Peggy and Mickey (GA)
Very Active Member
OMG I am mystified...weird stuff here. Way worse than yesterday..
Why are we worse today>???
Why are we worse today>???
1/8 Mickey amps 342 +7 304 pmps 376! WHAT?
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Joanna & Bix (GA)
Very Active Member
Re: 1/8 Mickey amps 342 +7 304
If you have good results on cycle 1 of a dose, with a U-curve and a dip to a better-than-normal nadir, but then lose those results on cycle 2, my understanding & experience with PZI is that it means their body has overcome that dose. The cycle 1 result is the "wow factor", and then after they get over the "wow", they go "nah, not enough insulin". Someone (Rob?) described it once as like a drug addict - keep needing more to get the same insulin high. Of course other explanations are possible I suppose, and you don't know for certain what happened last night - for instance if he got a good nadir, today could be a pink reaction cycle. Given his history though (no known low nadirs, and signs of possible insulin resistance (?)), I would suspect there was no good nadir last night.
I would probably give it another cycle tonight on this dose, and if you can, get a nadir test. If no improvement, I'd consider raising again. I'd like to hear what others think though. Especially as you get into higher doses with not a lot of response, I start to feel out of my league. Have you ever tested him for insulin resistence? I don't think the doses are high enough to suspect Acro, but if you haven't looked before at the symptom list, might be worth reading through and seeing if it rings a bell?
If you have good results on cycle 1 of a dose, with a U-curve and a dip to a better-than-normal nadir, but then lose those results on cycle 2, my understanding & experience with PZI is that it means their body has overcome that dose. The cycle 1 result is the "wow factor", and then after they get over the "wow", they go "nah, not enough insulin". Someone (Rob?) described it once as like a drug addict - keep needing more to get the same insulin high. Of course other explanations are possible I suppose, and you don't know for certain what happened last night - for instance if he got a good nadir, today could be a pink reaction cycle. Given his history though (no known low nadirs, and signs of possible insulin resistance (?)), I would suspect there was no good nadir last night.
I would probably give it another cycle tonight on this dose, and if you can, get a nadir test. If no improvement, I'd consider raising again. I'd like to hear what others think though. Especially as you get into higher doses with not a lot of response, I start to feel out of my league. Have you ever tested him for insulin resistence? I don't think the doses are high enough to suspect Acro, but if you haven't looked before at the symptom list, might be worth reading through and seeing if it rings a bell?
Rob & Harley (GA)
Very Active Member
Re: 1/8 Mickey amps 342 +7 304
I guess I would give it a couple of cycles to make sure it isn't a bounce and then up the dose again.
I guess I would give it a couple of cycles to make sure it isn't a bounce and then up the dose again.
Charliemeow
Very Active Member
Good description, Joanna. Gator mentioned that thought with me to explain some wonkiness in Charlie's numbers, but your way of wording it makes it make more sense to me. No offense to Gator if you're reading this! ;-)
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