Bonehead move, pens, questions and a short novella

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Audrey's Mom

Member Since 2014
It's soon 2 weeks since my Audrey was diagnosed diabetic and prescribed 1 unit of Levemir every 12 hours. She's a little trooper and still quite ravenous so she doesn't flinch at her shots while she's gorging on her 'new to her' FF Pate and/or Friskies Pate. The vet clinic had recommended and provided some Purina DM Savoury Selects, so that's all used up and we will not continue with that product, thanks to the good info here.

My boneheaded move this morning was injecting a bit of air into her vet supplied 3mL Levemir 100 U/mL 'Penfill' vial before drawing her insulin shot with a syringe. The air going in is apparently supposed to equal the same amount as the drawn insulin. I either hadn't fully awoken, had enough coffee, or had a brunette moment :o .

Before I knew it, I literally blew a gasket...the bottom stopper. I watched $43.00 of insulin seep into my palms, through my fingers and on the kitchen counter in what seemed like s-l-o-w-w-w motion. There was no insulin to be safely saved. I didn't think sucking it up with a turkey baster was a brilliant idea ohmygod_smile .

It's Sunday. Vet clinics are closed in our small City. There are emergency numbers, but I liken that to calling a plumber on a Sunday for an exploding hot water tank where they rub their hands together in glee in anticipation of writing up the overtime invoice. I needed to stay calm.

I called a few pharmacies when they opened at noon and most only sold 5 packs to my dismay. I really only needed one vial right now. Lucking out at one major pharmacy, I found they do sell the vials separately and an exact replacement for the one I lost would be $22.00. Jackpot!

Mr. Pharmy looked after me himself. He said the Levemir 'Penfill' vial goes together with a NovoPen 4 just like bread and butter, Sonny and Cher or a horse and carriage. "It's so much easier!", Pharmy assured me. "The pen is free! You just have to purchase the needle inserts", he proudly announced. Just as I have recently been warned about 'Free' glucose meters that use expensive strips or my experiences with $39.99 computer printers using $70.00 ink, I warily asked Pharmy how much a 100 box of needle inserts will run. "Why, they're about the same price as the BD U-100 Insulin syringes your vet gave you a few of", he replied. He then took the time to give me a demo of the NovoPen 4 and I was on board.

The NovoPen 4 comes with some individual starter needles that look like Barbie doll Keurig cups, but Pharmy and I agreed that the very short, 4 mm included needles could be problematic in giving my furry beast her shot. He suggested a longer one and I totally agreed. After rooting through his needle den, he produced a box of BD Ultra-Fine Pen Needles that are 8 mm, 31 Gauge and compatible with the insulin pen. They're not quite as long as my syringe needles, but for the same price, I was willing to give these a shot (no pun intended).

I was quite excited about our new fandangled pen. When home and upon googling and searching, I found very little about this particular pen here or anywhere else for the specific use with felines. Audrey duly missed her morning shot which was a rare occurrence. I was a little nervous to try the pen shot this evening, so out came the syringe - I still have a few left from the vet. Maybe the pen isn't that common with pets, as it only dispenses 1 unit increments - no half increments. This works for Audrey right now, but maybe not in the future for any .5's.

If anyone uses these pens, does the Levemir vial still have to be rolled in the hands before administering? This would mean removing the cartridge from the pen before each shot. The vet clinician insisted the vial be rolled in the hands with the syringe method. According to Levemir Penfill facts, "it is not necessary to shake or rotate the vial before use". The vet office also insisted on refrigeration at all times, whereas the Levemir penfill fact sheet says it's can be kept for up to 42 days at room temperature. Perhaps it can be used that much longer with refrigeration? The vet office told me to use it for about 3 months before replacing it with a new vial whether there's any left or not.

