Re: Can't get my cat regulated. Need advice!!!!
Nic~n~Tom said:
Hello, I'm hoping someone can help me out. After several months, my poor cat's diabetes is still not regulated and his quality of life has gotten really poor. He is 9 years old, 15 pounds with a large frame. We started him on glargine (sp?) a few months ago and it didn't help his symptoms at all. He drinks massive amounts of water all the time and always has a huge bladder because of it. We started at 2 units of glargine, moved to 3 and then 4 a few weeks later and had no improvement. We then switched to Prozinc. We started at 2 and now we are at 6. We started doing home glucose curves a couple weeks ago and his numbers have never been below 525. It's usually around 600-700. It seems like the insulin doesn't do anything! A few other things to note... He has had urinalysis and urine cultures with nothing found. He had a test for pancreatitis which came back inconclusive, right between normal and too high (420 if I remember correctly). At one point, we bought a brand new vial of insulin,thinking that possibly there was something wrong with it. We've had several fructosamin tests done and they are always way high. He has developed neuropathy really bad and barely walks around anymore. He had an x-ray a couple days ago and nothing abnormal was found other than a huge bladder (most likely because he drinks so much and doesn't want to go to the litterbox). He always seems hungry and still eats well but he's slowly losing a little weight. I'm so frustrated and sad and just hope there is someone out there that may have some advice. Please let me know if you have any ideas of what we can do or what could be the cause of what seems to be a resistance to insulin. Thanks!
Well, you have come to the right place.... man, your story sounds familiar; I've heard it before a few times.
OK first thing is diet.
What are you feeding? Low carb wet food or raw is the way to help keep the BG numbers down.
Here are some links with info on foods. There are more links, but it's a start.
Binky’s Food Lists
Feeding Your Cat: Know The Basics of Feline Nutrition
Some cats are very carb sensitive and I have seen cats at high doses, but they were being fed all dry food, and once the diet was changed, down came their insulin needs. One of my own cats, Shadoe, if she got ahold of just a mouthful of dry food, her BG numbers could jump 100points or more.
So food's kind of important.
Next, is home testing. You are going to save yourself lots of money by testing at home and know exactly how your cat is doing. Numbers at the vet are often colored by stress so they're not of much use.
The fructosamine tests can be eliminated because it's just an average of your cat's BG over the last few weeks, and if you are home testing, you can get that average from your own meter.
If you are in the US, just pick up a Relion meter at the pharmacy as these meters have the most inexpensive test strips.
While you are getting a meter and test strips, that's if you are not already home testing, also pick up some KETOSTIX so you can test your cat's urine for ketones. I am thinking if you have not had any issues so far, with months of high BG numbers, your cat may likely not be ketone prone, but better safe than sorry and do the testing at home.
Testing on cat’s ear
Now, you were given some links on conditions for insulin resistance.
I have seen some people give their cat insulin up to a certain dose, then the owner and vet 'think' it's not working, so they switch to another insulin, and get the same problem..... one person tried 4 different insulins, and had the same problem.
The problem is that they just had not reached the good dose for their cat! Work your way up to say 6u and then switch to another insulin and start over lower .... well, what if your cat's good dose was 9units? You got close but stopped too soon!
YES, you can get your cat regulated, so don't worry about that.
Once you have confirmed the diet is low carb, and you start home testing and have numbers to show how your cat is doing, you can dig in and start to work towards the good dose for your cat.
Regarding insulins, I would suggest you try Levemir. I know that Lantus is a good insulin, and for some cats, PZI is also a good insulin, but PZI is more of an intermediate insulin with no overlap, and Lantus has been known to sting at higher doses (as per human diabetics), so if you do find that your cat is a high dose cat, you will find that Levemir is most suitable.
I have had 2 high dose cats, and one did much better on Levemir than Lantus, so I have seen the difference between the two insulins at high doses.
If you are already feeding raw or low carb wet, and you are home testing, then you talk it over with your vet about having two tests done for insulin resistance. Be sure to have both tests done because many cats have one or the other or both.
One of mine has just acromegaly, the other, Oliver tested positive for both acromegaly and IAA.
IAA Test
IGF-1 (Acro) Test
You can get plenty of help on this site to sort out your cat's issues.
most people keep track of their blood glucose test numbers in a Google spreadsheet as it's free and you can set up access for others to view the numbers and they can give you a hand, some suggestions where to go on the dosing.
Create your Spreadsheet
Now, whatever you do, if you don't need to change the food much, don't let people tell you that you must start over at 1unit am and pm; you have already done that a few times, so once you are testing and have some numbers, and then decide on what insulin you will use, you can get yourself on the road to the good dose for your cat.
You mentioned that you are doing some curves; if you are doing these at home, maybe you can post the numbers in here and also set up a spreadsheet.
Any questions you have, ask away. Someone will be able to help you get answers here.