? 1/28 thru 1/30 TiTI still climbing. How serious is this? Another dosecrease to 14U?

[Kathy and TiTi]

http://www.felinediabetes.com/FDMB/...-yellow-and-yellow-still.172084/#post-1881943

Need some help and clarification in how to proceed. She's peeing too much, indicating stress on her kidneys, as they take attempt to manage huge volumes of fluids. I am feeling somewhat hopeless. It's difficult to believe that she will pull out of this. This climb began December 21st. It's now January 30th, and there's no end in sight.
Here is my question
If the pulsation of the presumed tumor is cancelling out the insulin, what is happening?:

• Obviously some insulin is reaching her system, or she would be in continuous black figures. Right?
• This continuous dose-creasing seems iffy to me, since clearly she is responding to it at times, and then not responding at other times.
• Since I cannot stay up all night to monitor her BG, it is possible that she is sometimes going low and even too low.
• The very same dose of insulin may be too high for her at certain times, and then too low for her at certain other times. This discrepancy in reaction would be due to the pulsation. Correct?
• If so, it seems probably that she could crash suddenly if the pulsation slows or ends.

 

[Gill & George]

Hi Kathy I can't help with all your questions.

1) I think there is some bouncing going on that 401 on 1/28 makes me think she might have hit green in the previous cycle.
2) she may have gone lower than the 147 on 1/29, probably not too low, but enough to trigger another bounce.
3) she does look like she's gone lower at night.
4) I think I would probably wait and see where she lands when she clears this bounce, I might look for her clearing it tonight or tomorrow am.

Hopefully @Wendy&Neko or @julie & punkin (ga) may be able to help you with the high dose questions, they may also have a different view on the dosecrease.

 

[Kathy and TiTi]

Actually that is exactly what I am thinking. If I slept during the day, and was up at night, I might be able to better manage this unfortunate pattern.
My fear is that she's on both too high a dose, and too low a dose, depending on what her system is able to do with the insulin at various times during each 12 hour cycle.

 

[Wendy&Neko]

Since you saw blue on this dose, I might be inclined to hold it for at least 8 cycles. That goes with Gill's point #4 above.

I wouldn't worry too much about staying up all night every night with Titi. Looking back at her spreadsheet, you can usually tell by +4 if she's going low in any particular cycle. If you see her +3 or +4 is lower than PMPS and green or close to it, it may warrant a later test. Titi is probably just doing a lot of bouncing. I found with Neko that if she didn't keep seeing green every few days, she got a lot bouncier and I'd have to increase and keep her seeing green to slow the bouncing.

The pulsing of the acro tumour doesn't usually happen that quickly. It's not like a faucet you turn on and off. The tumour grows for a while, thens slows down or stops changing for a while and her dose needs become static. Some of the tumour cells may die off and her dose needs may go down again for a while, then new cells may start growing again.

 

[carfurby (GA)]