This is where you have to learn what works for Toby. High dose kitties don't always play by the same rules as we like to be a bit more cautious and respect that larger depot. You could try taking a reduction, maybe .5 unit? Or 1 unit? With Neko, when she goes under 50 I give her a shave reduction, which is what .5 unit would be for Toby. He's been looking so good lately I wouldn't want to reduce too much. One possible tactic that Julie has suggested before is to give an even larger reduction after the low number to reduce the depot (1/2 to 2/3 of regular dose for just tonight), then come back tomorrow morning with his new dose. Tonight's reduction might not be necessary if he's really bouncing by PMPS.