A miracle. In remission after a year .

TheDudeAbides

Member Since 2025
Dear All

I hope this post helps at least one person. That’s why I am writing it.

My gorgeous cat was diagnosed with diabetes in August 2025. Initially she was on Caninsulin starting at 2 units twice a day. Her weight still kept dropping and her water intake was out of control even though we increased her dose by one unit ( half twice a day ) each week.she went down from 5kgs to 3.7 . I then insisted they move her on to Prozinc. At the time she was on 5.5 units of caninsulin twice a day.,she started prozinc at two units twice a day. We increased at one unit each week .( half a unit twice daily ) . Her weight continued to decline but the pace slowed . Finally , after many months she stabilised at seven units twice a day .she stabilised after we added metacam once a day( non steroidal anti inflammatory ) to her medicines. The pain from the arthritis was preventing her from responding to the insulin .a few months later we started her on monthly injections of Solensia to help with her arthritis pain. After a couple of months from monitoring her clinical signs it became apparent we could reduce her insulin. We decreased at one unit each week and got her down to 5 units twice a day .continued on this dose for a few months. I explored surgery toremo e her pituitary tumour ( the acromegaly)and decided it would be too traumatic and risky for my baby girl. We then decided we had nothing to lose by trying her on cabergoline( it counters the effects of the excess growth hormone which causes insulin resistance and also pain from worsening arthritis caused by joints growing etc ). She responded brilliantly. We gradually reduced her insulin by one unit weekly . I am writing this for you as this is potentially the last week my baby will require insulin. As of today she is down to half a unit of insulin twice daily. All been well next Sunday she comes off the insulin. Dudes it’s a total miracle. She has started playing again with me and has much more energy . Her loving behaviour and cuddles have all returned .her hunger is not manic any longer . She weighs 4.7 which is a bit high and once she comes off the insulin I will reduce her food intake gradually until she gets to 4.4 kgs.she is sleeping much better and no longer screeches all night. She has started exploring the garden and hanging out watching life again . She is visibly enjoying her life again . I am so over the moon. She is such a champion . She did not give up.she tried her best as did I .Countless vet visits . Also wonderful email and phone support from the team at RVC as well as the most amazing support and care from my local vet . I prayed my sweetheart would stabilise so we could share a few more years tigether .right now things are looking promising. I adore my cat . After a full year it seems we have got her totally in remission . Bless you all and I hope this helps at least one other kitty in giving you some ideas as well an appreciation of how patience and perseverance can pay off . It’s taken a year . Don’t give up on your little kitties. Feel free to message me with any questions. All the best . E
 
Hello, I am so happy for you and your girl. It's great that RVC was able to help. Were they the ones to suggest cabergoline? I've interacted with them via email, and they've been very helpful to me to, even though not a client. Great folks there.

We've seen several other acrokitties here go into remission with cabergoline. For the rest, they at least go to lower insulin doses and see improvement in their acro symptoms. It's nice to have more success stories to point to.

Was the cabergoline daily or every other day?
 
Hello, I am so happy for you and your girl. It's great that RVC was able to help. Were they the ones to suggest cabergoline? I've interacted with them via email, and they've been very helpful to me to, even though not a client. Great folks there.

We've seen several other acrokitties here go into remission with cabergoline. For the rest, they at least go to lower insulin doses and see improvement in their acro symptoms. It's nice to have more success stories to point to.

Was the cabergoline daily or every other day?
Hi .thanks so much. Initially she got 0.9 ml every second day .That worked well . The we tried 0.9m every day and that did not work at all well. So reverted to alternate days and it’s worked a miracle. The key is patience . Every slow change needs to be given plenty time to work, poppy started cabergoline at the end of April 2026. It’s taken from then to now to get down from 5 units of prozinc twice daily to 0.5. Twice daily . Next Sunday all been well she comes off insulin for the first time since been diagnosed in August 2025. It’s an absolute miracle . Am so happy .
 
Hi .thanks so much. Initially she got 0.9 ml every second day .That worked well . The we tried 0.9m every day and that did not work at all well. So reverted to alternate days and it’s worked a miracle. The key is patience . Every slow change needs to be given plenty time to work, poppy started cabergoline at the end of April 2026. It’s taken from then to now to get down from 5 units of prozinc twice daily to 0.5. Twice daily . Next Sunday all been well she comes off insulin for the first time since been diagnosed in August 2025. It’s an absolute miracle . Am so happy .
Cabergoline was suggested by RVC and confirmed by my wonderful local vet
 
I am really happy to hear that Cabergoline has helped your baby so much! My cat certainly had great improvements in BG on Cabergoline.

What is her blood glucose level now?
 
I am really happy to hear that Cabergoline has helped your baby so much! My cat certainly had great improvements in BG on Cabergoline.

What is her blood glucose level now?
Thanks 😀. Not sure as our focus has been on monitoring clinical symptoms rather than BG monitoring . Daily weight and water charts . Urine dipstick once a week to see if any glucose in urine and whether a lot or a little. Also monitor early hypo symptoms such as lethargy, staring into space , excessive howling . I have learnt to read poppy like a book. On occasion have done blood test at vet to check my conclusions and they are always backed up .
 
For anyone else reading and thinking about trying Cabergoline for your acrocat, we STRONGLY recommend testing blood sugars. And testing even more than you are used to. How fast Cabergoline works in a cat varies a lot. I've seen a couple kitties go from around 8-10 units to nothing in less than two weeks. Without monitoring, those cat's would have overdosed and hypoed. New to Cabergoline Jackson, has gone from 15 units to 9 in a month. Which is down in a month more than Poppy has done over 3 months. Poppy seems to be lucky that she is a cat that responded more gradually. Many other conditions can cause lethargy, staring into space or howling (such as hyperthyroidism). Symptoms of hypos in this post: How to treat HYPOS - THEY CAN KILL! Print this Out!!

My girl occasionally showed absolutely no symptoms in the 30's (less than 2 for mmol/L), one time sleeping soundly. :eek:
 

For anyone else reading and thinking about trying Cabergoline for your acrocat, we STRONGLY recommend testing blood sugars. And testing even more than you are used to. How fast Cabergoline works in a cat varies a lot. I've seen a couple kitties go from around 8-10 units to nothing in less than two weeks. Without monitoring, those cat's would have overdosed and hypoed. New to Cabergoline Jackson, has gone from 15 units to 9 in a month. Which is down in a month more than Poppy has done over 3 months. Poppy seems to be lucky that she is a cat that responded more gradually. Many other conditions can cause lethargy, staring into space or howling (such as hyperthyroidism). Symptoms of hypos in this post: How to treat HYPOS - THEY CAN KILL! Print this Out!!

My girl occasionally showed absolutely no symptoms in the 30's (less than 2 for mmol/L), one time sleeping soundly. :eek:
When Poppy started on Cabergoline she wore a freestyle libre glucose monitor for the first two weeks. Changed it every few days if it fell off .
 
And from this I learnt to align her behaviour and clinical observations with the readings . They confirmed what I had expected.
 
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