Hello and welcome. I will try to answer your questions.
Yes, his body isn't used to that long stretch of yellows or numbers in the 200's that he saw last night. The other complicating factor could be something we call NDW or New Dose Wonkiness. More explanation in this post:
New Dose Wonkiness (NDW) and failed reductions
Could you please take a look to Kokkinoulis spreadsheet and assist me?
What sort of assistance are you looking for?
Did I make a mistake, was I in a hurry and increased the dose early when I should have kept the same dose for a few more days? Should I reduce to initial 2.5 unit?
Yes, you did increase too quickly. When starting Lantus, you are supposed to hold the starting dose for 5-7 days, to build the depot. So you increased to soon. Also, with nadirs below 300, you increase the dose by 0.25 after 6 consecutive cycles at a given dose. However, fur shots interrupt that count of cycles. More information here:
Reminder: Counting Cycles
Should you decrease the dose? I would not as you've already shot two doses of 2.75 units and his numbers are still fairly high, providing you can monitor closely the next few days. And after that, I would hold the 2.75 unit dose for at least 6 cycles. Unless he goes below 50 and earns a reduction.
Moreover, how many times a day and what exactly hours should I test my cat at home now? Today he was also very aggressive during the BG home tests and I finally measured his BG levels correctly after many attempts. I think I should feed her more because I made the mistake of having him on a diet at the same time as he is unregulated.
As for how many times per day to test, at a minimum you need the two preshot tests, plus at least one other per cycle for a total of 4 per day. Most of us following TR, tended to more tests. The more data you have, the easier it is to figure out the best times to test. Right now, it is early in Kokkinoulis Lantus journey. His body is still learning how to use the insulin and the best times to test may vary from cycle to cycle. Ideally you'd like to find what his onset and nadir times are. The nadir is the lowest point in the cycle and we determine how to change the dose based on those nadirs. Although a typical nadir is +6, it can vary by cat and even then from cycle to cycle. My cat's Lantus nadir was between +7 and +9, I've seen others at +3. Your job is to collect enough data to find out what is is for your cat.
- Onset - the length of time before insulin reaches the bloodstream & begins lowering blood glucose
- Peak/Nadir - the lowest point in the cycle
There is a guideline we use to determine when you might need more testing for a cycle, and that is based on how the +2 test compares to the preshot test. If the +2 is quite a bit lower than the preshot (like yesterday AM), that's a indication of a more active cycle that needs more testing. A +2 about the same as the preshot is a regular type Lantus cycle that will still have some downward movement. A +2 that is higher, like this morning, indicates a quiet cycle that will need less testing.
When your cat is in mostly higher numbers, finding the nadir will be more difficult, and the time might change when he gets closer to good numbers. Other facts can influence a nadir, such as breaking the bounce, which he was looking like he was doing yesterday morning.
How much food are you feeding now? Is he at an ideal weight or do you know how much he should weight? Unregulated cats might need more food, but I wouldn't overfeed as he's already a large cat. I got a pet scale and weighed my cat at least weekly. I'd use that and my goal of where I wanted her weight to be, to determine how much more or less I should feed.