I came home and being curious, I tried 1 unit test shots on a piece of paper with the regular syringe as well as the new pen, as I was nervous the dispensed amount would be different or inaccurate. I'm such an overthinker...sheesh. The amounts looked the same on paper. Lol. We are heading out of the country in a few days for a week and family/friend cat sitters will be using the 'much easier' pen as beginners (like myself) to the world of insulin for pets. I'm a stickler for detailed direction when it comes to my lovey and part of the attractive feature of the pen is the ease for my sitters to just dial it to 1 and administer the dose while Audrey pigs out.

I'd sure like to know more about insulin pens, recommended needle lengths/gauges and their reliability in general. And the discrepancy between 'rolling in the hands' and refrigeration advice.

I would also like to give a high five for anyone who is still reading my novella. I'm usually just a mild head-case, but still not quite over the nerves of this whole new world. nailbite_smile

Cheers!
Diane
 
We treat the pens like little vials and use a syringe to withdraw the insulin from the pen. Pens don't let you do 0.25 unit increments which we may need for our tiny cats.

U-100 3/10 cc (mL), short or long needle, 30-31 gauge syringes work just fine for this.

No need to roll the Levemir; there is nothing to be mixed.

Refrigerated, Levemir may be used up to 6 months or so before pooping out. It was tested for humans up to around 45 days, so that is all the pharmacist can say.
 
Good thing you managed to get a single pen on short notice. :-D We have a post on handling and storage of Levemir (and Lantus) here, including a video showing how to draw from pens or vials.

People have different preferences for needle lengths on the syringes. It may vary depending on whether your cat has long or shorter hair. I like the 31 gauge needles as my cat doesn't really notice them.
 
The problem with using the pen with the pen needles is that most pens only dose in 1 unit increments. However, some pens dose in 1/2 unit increments but I do not remember which one do.
Very frequently smaller increments are required.
Also. with using the pen with the needles yo have to keep the needle in the cat for 6 seconds or so after yu depress the button. That can be hard at times. If you do not keep it in long enough a full dose is not given and you can see a drop or so of insulin come out of the needle after you pull it from the cats.

I use the Levemir disposable pen for my MurrFee. However, he is on 18 units so a drop of so of a missed dose is not important.
 
With the pens and the pen insets for Levemir you don't shoot air back in to the pen. The stopper will slide down on it's own as that is how they are designed to work.

Mel and The Fur Gang
 
Thank you all very much for your responses. What a great bunch you are, and the information here is so great!

I have learned that the terms vial and a cartridge are different animals. I have been calling my cartridge (penfill) a vial. Now I know the difference. The first insulin given to me by the vet was just the individual penfill cartridge and syringes. I blew out the rubber bottom of a single cartridge due to stupidity! :?

I have also learned in general from a human diabetic point of view, the question as to whether to refrigerate or not to refrigerate opened and in-use Levemir has a highly varied response for personal or medical advice reasons. Some still refrigerate their in-use insulin out of habit, some don't enjoy a cold shot that can sting or burn - others don't feel it, some don't keep it cold as they use theirs at a fast pace, some do as they were told to from their medical advisor. Some love pens, some like the syringe - cartridge/vial method. So much variation and opinion on this out there! I will not refrigerate the insulin, nor will I roll it as the vet clinic mentioned.

I have learned from my NovoPen 4 manual and other's experiences that refrigerating the pen device is not at all recommended (possible mechanism/battery/condensation issues?).

I've decided that since reading up here and everywhere on Levemir, NovoPen 4 and watching youtube until my eyes were bleeding and the fact that I can pick up my single cartridges anytime from the pharmacy for approximately $22.00 Cdn., even if I follow the manufacturer's recommendation strictly for 42 days kept at room temperature, it's inexpensive enough to replace with a fresh penfill cartridge if I go by the book (that's another point of debate out there, for sure). There's way more than enough in that cartridge as well to prime the pen before each use.

I'll keep the pen out of the fridge in it's storage case at room temperature. This morning, Audrey responded no differently to the new pen injection, the 8mm/31 gauge needle worked out just fine, and she is so distracted when she eats, that holding the injection in for at least 6 seconds was no problem for her. Good kitty!

