers talking about treating cats with Trilostane. This one about a cat that went into diabetic remission and another abstract. Some of the authors of both papers were associated with the Royal Veterinary Clinic in England. They have a diabetes remission clinic you can email. They are quite responsive to questions and might be able to help. I only dealt with them on acromegaly though, the other kind of pituitary tumour.
 
Hi Everyone,

Was hoping i could ask for some advice please?

Lily was diagnosed in January with pituitary cushings. She was put onto Trilostane and we explored having the surgery at RVC to remove. Unfortunately, an MRI scan showed that the tumour was not symmetrical and their is a major blood vessel running through the tumour. Surgery was deemed near impossible.

We've been managing fairly well, until recently where we have areas of scaly skin/dandruff. The flaky skin pulls the hair away. The skin left behind is either very pink or purple and then a wound develops. This heals but the hair never grows back. Before trilostane we had very fragile skin which tore easily, but her skin is very good now in terms of fragility. This is very different. We've had bacterial tests and the vets have said its a symptom of cushings and there's nothing they can do.

Her stim tests are all perfect, her diabetes is well managed, so we're struggling with why this is happening and there's nothing we can do.

I'll upload a couple of photos, does anyone have any experience with this? Thank you
Hi, I am searching information about cushing in cats and their skin. Could I send you pics about the skin of my cat. I am from Argentina and I didn't get a diagnostic yet...
 
@Gabriela It would be best if you start your own post in this forum. In the mean time, take a look at the paper attached to this post here.

Sería mejor que inicie su propia publicación en este foro. Mientras tanto, eche un vistazo al documento adjunto a esta publicación aquí.
 
Sorry to resurrect an old thread (but there are so few on Cushing ;) ). I *may* have an explanation (disclaimer I’m not a vet). The excess cortisol of Cushings causes changes in some skin and blood vessel proteins. I’ve only found one study, and it was in humans, but they measured these in Cushings patients and controls at baseline and after one year of treatment and there was no significant improvement. Whether that means it takes longer, or never improves I don’t know. My first Cushing cat died during treatment so I can’t say what may have happened with his skin issues. My current one still has issues but he’s maxed out on Vetoryl and still has elevated cortisol. I read one anecdotal report of a cat post surgery who was improving in general but still needed to wear T shirts. Someone here has a cat whose surgery was successful but idk if their skin fragility improved. I suspect part of the problem may be these cats are often older, and at least in humans skin and blood vessels become more fragile with age even without underlying disease due to lost regenerative capability.
 
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