Sienne, thanks for your direction. I completely trust your judgement and will follow your advice and raise Gus to 3U this PM. But, I need to tell you that I am afraid to do that. Gus was at 3U for 6 cycles back on 3/27. At this level, he started becoming lethargic and was limp as a rag. He acted withdrawn and was urinating at a ridiculous rate. I thought we were going to lose him and because of that, I went to 3.5 to counteract the HI #s. Of course, that just made things worse. I guess that I just need reassurance that going to 3U will be OK. Can you explain to me why that won't happen again? I really don't mean to be so high maintenance. Once burned, twice shy. The protocol is tried and true and I realize that to find his correct dose, I need to go up. nailbite_smile