B12 liquid form

Status
Not open for further replies.

Mocha aka Cold Play

Member Since 2015
I am wondering about any benefit of B12 For Cats liquid, it claim is natural, bioavailable, non-synthetic vitamin in liquid form and supports the health of your cat’s immune system, nervous system, digestive system & cognitive function.

I have 2 older cats, one has sarcoma but it is being held at bay with chemotherapy pills. I am wondering about the benefit mostly to help with energy for both and reduce arthritis, and one has more anxiety issues with weather. Has anyone had any benefit with this. I will ask the vet next time I see her but that will be many months. It is very costly so if it helps that is ok. Does anyone have any experience with it?
 
B12 is not typically used to treat arthritis. B vitamins are sometimes lower in cats that have GI absorption issues and methyl-B12 is helpful for neuropathy. I've not seen any info on an oral, liquid version.
 
I give both my CKD cats mehtyl-B12 but is more to help with nutrition and appetite and it has worked just fine, I've seen some information mentioning it may help mobility and arthritis but not really formal studies so I could not say it actually helps, and I have not seen a liquid oral version it usually comes in capsules
 
So the B-12 injections are for the IBD cat because IBD cats frequently have problems absorbing B-12 from their food. The Zobaline was for the diabetic cat. I also currently give my cat, Ginger, little capsules of Jarrow B-Right B-Complex. I take the human capsule and split it into 10 number 4 size capsules and she gets one every night (with her Clopidogrel blood thinner in the same capsule.) That is to keep her hematocrit up. It works. Whenever I have gotten lazy and stopped making the capsules, her HCT dropped. When I give her the capsules, her HCT rises back up into an acceptable level (although still on the low end of the reference range.) B-Complex is extremely important for cats with kidney disease, and this is when I first started using it years ago in a CKD cat to raise HCT.

There is also a liquid form of B-Complex and also B-12. Is that what you've been looking at? Here's a link to one brand:
https://www.chewy.com/rx-vitamins-rx-b12-liquid-digestive/dp/192788
and the B-Complex, amino acids, potassium and iron:
https://www.chewy.com/rx-vitamins-amino-b-plex-liquid/dp/192737

Then there's good old Pet Tinic that's been around for a long time and has some various B vitamins in it as well as Iron, Copper.

Some of these liquid supplements may contain forms of sugar so you would not want to use them with your diabetic cat.

I've never heard of it helping for arthritis before. There are other supplements that probably would be better for that (Cosequin comes to mind, if Solensia injections or Adequan injections are outside of your budget -- also MSM or Turmeric are anti-inflammatory.) I'm sorry that your kitty has sarcoma.
 
You mentioned that one of your cats has sarcoma -- so I am copying and pasting a section on B-12 and cancer in cats. You may not want to supplement that particular kitty until you read this and decide first (or check blood first to see if he/she is deficient in B-12.) There's information on both sides of the issue. I will also link the entire B Vitamin pages from the feline crf.org site here. It goes over every type of B vitamin and it's use in the body, forms of B vitamins (liquid, injections, etc.) and more!
http://felinecrf.org/vitamin_b.htm#methylcobalamin

Vitamin B12 and Cancer

Hypercobalaminaemia is associated with hepatic and neoplastic disease in cats: a cross sectional study(2014) Trehy MR, German AJ, Silvestrini P, Serrano G & Batchelor DJ BMC Veterinary Research 10 pp175 looked at elevated cobalamin levels in cats who had not received vitamin B supplementation and states "The current study has suggested possible associations between hypercobalaminaemia and the presence of either solid neoplasia or liver disease in cats."

It may be wiser not to give vitamin B12 to a cat with cancer because cancer cells rely on vitamin B12 for growth, according to Immunohistochemical quantification of the cobalamin transport protein, cell surface receptor and Ki-67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues(2015) Sysel AM, Valli VE & Bauer JA Oncotarget 6 pp2331-2348, which states "Cancer cells have an obligate need for cobalamin (vitamin B12) to enable DNA synthesis necessary for cellular replication."

Purina Pro Club Update (2013) 12(1) Dr Sysel of the Bauer Research Foundation states "Vitamin B12 is important in DNA synthesis, as cells cannot divide without it. Rapidly growing tumors that are actively dividing have an especially high demand for vitamin B12. Tumor cells produce TCII [transcobalamin, a protein which moves vitamin B12 through the bloodstream] to obtain all the vitamin B12 they can."

However, researchers are also looking into whether they can use cancer cells' need for vitamin B12 to target cancer. Immunohistochemical quantification of the cobalamin transport protein, cell surface receptor and Ki-67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues(2015) Sysel AM, Valli VE & Bauer JA Oncotarget 6 pp2331-2348 adds "The potential to utilize these proteins as biomarkers to identify neoplastic tissues, streamline therapeutic options, evaluate response to anti-tumor therapy and monitor for recurrent disease has important implications in the advancement of cancer management for both human and companion animal patients."

A stability-indicating HPLC method for the determination of nitrosylcobalamin (NO-Cbl), a novel Vitamin B12 analog (2014) Dunphy MJ, Sysel AM, Lupica JA, Griffith K, Sherrod T & Bauer JA Chromatographia 77(7-8) pp 581-589 reports further on the use of nitrosylcobalamin "as a biologic ‘Trojan horse’, utilizing the vitamin B12 transcobalamin II transport protein and cell surface receptor to specifically target cancer cells."

University of Pennsylvania School of Veterinary Medicine has been researching whether cats with lymphoma might actually have a vitamin B12 deficiency (which is quite possible, because lymphoma may reduce vitamin B12 absorption in the intestines), and if they do, they plan to offer supplemental treatment to address the deficiency.
 
I saw an ad by Jackson Galaxy for the b12 liquid. This is why I was curious as to the benefit. I was wondering if Cosequin is just a better option for arthritis. The older cat jumps fine UP but comes down from a bed or chair sliding on the side of the furniture to ease the landing. And, sometimes walks with a variation in her stride mostly when barometric pressure is on the rise and I have more pain myself.

Thank you for the kindness about sarcoma. I have learned something new with each cat. I no longer have Mocha (pictured in my profile) that brought me here. That has left a hole forever. Looks like someone removed access for me to upload a photo oddly of the cat that now has sarcoma. She is a calico. She was adopted at the age of 10 from a shelter because the remaining cat after Mocha passed was not doing well for many months. Callie (sarcoma) has been the perfect friend for her and got her out of the depression. So, I hope to keep Callie healthy as long as possible. We tried to find a younger cat for her but the personalities were not going to be a hit like Callie clearly is.



There are other supplements that probably would be better for that (Cosequin comes to mind, if Solensia injections or Adequan injections are outside of your budget -- also MSM or Turmeric are anti-inflammatory.) I'm sorry that your kitty has sarcoma.
 
One of my kitties (Gizmo) was having early signs of arthritis. At my vet's suggestion, I started him on Cosequin. He's had a great response! He's a big cat (a solid 14 lbs of Norwegian Forest Cat) and gets 2 capsules/day.
 
Status
Not open for further replies.
Back
Top