I'll go over the pen injection instructions, as well as syringe/cartridge method with my caregivers should the pen fail for any reason. For now and while Audrey is on 1 unit, I'm very much liking how the pen performed this morning. Time will tell. If Audrey's dose ever includes part increments, I shall go back to the syringe.

Thanks for putting up with me. :YMSIGH:

Cheers!
Diane
 
Which store sold you the individual cartridge? As I'm in Canada too, just wondering if there's a store near me that will do the same.

We recommend keeping insulin in the fridge. It will last longer that way. Human diabetics (and high condition cats) will use up a cartridge that is out of the fridge before the manufacturers recommended time. I've gotten over 70 days from a Levemir cartridge. I use a syringe, and I just hold the syringe with insulin in it between my fingers for a part minute to warm up the insulin before injecting. It's a small amount so doesn't take long.

Cats are sensitive to small changes in insulin. We usually change doses in .25U increments/decrements. You are fine on 1 unit for now to use the pen tips, but will have to go to syringes if the dose needs to change.
 
We all hear keep our in-use, as well as un-punctured pens in the fridge. In the USA pen cartridges are not sold, just the disposable pens as well as 10 ml vials of Levemir and Lantus.
What I surmise is that keeping an in-use pen in the fridge my results in some air being drawn in because of the temperature changes. Any air in the pen will effect the dose of insulin injected.
 
Thanks for your all of these thoughts. I guess it's not really that big of a deal for me to refrigerate just the cartridge and slip it into the unrefrigerated pen before each shot. I do know I prefer the pen itself to stay out of the fridge for optimal performance and from other's accounts. It all just becomes a routine really and one that's easy to get used to.

Wendy, I picked up the single 3 mL penfill cartridge of Levemir at my local Real Canadian Superstore Pharmacy for $22.35 pre-tax. The Pharmacist agreed it's not always done by certain pharmacies, but here they will break up the 5 pack for individual sale.

At the risk of going off topic, I am going to PM you Wendy about any information regarding best value with Blood Glucose Meters available in Canada (No ReliOn's here) if you know.

:smile:
 
Hi Audrey's Mom,
I am a beginner, two hours a beginner. I suspect that at least one of the triplets born July 2013 is a diabetic and has been from the beginning but it is only been a red flag for the past couple of days because of frequent visits to pee with minimal success. First step for me was removing the kibble and leaving the low carb wet food this morning and second is to get a blood sample. There was excellent info on how to obtain a sample on the website.Can you tell me if the blood glucose reading range for felines is the same for humans, i.e. between 5.0 and 7.0?
I live in Toronto, Canada. Where in Canada are you?
Regards, Jane aka Cassie, Beauty and Pixie's mom
 
Glucose numbers for normal cats are from about 40 mg/dL to 120 mg/dL on a human glucometer.
For diabetics, we like them to remain above 50 mg/dL for safety and have as good controll as possible otherwise.

See my signature link Glucometer Notes for more details.

Welcome, Jane - please start a New Topic introducing yourself to the board when you get a chance.
 
johndm@rogers.com said:
Hi Audrey's Mom,
I am a beginner, two hours a beginner. I suspect that at least one of the triplets born July 2013 is a diabetic and has been from the beginning but it is only been a red flag for the past couple of days because of frequent visits to pee with minimal success. First step for me was removing the kibble and leaving the low carb wet food this morning and second is to get a blood sample. There was excellent info on how to obtain a sample on the website.Can you tell me if the blood glucose reading range for felines is the same for humans, i.e. between 5.0 and 7.0?
I live in Toronto, Canada. Where in Canada are you?
Regards, Jane aka Cassie, Beauty and Pixie's mom

Thanks BJM
BJM is right, Jane. If you start a new thread, you'll find your questions won't get lost. I can't help you much as I am a newbie as well and still learning. Welcome, though!
 
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