Hi Angela,
Regarding R, what time zone are you in and what times do you shoot?
It's important you give the new L dose a chance to show what it may or may not do without the influence of R.
I recommend waiting at least until 3 cycles of your new dose (22u) are complete before considering starting your R trial.
You want to try and avoid R trials on a cycle when a new dose kicking in and showing action. The combined effects could result in a quick steep drop, which could trigger a wicked bounce. Giving R as a bounce is breaking is also to be avoided for the same reason.
You can do your first trial either AM or PM cycle. Whichever you choose you must be able to monitor +1,+2,+3 and +4 and possibly a +5.
I can be available on Thursday 6/1 if you want to give it a try.
In the mean time, can you tell me what the recent appetite issues are about? They seem to be curiously limited to the mornings.