7/23 Cooper AMPS 85, +2 80, +8 90, PMPS 99, +2 86, +3 82

JL & Cooper

JL & Cooper

Active Member
Yesterday

It’s not urgent, so I’m not adding a ? prefix, but reposting my Q from last night, since I know it was past bedtime for most:

Numbers look good but curious… Hypothetically, if he were to go into remission while continuing in these numbers (85-95ish) is there risk of him coming out of remission faster than if he were staying lower (ex. 65-75)? I guess I’m wondering if there’s a correlation between how “green” numbers are and the strength of remission and/or successful healing of the pancreas? I’m extremely thankful/happy with how good he looks (numbers and otherwise), it just makes me nervous for long term success.
 
JL & Cooper said:
Yesterday

It’s not urgent, so I’m not adding a ? prefix, but reposting my Q from last night, since I know it was past bedtime for most:

Numbers look good but curious… Hypothetically, if he were to go into remission while continuing in these numbers (85-95ish) is there risk of him coming out of remission faster than if he were staying lower (ex. 65-75)? I guess I’m wondering if there’s a correlation between how “green” numbers are and the strength of remission and/or successful healing of the pancreas? I’m extremely thankful/happy with how good he looks (numbers and otherwise), it just makes me nervous for long term success.
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He looks great, Jenny.:bighug::D:bighug:
Let’s see if we can get you some answers from some of our amazing knowledge base
@Wendy&Neko @Sienne and Gabby (GA) @tiffmaxee
 
Have you ever read this post:
This is another good one: Journal of Veterinary Medicine, 2015:
Glycemic Status and Predictors of Relapse for Diabetic Cats in Remission

We don't actually know what Coopers normal fasting glucose concentration is, until he's actually off of insulin. Other factors that can cause a cat to fall out of remission, beside what is mentioned in that paper are infections/inflammation, such as needing a dental, urinary infections, pancreatitis, and other conditions such as uncontrolled hyperthyroidism. I wouldn't worry if he's 5-10 points above the recommended range is now. Remember, there is meter variance between BG meters too.
 
Wendy&Neko said:
Have you ever read this post:
This is another good one: Journal of Veterinary Medicine, 2015:
Glycemic Status and Predictors of Relapse for Diabetic Cats in Remission

We don't actually know what Coopers normal fasting glucose concentration is, until he's actually off of insulin. Other factors that can cause a cat to fall out of remission, beside what is mentioned in that paper are infections/inflammation, such as needing a dental, urinary infections, pancreatitis, and other conditions such as uncontrolled hyperthyroidism. I wouldn't worry if he's 5-10 points above the recommended range is now. Remember, there is meter variance between BG meters too.
Click to expand...

Thanks Wendy. Yes, I am familiar with both that link and the paper. My understanding of the paper is that the glucose predictors they discuss are outside of the “greens,” I believe they say >/= 135. Knowing that, I was more curious from board experience, if other patterns had been noticed. Especially as it relates to cats who come out of remission within the first 4-8 months after going OTJ- since that may point to a less strong reduction process, OTJ trial and remission to start with (higher numbers than preferred before a trial, taking faster reductions, not reducing below 0.25, etc). I know there are other factors when it comes to how long it’s possible for Cooper to stay off insulin, but wanted to make sure we were doing what we could now to prepare for a strong OTJ trial and hopeful remission, especially since he’s been earning reductions for staying <100, despite not spending much time <80.
Good point about his glucose concentration though, I’ll keep that in mind.
 
I've seen people try to rush the process to getting off of insulin, stopping at 0.5 units for example. But it can still take more than 4-8 months for that remission to fail. I've seen it said that taking reductions by a week in solid green is a good way for a strong remission. That's a lot of healing numbers with a little insulin support.

We do have a few current members whose cats came out of remission, some after quite some time. Might be worth taking a look at their spreadsheets and seeing if you can draw any conclusions.
 
I agree with Wendy. Taking the process more slowly makes sense. It's often the vets who are nervous about low numbers and suggest that people stop insulin prematurely (by our standards). There are always the unpredictable issues like the need for a dental that can throw a cat out of remission and there's no accounting for unpredictability.
 
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