5/3 Oberon PMPS 318, +3 266, +4.75 177

Lisa & Oberon

Lisa & Oberon

Member Since 2020
yesterday: https://www.felinediabetes.com/FDMB...-6-302-9-294-pmps-333-1-r-4-242-8-189.246890/

No greens overnight, so it's increase time!

Summer and Susie said:
Do you add the R when the insulin itself does not work as well as you hope? Or is there any reason?
Click to expand...

In Oberon's case (with IAA), R is used to supplement the high dose of Lantus to give me more flexibility, since his dose needs can change abruptly depending on what the anti-insulin antibodies are doing. I can't always wait for the Lantus depot to catch up. It's especially helpful since he also has a history of ketones. The rules I've set (only for Oberon; other people have different guidelines!) are to use R at preshot or midcycle if he's over 300, but not if he's already sliding down or just got a dose increase, or I can't monitor well during that cycle. There's a little more to it than that, but that's the idea.
 
Lisa & Oberon said:
yesterday: https://www.felinediabetes.com/FDMB...-6-302-9-294-pmps-333-1-r-4-242-8-189.246890/

No greens overnight, so it's increase time!



In Oberon's case (with IAA), R is used to supplement the high dose of Lantus to give me more flexibility, since his dose needs can change abruptly depending on what the anti-insulin antibodies are doing. I can't always wait for the Lantus depot to catch up. It's especially helpful since he also has a history of ketones. The rules I've set (only for Oberon; other people have different guidelines!) are to use R at preshot or midcycle if he's over 300, but not if he's already sliding down or just got a dose increase, or I can't monitor well during that cycle. There's a little more to it than that, but that's the idea.
Click to expand...
What is IAA?
 
Summer and Susie said:
What is IAA?
Click to expand...

Insulin autoantibodies. Basically, since the insulin we give is slightly different than actual feline insulin, some cats recognize it as "foreign" and mount an immune response against it. The antibodies bind to some of the insulin and prevent it from functioning. So cats with IAA need more insulin to get an actual response, but the antibody levels can fluctuate over time, so the dose needed to get past them also changes. Supposedly the antibodies fade after months to a year or so. I'm hoping that means this will only last a while longer for Oberon, but for now I just have to work with the numbers he gives me.
 
Lisa & Oberon said:
Insulin autoantibodies. Basically, since the insulin we give is slightly different than actual feline insulin, some cats recognize it as "foreign" and mount an immune response against it. The antibodies bind to some of the insulin and prevent it from functioning. So cats with IAA need more insulin to get an actual response, but the antibody levels can fluctuate over time, so the dose needed to get past them also changes. Supposedly the antibodies fade after months to a year or so. I'm hoping that means this will only last a while longer for Oberon, but for now I just have to work with the numbers he gives me.
Click to expand...
Just another mountain for you and Oberon to climb. Sorry to hear you and he have to deal with this too. I do hope that Oberon will adjust to the human insulin and lose the IAA.
 
And having said all that, I'm skipping R this evening, even though he's at 318. I'm really short on sleep (for non-cat reasons, for once) and I'm hoping to get to bed early. Naturally this means he'll probably dive tonight...
 
Morning numbers: AMPS 306 (dose increase), +3 351 (dude, really?), +6 356 (1 R), +9 306

One last check before bed, and he's plunging at ~50 points/hour. Figures.
 
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